(3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One

Product Name: (3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One
CAS No.: 163222-32-0
Chemical Name: (3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One
Synonyms: ZTB-8;1-(4-F;EZ-ETL;Ezetimibe Benzyl;Benzylated Ezetimibe;4'-O-Benzyl EzetiMibe;4’-O-Benzyl Ezetimibe;4’-O-Benzyloxy Ezetimibe;Ezetimibe Intermediate-L;4'-O-Benzyloxy Ezetimibe
CBNumber: CB8197788
Molecular Formula: C31H27F2NO3
Formula Weight: 499.55
MOL File: 163222-32-0.mol

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(3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One Property

Melting point:: 176 - 178°C
Boiling point:: 706.5±60.0 °C(Predicted)
Density: 1.270
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly, Heated)
form: Solid
pka: 14.15±0.20(Predicted)
color: Off-White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B286310
Product name: 4’-O-BenzyloxyEzetimibe
Packaging: 5mg
Price: $145
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB18410
Product name: 4'-O-Benzyloxy ezetimibe
Packaging: 250mg
Price: $150
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB18410
Product name: 4'-O-Benzyloxy ezetimibe
Packaging: 500mg
Price: $250
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB18410
Product name: 4'-O-Benzyloxy ezetimibe
Packaging: 100mg
Price: $100
Updated: 2021/12/16

AK Scientific

Product number: 9213AJ
Product name: (3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-[4-(phenylmethoxy)phenyl]-2-azetidinone
Packaging: 250mg
Price: $126
Updated: 2021/12/16

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(3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

(3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4-Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One is protected Ezetimibe, used for the synthesis of related derivatives.

(3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One Preparation Products And Raw materials

Raw materials

Preparation Products

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(3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One Suppliers

Canada 1 China 112 Germany 1 India 10 Ukraine 1 United Kingdom 4 United States 8 Global 137

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Pharmaffiliates Analytics and Synthetics P. Ltd

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A.J Chemicals

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View Lastest Price from (3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One manufacturers

Career Henan Chemical Co

Product: (3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One 163222-32-0
Price: US $1.80-3.60/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 88KG
Release date: 2019-09-04

Career Henan Chemical Co

Product: me: 2-AZETIDINONE, 1-(4-FLUOROPHENYL)-3-[(3S)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL]-4-[4-(PHENYLMETHOXY)PHENYL]-, (3R,4S)- 163222-32-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20kg
Release date: 2018-08-07

163222-32-0, (3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-OneRelated Search:

3-O-Acetyl Ezetimibe ent-EzetiMibe 3-[5-(1,5-Dioxo-5-(p-fluophenylpentyl]-4R-phenyl-2-oxazolidinone (3R,4S)-1-(4-Fluorophenyl)-2-oxo-4-[4-(benzyloxy)phenyl]-3-azetidinepropanoic acid Methyl (3R,4S)-1-(4-fluorophenyl)-2-oxo-4-[4-(phenylmethoxy)phenyl]-3-azetidinepropanoate (3R,4S)-4-[4-(Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]azetidin-2-one Ezetimibe EZETIMIBE-D4 1,5-Pentanedione, 1,5-bis(4-fluorophenyl)- 5-(4-FLUOROPHENYL)VALERIC ACID EzetiMibe (3R,4R,3'S)-IsoMer (R)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one (3R,4R)-1-(4-fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one (4S)-3-(2,2-dimethylpropanoyl)-4-phenyl-1,3-oxazolidin-2-one 4-BENZOYLBUTYRIC ACID 5-(2-FLUOROPHENYL)-5-OXOVALERIC ACID Ezetimibe Impurity 72 N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline

2-AZETIDINONE, 1-(4-FLUOROPHENYL)-3-[(3S)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL]-4-[4-(PHENYLMETHOXY)PHENYL]-, (3R,4S)-

1-(4-FLUOROPHENYL)-3-[(3S)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL]-4-[4-(PHENYLMETHOXY)PHENYL]-, (3R,4S)-2-AZETIDINONE

1-(4-Fluorophenyl)-3-[(3s)-3-(4-Fluorophenyl)-3-Hydroxypropyl]-4-[4-(Phenylmethoxy)Phenyl-(3r,4s)-2-Azetidinone

1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-[4-phenylmethoxy]phenyl]-(3R,4S)-2-azetidinone (intermediate of ezetimibe)

(3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-[4-(phenylmethoxy)phenyl]-2-azetidinone

E7:synthesis of trans-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl-(4-benzyloxyphenyl)]-2-azetidinone

4’-O-Benzyloxy Ezetimibe

(3R,4S)-4-[(4-Benzyloxy)phenyl]-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-2-azetidinone

1-(4-F

(3R)-3-[1-(benzyloxy)cyclohexa-2,4-dien-1-yl]-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]azetidin-2-one

(3R,4S)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)azetidin-2-one

EzetiMibe Benzyl IMpurity

Ezetimibe?Benzyl Ether Impurity

1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-phenylmethoxyphenyl)-2-azetidinone

Azetidinone, 1-(4-Fluorophenyl)-3-[(3S)-3-(4-Fluorophenyl)-3-Hydroxypropyl]-4-[4-(PhenylMethoxy)phenyl]-, (3R,4S)-

4'-O-Benzyl EzetiMibe

EZ-ETL

me: 2-AZETIDINONE, 1-(4-FLUOROPHENYL)-3-[(3S)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL]-4-[4-(PHENYLMETHOXY)PHENYL]-, (3R,4S)-

1-Phenyl-3R-[3-(4-Fluorophenyl-3S-Hydroxypropyl]-4S-(4-Hydroxyphenyl-AzetidiN-2-One

ZTB-8

(3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-Fluorophenyl)-3-Hydroxypropyl]-4-[4-(Phenylmethoxy)phenyl]-Azetidinone

Ezetimibe Impurity 14(Intermediate Impurity)

(3R,4S)-1-(4-FLUOROPHENYL)-3-[(3S)-3-(4-FLUORO

(3R,4S)-4-(4-(Benzyloxy)Phenyl)-1-(4-Fluorophenyl)-3-((S)-3-(4- Fluorophenyl)-3-Hydroxypropyl)Azetidin-2-One ISO 9001：2015 REACH

Ezetimibe Benzyl

Azetidinone, 1-(4-Fluorophenyl)-3-[(3S)-3-(4-Fluorophenyl)-3...

Benzylated Ezetimibe

Ezetimibe Intermediate-L

(3R,4S)-1-(4-Fluorophenyl)-3-(3S)-3-(4-fluorophenyl)-3-hydroxy-propyl-4-4-(benzyloxy)phenyl-2-azetidinone

2-AZETIDINONE, 1-(4-FLUOROPHENYL)-3-[(3S)-3-(4-FLUOROPHENYL)-3-HYDROXYPROPYL]-4-[4-(PHENYLMETHOXY)PHENYL]-, (3R,4S)-

(3R,4S)-1-(4-fluorophenyl)-3-[3-(4-fluorophenyl)- 3(S)-hydroxypropyl]-4-(4-benzyloxyphenyl)-2-azetidinone

(3R,4S)-4-(4-(benzyloxy)phenyl)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3'-hydroxypropyl)azetidin-2-one

4’-O-Benzyl Ezetimibe

4'-O-Benzyloxy Ezetimibe

163222-32-0

C31H27F2NO3

(intermediate of ezetimibe)

Ezetimibe intermediates

Aromatics

Chiral Reagents

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals