6-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

Product Name: 6-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
CAS No.: 122794-99-4
Chemical Name: 6-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
Synonyms: DK498;BUTTPARK 21\09-49;6-bromo-4-hydroxyquinoL;ETHYL 6-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLATE;ETHYL 6-BROMO-4-HYDROXY-3-QUINOLINECARBOXYLATE;Ethyl 4-hydroxy-6-broMoquinoline-3-carboxylate;ethyl 6-bromo-1,4-dihydro-4-oxoquinoline-3-carboxylate;4-Hydroxy-6-broMoquinoline-3-carboxylic acid ethyl ester;6-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER;Ethyl 6-bromo-4-hydroxy-3,5-dihydroquinoline-3-carboxylate
CBNumber: CB8194000
Molecular Formula: C12H10BrNO3
Formula Weight: 296.12
MOL File: 122794-99-4.mol

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6-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Property

Melting point:: 326-329°C
Boiling point:: 385.5±37.0 °C(Predicted)
Density: 1.593
storage temp.: Inert atmosphere,Room Temperature
pka: 2.16±0.50(Predicted)
form: solid
Appearance: White to light brown Solid
InChI: InChI=1S/C12H10BrNO3/c1-2-17-12(16)9-6-14-10-4-3-7(13)5-8(10)11(9)15/h3-6H,2H2,1H3,(H,14,15)
InChIKey: IVZIOBTVAJBBAS-UHFFFAOYSA-N
SMILES: N1C2C(=CC(Br)=CC=2)C(O)=C(C(OCC)=O)C=1

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Safety

Hazard Codes: Xi
Risk Statements: 36
Safety Statements: 26
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933499090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H319Causes serious eye irritation
Precautionary statements: P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: BBO000201
Product name: 6-Bromo-4-hydroxyquinoline-3-carboxylic acid ethyl ester
Purity: Aldrich
Packaging: 1g
Price: $107
Updated: 2025/07/31

TRC

Product number: E900730
Product name: Ethyl6-bromo-4-hydroxyquinoline-3-carboxylate
Packaging: 250mg
Price: $55
Updated: 2021/12/16

TRC

Product number: E900730
Product name: Ethyl6-bromo-4-hydroxyquinoline-3-carboxylate
Packaging: 1g
Price: $75
Updated: 2021/12/16

ChemScene

Product number: CS-M0117
Product name: ethyl6-bromo-4-hydroxyquinoline-3-carboxylate
Packaging: 10g
Price: $76
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-9-Y9
Product name: Ethyl 6-bromo-4-hydroxyquinoline-3-carboxylate
Purity: 98%
Packaging: 25g
Price: $240
Updated: 2021/12/16

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6-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Chemical Properties,Usage,Production

Synthesis

101937-44-4

79607-23-1

The general procedure for the synthesis of ethyl 6-bromo-4-oxo-1,4-dihydroquinoline-3-carboxylate from diethyl 2-(((4-bromophenyl)amino)methylene)malonate was as follows: intermediate 3c (330 mg, 0.879 mmol) was transferred to a microwave reaction tube and dissolved in 2 mL diphenyl ether. The reaction was carried out at 250 °C with microwave radiation for 5 min. After completion of the reaction, petroleum ether was added and the precipitate precipitated was collected by filtration. The resulting product was confirmed as ethyl 6-bromo-4-oxo-1,4-dihydroquinoline-3-carboxylate in quantitative yield by 1H-NMR analysis.

References

[1] Patent: WO2009/40377, 2009, A2. Location in patent: Page/Page column 19
[2] Patent: WO2016/10869, 2016, A2. Location in patent: Page/Page column 16
[3] Patent: WO2017/11363, 2017, A1. Location in patent: Page/Page column 16
[4] ACS Medicinal Chemistry Letters, 2017, vol. 8, # 3, p. 350 - 354
[5] European Journal of Medicinal Chemistry, 2014, vol. 79, p. 413 - 421

6-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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6-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER Suppliers

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View Lastest Price from 6-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER manufacturers

Career Henan Chemical Co

Product: 6-Bromo-4-Hydroxyquinoline-3-Carboxylic Acid Ethyl Ester 122794-99-4
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-09

Career Henan Chemical Co

Product: 6-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 122794-99-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95-99%
Supply Ability: 1ton
Release date: 2020-01-08

122794-99-4, 6-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTERRelated Search:

4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID 4-Hydroxyquinoline 8-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 6-BROMO-4-HYDROXYQUINOLINE 6-Bromoquinoline 6-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID Methyl 4-hydroxynicotinate 3-(3-BROMO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER 4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER 6-BROMOQUINOLINE-3-CARBOXYLIC ACID ETHYL 6-BROMO-8-CHLORO-4-HYDROXY-QUINOLINE-3-CARBOXYLATE 3-(3-BROMO-PHENYL)-3-OXO-PROPIONIC ACID METHYL ESTER 4-HYDROXY-NICOTINIC ACID ETHYL ESTER 6-BROMO-3-METHYLQUINOLINE 6-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER CHEMBRDG-BB 5870418 3-(3-BROMO-PHENYL)-PROPIONIC ACID ETHYL ESTER 7-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER, 95+%

ETHYL 6-BROMO-4-HYDROXY-3-QUINOLINECARBOXYLATE

ETHYL 6-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLATE

BUTTPARK 21\09-49

6-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER

4-Hydroxy-6-broMoquinoline-3-carboxylic acid ethyl ester

Ethyl 4-hydroxy-6-broMoquinoline-3-carboxylate

6-Bromo-3-(ethoxycarbonyl)-4-hydroxyquinoline, 6-Bromo-3-(ethoxycarbonyl)-4-hydroxy-1-azanaphthalene

3-QUINOLINECARBOXYLICACID, 6-BROMO-4-HYDROXY-, ETHYL ESTER (RELATED REFERENCE)

6-bromo-4-hydroxyquinoL

3-Quinolinecarboxylic acid, 6-bromo-4-hydroxy-, ethyl ester

6-BROMO-4-HYDROXYQUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER ISO 9001：2015 REACH

ethyl 6-bromo-1,4-dihydro-4-oxoquinoline-3-carboxylate

DK498

Ethyl 6-bromo-4-hydroxy-3,5-dihydroquinoline-3-carboxylate

122794-99-4