ChemicalBook > CAS DataBase List > 5-Amino-2,4,6-triiodoisophthaloyl dichloride

5-Amino-2,4,6-triiodoisophthaloyl dichloride

Product Name: 5-Amino-2,4,6-triiodoisophthaloyl dichloride
CAS No.: 37441-29-5
Chemical Name: 5-Amino-2,4,6-triiodoisophthaloyl dichloride
Synonyms: 5-AMINO-2,4,6-TRIIODOISOPHTHALOYL DICHLORIDE;5-Amino-2,4,6-triiodoisophthalic acid dichloride;ATIPA-DICL;ATIPA DICHLORIDE;Iohexol Impurity 9;5-Amino-2,4,6- trii; Iohexol Impurity L;5-Amino-2,4,6-Triodoisophthalo;Amino triiodisophthaloyl dichloride;5-amino-2,4,6-triiodisophthaloyl dichlor
CBNumber: CB8206516
Molecular Formula: C8H2Cl2I3NO2
Formula Weight: 595.73
MOL File: 37441-29-5.mol

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5-Amino-2,4,6-triiodoisophthaloyl dichloride Property

Melting point:: 231°C(lit.)
Boiling point:: 566.9±50.0 °C(Predicted)
Density: 2.826±0.06 g/cm3(Predicted)
vapor pressure: 0.018Pa at 20℃
storage temp.: Refrigerator, under inert atmosphere
solubility: Acetone (Slightly), Methanol (Very Slightly)
pka: -3.45±0.10(Predicted)
form: Solid
color: Yellow toDark Brown
λmax: 233nm(MeOH)(lit.)
InChI: InChI=1S/C8H2Cl2I3NO2/c9-7(15)1-3(11)2(8(10)16)5(13)6(14)4(1)12/h14H2
InChIKey: FBJVWRITWDYUAC-UHFFFAOYSA-N
SMILES: C1(C(Cl)=O)=C(I)C(N)=C(I)C(C(Cl)=O)=C1I
LogP: 3.7 at 20℃
CAS DataBase Reference: 37441-29-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,N
Risk Statements: 43-51/53
Safety Statements: 22-36/37-61
RIDADR: 3077
HS Code: 2922.49.3700
HazardClass: 9
PackingGroup: III

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: A2854
Product name: 5-Amino-2,4,6-triiodoisophthaloyl Dichloride
Purity: >98.0%(T)
Packaging: 5g
Price: $156
Updated: 2025/07/31

TCI Chemical

Product number: A2854
Product name: 5-Amino-2,4,6-triiodoisophthaloyl Dichloride
Purity: >98.0%(T)
Packaging: 25g
Price: $542
Updated: 2025/07/31

TRC

Product number: A630815
Product name: 5-Amino-2,4,6-triiodoisophthaloyl Dichloride
Packaging: 250mg
Price: $130
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA05533
Product name: 5-Amino-2,4,6,-triiodoisophthaloyl dichloride
Packaging: 5G
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA05533
Product name: 5-Amino-2,4,6,-triiodoisophthaloyl dichloride
Packaging: 10g
Price: $95
Updated: 2021/12/16

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5-Amino-2,4,6-triiodoisophthaloyl dichloride Chemical Properties,Usage,Production

Description

5-Amino-2,4,6-triiodoisophthaloyl dichloride is a triiodinated compound that has been shown to bind to the receptor for asialoglycoprotein. It is used in the diagnosis of liver and kidney diseases. 5-Amino-2,4,6-triiodisophthaloyl acid dichloride is taken up by tissues and organs and causes damage to these tissues. The chloride ion binds to the molecule, making it more water soluble. The lactobionic acid residue is then cleaved off by an enzyme in the cell called beta-galactosidase. This leaves a molecule containing iodine which can be detected with a diagnostic technique such as X-ray crystallography or nuclear magnetic resonance spectroscopy.

Chemical Properties

Yellow Solid

Uses

5-Amino-2,4,6- triiodisophthaloyl acid dichloride is used in the preparation of trimeric X-ray contrast agents.

Preparation

5-Amino-2,4,6-triiodo-isophtalic acid (30 g, 0.054 mol), thionyl chloride (8.2 ml, 0.113 mol) and pyridine (0.2 ml) in 1 ,2 dichloroethane (20 ml) were heated to 70 ℃. A portion of thionyl chloride (15.2 ml, 0.21 mol) was added dropwise during 2 h, and the mixture was heated to 85 ℃ for 6 h. After cooling the reaction mixture to room temperature, it was poured into 300 g of ice-water. The yellow precipitate was filtered off, sucked dry and then washed with water until pH=5. The filter cake was then dried in a vacuum oven for 3 hrs. A light yellow powder was obtained as 5-Amino-2,4,6-triiodisophthaloyl acid dichloride.

Flammability and Explosibility

Not classified

5-Amino-2,4,6-triiodoisophthaloyl dichloride Preparation Products And Raw materials

Raw materials

Dicarboxylic Acid Thionyl chloride

Preparation Products

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View Lastest Price from 5-Amino-2,4,6-triiodoisophthaloyl dichloride manufacturers

Asia Chem I and E (Jiangsu) Co Ltd

Product: 5-Amino-2,4,6-triiodoiso phthaloyl dichloride 37441-29-5
Price: US $90.90/Kg/Drum
Min. Order: 25Kg/Drum
Purity: 98.00%HPLC
Supply Ability: 2tons/month
Release date: 2021-09-23

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 5-Amino-2,4,6-triiodoisophthaloyl dichloride 37441-29-5
Price: US $30.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000kg/week
Release date: 2024-05-28

Hebei Zhanyao Biotechnology Co. Ltd

Product: 5-Amino-2,4,6- Triiodisophthaloyl Acid Dichloride 37441-29-5
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 tons
Release date: 2021-10-11

37441-29-5, 5-Amino-2,4,6-triiodoisophthaloyl dichlorideRelated Search:

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5-amino-2,4,6- triiodisophthaloyl acid dichloride

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5-AMINO-2,4,6-TRIIODOISOPHTHALOYL DICHLORIDE

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5-Amino-2,4,6-Triiodo-1,3-Benzenedicarboxylic Acid Dichloride

5-Amino-2,4,6-triiodoisophthaloydichloride

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5-AMINO-2,4,6-TRIIODOISOPHTALOYL CHLORIDE

5-amino-2,4,6-triodoisophthalolyl chloride 5-Amino-2,4,6-triiodo-1,3-benzenedicar-boxylic acid dichloride

5-amino-2,4,6-triiodo-1,3-benzenedicarbonyldichloride

2,4,6-Triodo-5-Amino Isophthaloyl Chloride (ATIPA DICHLORIDE)

5mino-2,4,6-TriiodoisophthalicAcidDichloride

5-amino-2,4,6-triiodobenzene-1,3-dicarbonyl chloride

Amino triiodisophthaloyl dichloride

5-Amino-2,4,6- trii

ATIPA-DICL

5-Amino-2,4,6-triiodoisophthalic acid dichloride

ATIPA DICHLORIDE

1,3-Benzenedicarbonyldichloride, 5-aMino-2,4,6-triiodo-

5-AMINO 2,4,6, TRIIODOISOTHALYL DICHLORIDE

Iohexol Impurity 9

5-amino-2,4,6-triiodisophthaloyl dichlor

Iohexol Impurity 12（Iohexol EP Impurity L）

5-Amino-2,4,6- triiodisophthaloyl acid dichlorid

5-amino-2,4,6-triiodoisophthalacyl chloride

5-Amino-2,4,6- triiodisophthaloyl acid dichloride ISO 9001：2015 REACH

Iohexol Impurity L

5-Amino-2,4,6-triiodoisophthalic dichloride

5-Amino-2,4,6-triaiodoisophthaloyl chloride

5-Amino-2,4,6-triiodoisophthaIic dichloride

5-amino-2,4, 6-triiodoisophthalyl chloride

5-Amino-2,4,6-triiodisophtha oyl acid dichloride

5-Amino-2,4,6-Triodoisopthaloyl chloride

37441-29-5

10359-25-0

C8H2Cl2I3NO2

Intermediate of Ioversol