DIGITOXIGENIN
- Product Name
- DIGITOXIGENIN
- CAS No.
- 143-62-4
- Chemical Name
- DIGITOXIGENIN
- Synonyms
- echujetin;evonogenin;NSC 407806;cerberigenin;THEVETIGENIN;igitoxigenin;DIGITOXYGENIN;DIGITOXIGENIN;digitoxigenine;Digitoxigenin >
- CBNumber
- CB8187462
- Molecular Formula
- C23H34O4
- Formula Weight
- 374.51
- MOL File
- 143-62-4.mol
DIGITOXIGENIN Property
- Melting point:
- 253-255 °C (dec.)(lit.)
- alpha
- D17 +19.1° (c = 1.36 in methanol)
- Boiling point:
- 423.5°C (rough estimate)
- Density
- 1.0284 (rough estimate)
- refractive index
- 1.4433 (estimate)
- storage temp.
- Store at -20°C
- solubility
- DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 20 mg/ml; Ethanol: 5 mg/ml
- pka
- 14.93±0.70(Predicted)
- form
- powder to crystal
- color
- White to Almost white
- Water Solubility
- 11.24mg/L(30 ºC)
- Merck
- 14,3162
- BRN
- 95448
- Stability:
- Hygroscopic
- LogP
- 2.640
- CAS DataBase Reference
- 143-62-4(CAS DataBase Reference)
Safety
- Hazard Codes
- T
- Risk Statements
- 25
- Safety Statements
- 45
- RIDADR
- UN 3462 6.1/PG 2
- WGK Germany
- 3
- RTECS
- FH4975000
- HS Code
- 2938.90.0000
- HazardClass
- 6.1(a)
- PackingGroup
- II
- Toxicity
- cat,LDLo,intravenous,254ug/kg (0.254mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITING,Journal of the American Pharmaceutical Association. Vol. 27, Pg. 189, 1938.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H300Fatal if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D9404
- Product name
- Digitoxigenin
- Purity
- non-ionic
- Packaging
- 10mg
- Price
- $101
- Updated
- 2024/03/01
- Product number
- D9404
- Product name
- Digitoxigenin
- Purity
- non-ionic
- Packaging
- 100mg
- Price
- $618
- Updated
- 2024/03/01
- Product number
- D0541
- Product name
- Digitoxigenin
- Purity
- >97.0%(HPLC)
- Packaging
- 10mg
- Price
- $219
- Updated
- 2024/03/01
- Product number
- 18229
- Product name
- Digitoxigenin
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $44
- Updated
- 2024/03/01
- Product number
- 18229
- Product name
- Digitoxigenin
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $78
- Updated
- 2024/03/01
DIGITOXIGENIN Chemical Properties,Usage,Production
Uses
Cardiotonic;Na+ K+ ATPase inhibitor
Definition
ChEBI: Digitoxigenin is a 5beta-cardenolide that is 5beta-cardanolide with hydroxy substituents at the 3beta- and 14beta-positions and double bond unsaturation at C(20)-C(22). It is a 3beta-hydroxy steroid and a 14beta-hydroxy steroid. It derives from a hydride of a 5beta-cardanolide.
Purification Methods
Dissolve digitoxigenin in EtOAc, wash it with H2O, dry it (Na2SO4), evaporate and recrystallise it from 40% aqueous EtOH or aqueous MeOH then EtOAc/Et2O. The UV has max at 218nm ( 14,500 M-1cm-1). The 3-acetate crystallises from Me2CO/Et2O with m 222-227o, [] D 20 +21o (c 1, CHCl3). [Wyss et al. Helv Chim Acta 43 644 1960, Cruz et al. J Org Chem 4 2 3580 1977, Beilstein 18 IV 1468.]
DIGITOXIGENIN Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from DIGITOXIGENIN manufacturers
- Product
- DIGITOXIGENIN 143-62-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000ton
- Release date
- 2023-08-23