ChemicalBook > CAS DataBase List > 4-Amino-1-benzylpiperidine

4-Amino-1-benzylpiperidine

Product Name
4-Amino-1-benzylpiperidine
CAS No.
50541-93-0
Chemical Name
4-Amino-1-benzylpiperidine
Synonyms
1-BENZYLPIPERIDIN-4-AMINE;1-BENZYL-PIPERIDIN-4-YLAMINE;4-(PIPERIDIN-1-YLMETHYL)ANILINE;4-Piperi;AKOS B014375;AKOS MSC-0180;ASISCHEM W54645;1-benzyl-4-aMino;AKOS BOR-MOSH-08;AKOS BBS-00006436
CBNumber
CB1100925
Molecular Formula
C12H18N2
Formula Weight
190.28
MOL File
50541-93-0.mol
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4-Amino-1-benzylpiperidine Property

Melting point:
121-122 °C(Solv: water (7732-18-5); ethanol (64-17-5))
Boiling point:
152 °C (9.7 mmHg)
Density 
0.933 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.543(lit.)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
10g/l
form 
Liquid
pka
10.15±0.20(Predicted)
color 
Clear colorless to light yellow
PH
11.4 (10g/l, H2O)
Water Solubility 
immiscible
Sensitive 
Air Sensitive
BRN 
146038
InChIKey
YUBDLZGUSSWQSS-UHFFFAOYSA-N
CAS DataBase Reference
50541-93-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-36
Safety Statements 
26-36
WGK Germany 
3
8-10-34
HazardClass 
IRRITANT
HS Code 
29333999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
195812
Product name
4-Amino-1-benzylpiperidine
Purity
98%
Packaging
5g
Price
$46.4
Updated
2024/03/01
Sigma-Aldrich
Product number
195812
Product name
4-Amino-1-benzylpiperidine
Purity
98%
Packaging
25g
Price
$116
Updated
2024/03/01
TCI Chemical
Product number
A1086
Product name
4-Amino-1-benzylpiperidine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$93
Updated
2024/03/01
TCI Chemical
Product number
A1086
Product name
4-Amino-1-benzylpiperidine
Purity
>98.0%(GC)(T)
Packaging
100g
Price
$267
Updated
2024/03/01
Alfa Aesar
Product number
A10149
Product name
4-Amino-1-benzylpiperidine, 98%
Packaging
25g
Price
$101
Updated
2021/12/16
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4-Amino-1-benzylpiperidine Chemical Properties,Usage,Production

Chemical Properties

clear colourless to light yellow liquid

Uses

4-Amino-1-benzylpiperidine was used in the preparation of:

  • butyl 4-amino-1-piperidineacetate, key intermediate required for the synthesis of butyl 4-[(4-amino-5-chloro-2-methoxybenzoyl)amino]-1-piperidineacetate
  • 5-alkylimino-1,2,4-thiadiazolidine-3-ones, such as 4-ethyl-5-[imino-[1-(phenylmethyl)-4-piperidinyl]]-2-methyl-1,2,4-thiadiazolidin-3-one and 4-benzyl-5-[imino-[1-(phenylmethyl)-4-piperidinyl]]-2-isopropyl-1,2,4-thiadiazolidin-3-one
  • glycyrrhetinic acid derivatives

Purification Methods

Purify it by distillation in vacuo and store it under N2 because it absorbs CO2. The dihydrochloride salt [1205-72-7] has m 270-273o (255o) after recrystallisation from MeOH/EtOAc or EtOH. [Brookes J Chem Soc 3165, 3172 1957.] The 4-methylamino-1-benzylpiperidine derivative has b 168-172o/17mm, nD 1.5367 [Reitsema & Hunter J Am Chem Soc 70 4009 1948]. The 1-(1-benzyl-4-piperidinyl)-3-cyano-2-methylisothiourea derivative has m 160o from CHCl3/Et2O [Preparation, IR, NMR: Ried et al. Chem Ber 116 1547 1983, Beilstein 22 III/IV 3752].

4-Amino-1-benzylpiperidine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Amino-1-benzylpiperidine Suppliers

Nantong Xiaochang Pharmaceutical Trading Co., Ltd.
Tel
0513-82104991 18912868322
Fax
QQ1907456386
Email
sales11@btcpharm.com
Country
China
ProdList
1332
Advantage
58
Anhui Dexinjia Biopharm Co., Ltd
Tel
0531-82375878 15269101859
Email
2710825968@qq.com
Country
China
ProdList
297
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
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View Lastest Price from 4-Amino-1-benzylpiperidine manufacturers

Anhui Ruihan Technology Co., Ltd
Product
4-Amino-1-benzylpiperidine 50541-93-0
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2023-09-08
Henan Bao Enluo International TradeCo.,LTD
Product
4-Amino-1-benzylpiperidine 50541-93-0
Price
US $150.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
10000MT
Release date
2023-05-29
Hebei Mingeng Biotechnology Co., Ltd
Product
4-Amino-1-benzylpiperidine 50541-93-0
Price
US $120.00/KG
Min. Order
10g
Purity
99%
Supply Ability
500kg/month
Release date
2021-12-21

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