ChemicalBook > CAS DataBase List > (3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One

(3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One

Product Name
(3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One
CAS No.
163222-32-0
Chemical Name
(3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One
Synonyms
ZTB-8;1-(4-F;EZ-ETL;Ezetimibe Benzyl;Benzylated Ezetimibe;4'-O-Benzyl EzetiMibe;4’-O-Benzyl Ezetimibe;4’-O-Benzyloxy Ezetimibe;Ezetimibe Intermediate-L;EzetiMibe Benzyl IMpurity
CBNumber
CB8197788
Molecular Formula
C31H27F2NO3
Formula Weight
499.55
MOL File
163222-32-0.mol
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(3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One Property

Melting point:
176 - 178°C
Boiling point:
706.5±60.0 °C(Predicted)
Density 
1.270
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
14.15±0.20(Predicted)
color 
Off-White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B286310
Product name
4’-O-BenzyloxyEzetimibe
Packaging
5mg
Price
$145
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB18410
Product name
4'-O-Benzyloxy ezetimibe
Packaging
250mg
Price
$150
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB18410
Product name
4'-O-Benzyloxy ezetimibe
Packaging
500mg
Price
$250
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB18410
Product name
4'-O-Benzyloxy ezetimibe
Packaging
100mg
Price
$100
Updated
2021/12/16
AK Scientific
Product number
9213AJ
Product name
(3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-[4-(phenylmethoxy)phenyl]-2-azetidinone
Packaging
250mg
Price
$126
Updated
2021/12/16
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(3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

(3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4-Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One is protected Ezetimibe, used for the synthesis of related derivatives.

(3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One Preparation Products And Raw materials

Raw materials

Preparation Products

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(3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One Suppliers

Canada 1 China 113 Germany 1 India 11 Ukraine 1 United Kingdom 4 United States 8 Global 139
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View Lastest Price from (3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One manufacturers

Career Henan Chemical Co
Product
(3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One 163222-32-0
Price
US $1.80-3.60/KG
Min. Order
1KG
Purity
99%
Supply Ability
88KG
Release date
2019-09-04
Career Henan Chemical Co
Product
me: 2-AZETIDINONE, 1-(4-FLUOROPHENYL)-3-[(3S)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL]-4-[4-(PHENYLMETHOXY)PHENYL]-, (3R,4S)- 163222-32-0
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20kg
Release date
2018-08-07

163222-32-0, (3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-OneRelated Search:

3-O-Acetyl Ezetimibe ent-EzetiMibe 3-[5-(1,5-Dioxo-5-(p-fluophenylpentyl]-4R-phenyl-2-oxazolidinone (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid Methyl (3R,4S)-1-(4-fluorophenyl)-2-oxo-4-[4-(phenylmethoxy)phenyl]-3-azetidinepropanoate (3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one Ezetimibe EZETIMIBE-D4 1,5-Pentanedione, 1,5-bis(4-fluorophenyl)- 5-(4-FLUOROPHENYL)VALERIC ACID EzetiMibe (3R,4R,3'S)-IsoMer (R)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one (3R,4R)-1-(4-fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one (4S)-3-(2,2-dimethylpropanoyl)-4-phenyl-1,3-oxazolidin-2-one 4-BENZOYLBUTYRIC ACID 5-(2-FLUOROPHENYL)-5-OXOVALERIC ACID Ezetimibe Impurity 72 N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline

  • 2-AZETIDINONE, 1-(4-FLUOROPHENYL)-3-[(3S)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL]-4-[4-(PHENYLMETHOXY)PHENYL]-, (3R,4S)-
  • 1-(4-FLUOROPHENYL)-3-[(3S)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL]-4-[4-(PHENYLMETHOXY)PHENYL]-, (3R,4S)-2-AZETIDINONE
  • 1-(4-Fluorophenyl)-3-[(3s)-3-(4-Fluorophenyl)-3-Hydroxypropyl]-4-[4-(Phenylmethoxy)Phenyl-(3r,4s)-2-Azetidinone
  • 1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-[4-phenylmethoxy]phenyl]-(3R,4S)-2-azetidinone (intermediate of ezetimibe)
  • (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-[4-(phenylmethoxy)phenyl]-2-azetidinone
  • E7:synthesis of trans-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl-(4-benzyloxyphenyl)]-2-azetidinone
  • 4’-O-Benzyloxy Ezetimibe
  • (3R,4S)-4-[(4-Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-2-azetidinone
  • 1-(4-F
  • (3R)-3-[1-(benzyloxy)cyclohexa-2,4-dien-1-yl]-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]azetidin-2-one
  • (3R,4S)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)azetidin-2-one
  • EzetiMibe Benzyl IMpurity
  • Ezetimibe?Benzyl Ether Impurity
  • 1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-phenylmethoxyphenyl)-2-azetidinone
  • Azetidinone, 1-(4-Fluorophenyl)-3-[(3S)-3-(4-Fluorophenyl)-3-Hydroxypropyl]-4-[4-(PhenylMethoxy)phenyl]-, (3R,4S)-
  • 4'-O-Benzyl EzetiMibe
  • EZ-ETL
  • me: 2-AZETIDINONE, 1-(4-FLUOROPHENYL)-3-[(3S)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL]-4-[4-(PHENYLMETHOXY)PHENYL]-, (3R,4S)-
  • 1-Phenyl-3R-[3-(4-Fluorophenyl-3S-Hydroxypropyl]-4S-(4-Hydroxyphenyl-AzetidiN-2-One
  • ZTB-8
  • (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-Fluorophenyl)-3-Hydroxypropyl]-4-[4-(Phenylmethoxy)phenyl]-Azetidinone
  • Ezetimibe Impurity 14(Intermediate Impurity)
  • (3R,4S)-1-(4-FLUOROPHENYL)-3-[(3S)-3-(4-FLUORO
  • (3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One ISO 9001：2015 REACH
  • Ezetimibe Benzyl
  • Azetidinone, 1-(4-Fluorophenyl)-3-[(3S)-3-(4-Fluorophenyl)-3...
  • Benzylated Ezetimibe
  • Ezetimibe Intermediate-L
  • (3R,4S)-1-(4-Fluorophenyl)-3-(3S)-3-(4-fluorophenyl)-3-hydroxy-propyl-4-4-(benzyloxy)phenyl-2-azetidinone
  • 2-AZETIDINONE, 1-(4-FLUOROPHENYL)-3-[(3S)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL]-4-[4-(PHENYLMETHOXY)PHENYL]-, (3R,4S)-
  • (3R,4S)-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)- 3(S)-hydroxypropyl]-4-(4-benzyloxyphenyl)-2-azetidinone
  • (3R,4S)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3'-hydroxypropyl)azetidin-2-one
  • 4’-O-Benzyl Ezetimibe
  • 163222-32-0
  • C31H27F2NO3
  • (intermediate of ezetimibe)
  • Ezetimibe intermediates
  • Aromatics
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals