5-Amino-2,4,6-triiodoisophthaloyl dichloride
- Product Name
- 5-Amino-2,4,6-triiodoisophthaloyl dichloride
- CAS No.
- 37441-29-5
- Chemical Name
- 5-Amino-2,4,6-triiodoisophthaloyl dichloride
- Synonyms
- 5-AMINO-2,4,6-TRIIODOISOPHTHALOYL DICHLORIDE;5-Amino-2,4,6-triiodoisophthalic acid dichloride;ATIPA-DICL;ATIPA DICHLORIDE;Iohexol Impurity 9;5-Amino-2,4,6- trii; Iohexol Impurity L;5-Amino-2,4,6-Triodoisophthalo;Amino triiodisophthaloyl dichloride;5-amino-2,4,6-triiodisophthaloyl dichlor
- CBNumber
- CB8206516
- Molecular Formula
- C8H2Cl2I3NO2
- Formula Weight
- 595.73
- MOL File
- 37441-29-5.mol
5-Amino-2,4,6-triiodoisophthaloyl dichloride Property
- Melting point:
- 231°C(lit.)
- Boiling point:
- 566.9±50.0 °C(Predicted)
- Density
- 2.826±0.06 g/cm3(Predicted)
- vapor pressure
- 0.018Pa at 20℃
- storage temp.
- Refrigerator, under inert atmosphere
- solubility
- Acetone (Slightly), Methanol (Very Slightly)
- pka
- -3.45±0.10(Predicted)
- form
- Solid
- color
- Yellow toDark Brown
- λmax
- 233nm(MeOH)(lit.)
- LogP
- 3.7 at 20℃
- CAS DataBase Reference
- 37441-29-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,N
- Risk Statements
- 43-51/53
- Safety Statements
- 22-36/37-61
- RIDADR
- 3077
- HS Code
- 2922.49.3700
- HazardClass
- 9
- PackingGroup
- III
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A2854
- Product name
- 5-Amino-2,4,6-triiodoisophthaloyl Dichloride
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $156
- Updated
- 2024/03/01
- Product number
- A2854
- Product name
- 5-Amino-2,4,6-triiodoisophthaloyl Dichloride
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $542
- Updated
- 2024/03/01
- Product number
- A630815
- Product name
- 5-Amino-2,4,6-triiodoisophthaloyl Dichloride
- Packaging
- 250mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- FA05533
- Product name
- 5-Amino-2,4,6,-triiodoisophthaloyl dichloride
- Packaging
- 100g
- Price
- $600
- Updated
- 2021/12/16
- Product number
- HCH0024319
- Product name
- 5-AMINO-2,4,6-TRIIODISOPHTHALOYL ACID DICHLORIDE
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $1947
- Updated
- 2021/12/16
5-Amino-2,4,6-triiodoisophthaloyl dichloride Chemical Properties,Usage,Production
Description
5-Amino-2,4,6-triiodoisophthaloyl dichloride is a triiodinated compound that has been shown to bind to the receptor for asialoglycoprotein. It is used in the diagnosis of liver and kidney diseases. 5-Amino-2,4,6-triiodisophthaloyl acid dichloride is taken up by tissues and organs and causes damage to these tissues. The chloride ion binds to the molecule, making it more water soluble. The lactobionic acid residue is then cleaved off by an enzyme in the cell called beta-galactosidase. This leaves a molecule containing iodine which can be detected with a diagnostic technique such as X-ray crystallography or nuclear magnetic resonance spectroscopy.
Chemical Properties
Yellow Solid
Uses
5-Amino-2,4,6- triiodisophthaloyl acid dichloride is used in the preparation of trimeric X-ray contrast agents.
Preparation
5-Amino-2,4,6-triiodo-isophtalic acid (30 g, 0.054 mol), thionyl chloride (8.2 ml, 0.113 mol) and pyridine (0.2 ml) in 1 ,2 dichloroethane (20 ml) were heated to 70 ℃. A portion of thionyl chloride (15.2 ml, 0.21 mol) was added dropwise during 2 h, and the mixture was heated to 85 ℃ for 6 h. After cooling the reaction mixture to room temperature, it was poured into 300 g of ice-water. The yellow precipitate was filtered off, sucked dry and then washed with water until pH=5. The filter cake was then dried in a vacuum oven for 3 hrs. A light yellow powder was obtained as 5-Amino-2,4,6-triiodisophthaloyl acid dichloride.
Flammability and Explosibility
Not classified
5-Amino-2,4,6-triiodoisophthaloyl dichloride Preparation Products And Raw materials
Raw materials
Preparation Products
5-Amino-2,4,6-triiodoisophthaloyl dichloride Suppliers
- Tel
- 03-36680489
- Fax
- 03-3668-0520
- Sales-JP@TCIchemicals.com
- Country
- Japan
- ProdList
- 28387
- Advantage
- 80
- Tel
- --
- Fax
- --
- @TCIchemicals.com
- Country
- Japan
- ProdList
- 2741
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@melrob-chemiplus.com
- Country
- Japan
- ProdList
- 208
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@hattoricorp.com
- Country
- Japan
- ProdList
- 1254
- Advantage
- 58
- Tel
- --
- Fax
- --
- em@ksakai.co.jp
- Country
- Japan
- ProdList
- 957
- Advantage
- 58
View Lastest Price from 5-Amino-2,4,6-triiodoisophthaloyl dichloride manufacturers
- Product
- 5-Amino-2,4,6-triiodoisophthaloyl dichloride 37441-29-5
- Price
- US $30.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000kg/week
- Release date
- 2024-05-28
- Product
- 5-Amino-2,4,6-triiodoiso phthaloyl dichloride 37441-29-5
- Price
- US $90.90/Kg/Drum
- Min. Order
- 25Kg/Drum
- Purity
- 98.00%HPLC
- Supply Ability
- 2tons/month
- Release date
- 2021-09-23
- Product
- 5-Amino-2,4,6- Triiodisophthaloyl Acid Dichloride 37441-29-5
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2021-10-11