Description Background
ChemicalBook > CAS DataBase List > Eledoisin

Eledoisin

Description Background
Product Name
Eledoisin
CAS No.
69-25-0
Chemical Name
Eledoisin
Synonyms
ELEDOSIN;ELEDOISIN;eledonepeptide;Eledosin Acetate;Eledoisin Acetate;PYR-PSKDAFIGLM-NH2;Eledoisin USP/EP/BP;Eledoisin,Eledone peptide;Eledoisin,Eledone peptide, >99%;GLP-PRO-SER-LYS-ASP-ALA-PHE-ILE-GLY-LEU-MET-NH2
CBNumber
CB8186874
Molecular Formula
C54H85N13O15S
Formula Weight
1188.4
MOL File
69-25-0.mol
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Eledoisin Property

Melting point:
230 °C (decomp)
Boiling point:
1618.1±65.0 °C(Predicted)
Density 
1.289±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
DMF: 15 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:20): 0.04 mg/ml
form 
A crystalline solid
pka
4.19±0.10(Predicted)
color 
White to off-white
optical activity
-4422 (95% Acetic Acid)
Sequence
{Glp}-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2
InChIKey
AYLPVIWBPZMVSH-UHFFFAOYSA-N
SMILES
C(C1NC(=O)CC1)(N1CCCC1C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CC(O)=O)C(=O)NC(C)C(=O)NC(C(=O)NC(C(C)CC)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(C(=O)N)CCSC)CC1C=CC=CC=1)=O
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Safety

WGK Germany 
3
RTECS 
JX8688000
HS Code 
3504009000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28810
Product name
Eledoisin
Packaging
1mg
Price
$86
Updated
2024/03/01
Cayman Chemical
Product number
28810
Product name
Eledoisin
Packaging
10mg
Price
$588
Updated
2024/03/01
Cayman Chemical
Product number
28810
Product name
Eledoisin
Packaging
5mg
Price
$336
Updated
2024/03/01
Usbiological
Product number
255233
Product name
Eledoisin
Packaging
1mg
Price
$310
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0001267
Product name
ELEDOISIN
Purity
95.00%
Packaging
1MG
Price
$450
Updated
2021/12/16
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Eledoisin Chemical Properties,Usage,Production

Uses

Eledoisin (Eledone peptide) is a specific agonist of NK2 and NK3 receptors.

Definition

ChEBI: Eledoisin is a peptide.

in vivo

Eledoisin (Eledone peptide; 0.1-1 nmol/kg) injected into rats produces a biphasic cardiovascular response that consists of an initial fall of systemic blood pressure (8-15 mm Hg) followed by a rise (20-22 mm Hg). Intracerebroventricular injection of Eledoisin produces an enhancement of grooming and scratching behavior in mice[2].

IC 50

NK2; NK3

Description

Eledoisin’s molecular weight is 1188.4 having an amino acid sequence of Glp-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2 and a molecular formula of C54H85N13O15S.

Background

Eledoisin is an undecapeptide formed in the venom gland of several species of octopuses and is used as a vasodilator and a contraction agent of extravascular smooth muscle.

References

[1] Lippe C, et al. Eledoisin and Kassinin, but not Enterokassinin, stimulate ion transport in frog skin. Peptides. 2004 Nov;25(11):1971-5. DOI:10.1016/j.peptides.2004.06.014
[2] Severini C, et al. The tachykinin peptide family. Pharmacol Rev. 2002 Jun;54(2):285-322. DOI:10.1124/pr.54.2.285

Eledoisin Preparation Products And Raw materials

Raw materials

Preparation Products

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Eledoisin Suppliers

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View Lastest Price from Eledoisin manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Eledoisin 69-25-0
Price
US $0.00/g
Min. Order
1g
Purity
98%min
Supply Ability
1000g
Release date
2023-01-12
Henan Aochuang Chemical Co.,Ltd.
Product
Eledoisin 69-25-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-11
Hebei Yanxi Chemical Co., Ltd.
Product
Eledoisin 69-25-0
Price
US $40.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-09-18

69-25-0, EledoisinRelated Search:


  • eledonepeptide
  • ELEDOISIN
  • GLP-PRO-SER-LYS-ASP-ALA-PHE-ILE-GLY-LEU-MET-NH2
  • 5-oxo-l-prolyl-l-prolyl-l-seryl-l-lysyl-l-aspartyl-l-alanyl-l-phenylalanyl-l-isoleucylglycyl-l-leucyl-l-methioninamide
  • PYR-PRO-SER-LYS-ASP-ALA-PHE-ILE-GLY-LEU-MET-NH2
  • PYR-PSKDAFIGLM-NH2
  • PGLU-PRO-SER-LYS-ASP-ALA-PHE-ILE-GLY-LEU-MET-NH2
  • ELEDOSIN
  • 5-Oxo-L-Pro-L-Pro-L-Ser-L-Lys-L-Asp-L-Ala-L-Phe-L-Ile-Gly-L-Leu-L-Met-NH2
  • Eledoisin Acetate
  • Eledosin Acetate
  • 5-methyl-2-[[4-(4-methylanilino)-9,10-dioxo-1-anthracenyl]amino]benzenesulfonic acid
  • Eledoisin,Eledone peptide, >99%
  • Eledoisin USP/EP/BP
  • Eledoisin,Eledone peptide
  • 69-25-0
  • C54H85N13O15S1
  • C54H86N13O15S
  • C54H85N13O15S
  • proteins
  • Peptide