Eledoisin
Description Background- Product Name
- Eledoisin
- CAS No.
- 69-25-0
- Chemical Name
- Eledoisin
- Synonyms
- ELEDOSIN;ELEDOISIN;eledonepeptide;Eledosin Acetate;Eledoisin Acetate;PYR-PSKDAFIGLM-NH2;Eledoisin USP/EP/BP;Eledoisin,Eledone peptide;Eledoisin,Eledone peptide, >99%;GLP-PRO-SER-LYS-ASP-ALA-PHE-ILE-GLY-LEU-MET-NH2
- CBNumber
- CB8186874
- Molecular Formula
- C54H85N13O15S
- Formula Weight
- 1188.4
- MOL File
- 69-25-0.mol
Eledoisin Property
- Melting point:
- 230 °C (decomp)
- Boiling point:
- 1618.1±65.0 °C(Predicted)
- Density
- 1.289±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- DMF: 15 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:20): 0.04 mg/ml
- form
- A crystalline solid
- pka
- 4.19±0.10(Predicted)
- color
- White to off-white
- optical activity
- -4422 (95% Acetic Acid)
- Sequence
- {Glp}-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2
- InChIKey
- AYLPVIWBPZMVSH-UHFFFAOYSA-N
- SMILES
- C(C1NC(=O)CC1)(N1CCCC1C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CC(O)=O)C(=O)NC(C)C(=O)NC(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(C(=O)N)CCSC)CC1C=CC=CC=1)=O
Safety
- WGK Germany
- 3
- RTECS
- JX8688000
- HS Code
- 3504009000
N-Bromosuccinimide Price
- Product number
- 28810
- Product name
- Eledoisin
- Packaging
- 1mg
- Price
- $86
- Updated
- 2024/03/01
- Product number
- 28810
- Product name
- Eledoisin
- Packaging
- 10mg
- Price
- $588
- Updated
- 2024/03/01
- Product number
- 28810
- Product name
- Eledoisin
- Packaging
- 5mg
- Price
- $336
- Updated
- 2024/03/01
- Product number
- 255233
- Product name
- Eledoisin
- Packaging
- 1mg
- Price
- $310
- Updated
- 2021/12/16
- Product number
- PEP0001267
- Product name
- ELEDOISIN
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $450
- Updated
- 2021/12/16
Eledoisin Chemical Properties,Usage,Production
Uses
Eledoisin (Eledone peptide) is a specific agonist of NK2 and NK3 receptors.
Definition
ChEBI: Eledoisin is a peptide.
in vivo
Eledoisin (Eledone peptide; 0.1-1 nmol/kg) injected into rats produces a biphasic cardiovascular response that consists of an initial fall of systemic blood pressure (8-15 mm Hg) followed by a rise (20-22 mm Hg). Intracerebroventricular injection of Eledoisin produces an enhancement of grooming and scratching behavior in mice[2].
IC 50
NK2; NK3
Description
Eledoisin’s molecular weight is 1188.4 having an amino acid sequence of Glp-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2 and a molecular formula of C54H85N13O15S.
Background
Eledoisin is an undecapeptide formed in the venom gland of several species of octopuses and is used as a vasodilator and a contraction agent of extravascular smooth muscle.
References
[1] Lippe C, et al. Eledoisin and Kassinin, but not Enterokassinin, stimulate ion transport in frog skin. Peptides. 2004 Nov;25(11):1971-5. DOI:10.1016/j.peptides.2004.06.014
[2] Severini C, et al. The tachykinin peptide family. Pharmacol Rev. 2002 Jun;54(2):285-322. DOI:10.1124/pr.54.2.285
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View Lastest Price from Eledoisin manufacturers
- Product
- Eledoisin 69-25-0
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- 98%min
- Supply Ability
- 1000g
- Release date
- 2023-01-12
- Product
- Eledoisin 69-25-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-11
- Product
- Eledoisin 69-25-0
- Price
- US $40.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 10 tons
- Release date
- 2023-09-18