ChemicalBook > CAS DataBase List > 5-Amino-2,4,6-triiodoisophthaloyl dichloride

5-Amino-2,4,6-triiodoisophthaloyl dichloride

Product Name
5-Amino-2,4,6-triiodoisophthaloyl dichloride
CAS No.
37441-29-5
Chemical Name
5-Amino-2,4,6-triiodoisophthaloyl dichloride
Synonyms
5-AMINO-2,4,6-TRIIODOISOPHTHALOYL DICHLORIDE;5-Amino-2,4,6-triiodoisophthalic acid dichloride;ATIPA-DICL;ATIPA DICHLORIDE;Iohexol Impurity 9;5-Amino-2,4,6- trii; Iohexol Impurity L;5-Amino-2,4,6-Triodoisophthalo;Amino triiodisophthaloyl dichloride;5-amino-2,4,6-triiodisophthaloyl dichlor
CBNumber
CB8206516
Molecular Formula
C8H2Cl2I3NO2
Formula Weight
595.73
MOL File
37441-29-5.mol
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5-Amino-2,4,6-triiodoisophthaloyl dichloride Property

Melting point:
231°C(lit.)
Boiling point:
566.9±50.0 °C(Predicted)
Density 
2.826±0.06 g/cm3(Predicted)
vapor pressure 
0.018Pa at 20℃
storage temp. 
Refrigerator, under inert atmosphere
solubility 
Acetone (Slightly), Methanol (Very Slightly)
pka
-3.45±0.10(Predicted)
form 
Solid
color 
Yellow toDark Brown
λmax
233nm(MeOH)(lit.)
LogP
3.7 at 20℃
CAS DataBase Reference
37441-29-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,N
Risk Statements 
43-51/53
Safety Statements 
22-36/37-61
RIDADR 
3077
HS Code 
2922.49.3700
HazardClass 
9
PackingGroup 
III
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P272Contaminated work clothing should not be allowed out of the workplace.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2854
Product name
5-Amino-2,4,6-triiodoisophthaloyl Dichloride
Purity
>98.0%(T)
Packaging
5g
Price
$156
Updated
2024/03/01
TCI Chemical
Product number
A2854
Product name
5-Amino-2,4,6-triiodoisophthaloyl Dichloride
Purity
>98.0%(T)
Packaging
25g
Price
$542
Updated
2024/03/01
TRC
Product number
A630815
Product name
5-Amino-2,4,6-triiodoisophthaloyl Dichloride
Packaging
250mg
Price
$130
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA05533
Product name
5-Amino-2,4,6,-triiodoisophthaloyl dichloride
Packaging
100g
Price
$600
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0024319
Product name
5-AMINO-2,4,6-TRIIODISOPHTHALOYL ACID DICHLORIDE
Purity
95.00%
Packaging
2.5G
Price
$1947
Updated
2021/12/16
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5-Amino-2,4,6-triiodoisophthaloyl dichloride Chemical Properties,Usage,Production

Description

5-Amino-2,4,6-triiodoisophthaloyl dichloride is a triiodinated compound that has been shown to bind to the receptor for asialoglycoprotein. It is used in the diagnosis of liver and kidney diseases. 5-Amino-2,4,6-triiodisophthaloyl acid dichloride is taken up by tissues and organs and causes damage to these tissues. The chloride ion binds to the molecule, making it more water soluble. The lactobionic acid residue is then cleaved off by an enzyme in the cell called beta-galactosidase. This leaves a molecule containing iodine which can be detected with a diagnostic technique such as X-ray crystallography or nuclear magnetic resonance spectroscopy.

Chemical Properties

Yellow Solid

Uses

5-Amino-2,4,6- triiodisophthaloyl acid dichloride is used in the preparation of trimeric X-ray contrast agents.

Preparation

5-Amino-2,4,6-triiodo-isophtalic acid (30 g, 0.054 mol), thionyl chloride (8.2 ml, 0.113 mol) and pyridine (0.2 ml) in 1 ,2 dichloroethane (20 ml) were heated to 70 ℃. A portion of thionyl chloride (15.2 ml, 0.21 mol) was added dropwise during 2 h, and the mixture was heated to 85 ℃ for 6 h. After cooling the reaction mixture to room temperature, it was poured into 300 g of ice-water. The yellow precipitate was filtered off, sucked dry and then washed with water until pH=5. The filter cake was then dried in a vacuum oven for 3 hrs. A light yellow powder was obtained as 5-Amino-2,4,6-triiodisophthaloyl acid dichloride.

Flammability and Explosibility

Not classified

5-Amino-2,4,6-triiodoisophthaloyl dichloride Preparation Products And Raw materials

Raw materials

Dicarboxylic Acid Thionyl chloride

Preparation Products

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5-Amino-2,4,6-triiodoisophthaloyl dichloride Suppliers

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View Lastest Price from 5-Amino-2,4,6-triiodoisophthaloyl dichloride manufacturers

Asia Chem I and E (Jiangsu) Co Ltd
Product
5-Amino-2,4,6-triiodoiso phthaloyl dichloride 37441-29-5
Price
US $90.90/Kg/Drum
Min. Order
25Kg/Drum
Purity
98.00%HPLC
Supply Ability
2tons/month
Release date
2021-09-23
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
5-Amino-2,4,6-triiodoisophthaloyl dichloride 37441-29-5
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/week
Release date
2024-05-28
Hebei Zhanyao Biotechnology Co. Ltd
Product
5-Amino-2,4,6- Triiodisophthaloyl Acid Dichloride 37441-29-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2021-10-11

37441-29-5, 5-Amino-2,4,6-triiodoisophthaloyl dichlorideRelated Search:

Oxalyl chloride Benzoyl chloride 3,5,5-Trimethylhexanoyl chloride Glycine Tosyl chloride Chloroacetyl chloride Isobutyryl chloride N-Acetylsulfanilyl chloride Cobalt chloride 4-IODO-M-XYLENE 2-Iodobenzyl chloride 4-Iodobenzoyl chloride 1,3-Bis(chloromethyl)benzene 4-IODO-3-METHYLANILINE 2-Iodo-1,3-dimethylbenzene 3-(Chloromethyl)benzoyl chloride 2,4-Diiodoaniline Isophthaloyl dichloride

  • 5-amino-2,4,6-triodoisophthalolylchloride
  • 5-amino-2,4,6- triiodisophthaloyl acid dichloride
  • 5-AMINO-2,4,6-TRIIODO-ISOPHTALOYL DICHLORIDE
  • 5-AMINO-2,4,6-TRIIODOISOPHTHALOYL DICHLORIDE
  • 5-Amino-2,4,6-Triiodoiso Phthaloyl Chloride
  • 5-Amino-2,4,6-triiodisophthaloyl dichloride
  • 5-Amino-2,4,6-Triiodo-1,3-Benzenedicarboxylic Acid Dichloride
  • 5-Amino-2,4,6-triiodoisophthaloydichloride
  • 5-Amino-2,4,6-Triodoisophthalo
  • 5-AMINO-2,4,6-TRIIODOISOPHTALOYL CHLORIDE
  • 5-amino-2,4,6-triodoisophthalolyl chloride 5-Amino-2,4,6-triiodo-1,3-benzenedicar-boxylic acid dichloride
  • 5-amino-2,4,6-triiodo-1,3-benzenedicarbonyldichloride
  • 2,4,6-Triodo-5-Amino Isophthaloyl Chloride (ATIPA DICHLORIDE)
  • 5mino-2,4,6-TriiodoisophthalicAcidDichloride
  • 5-amino-2,4,6-triiodobenzene-1,3-dicarbonyl chloride
  • Amino triiodisophthaloyl dichloride
  • 5-Amino-2,4,6- trii
  • ATIPA-DICL
  • 5-Amino-2,4,6-triiodoisophthalic acid dichloride
  • ATIPA DICHLORIDE
  • 1,3-Benzenedicarbonyldichloride, 5-aMino-2,4,6-triiodo-
  • 5-AMINO 2,4,6, TRIIODOISOTHALYL DICHLORIDE
  • Iohexol Impurity 9
  • 5-amino-2,4,6-triiodisophthaloyl dichlor
  • Iohexol Impurity 12（Iohexol EP Impurity L）
  • 5-Amino-2,4,6- triiodisophthaloyl acid dichlorid
  • 5-amino-2,4,6-triiodoisophthalacyl chloride
  • 5-Amino-2,4,6- triiodisophthaloyl acid dichloride ISO 9001：2015 REACH
  • Iohexol Impurity L
  • 5-Amino-2,4,6-triiodoisophthalic dichloride
  • 5-Amino-2,4,6-triaiodoisophthaloyl chloride
  • 5-Amino-2,4,6-triiodoisophthaIic dichloride
  • 5-amino-2,4, 6-triiodoisophthalyl chloride
  • 5-Amino-2,4,6-triiodisophtha oyl acid dichloride
  • 5-Amino-2,4,6-Triodoisopthaloyl chloride
  • 37441-29-5
  • C8H2Cl2I3NO2
  • Intermediate of Ioversol