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5-INDANOL

Uses
Product Name
5-INDANOL
CAS No.
1470-94-6
Chemical Name
5-INDANOL
Synonyms
1H-Inden-5-ol, 2,3-dihydro-;2,3-Dihydro-1H-inden-5-ol;INDAN-5-OL;5-HYDROXYINDAN;5-HYDROXYINDANE;Indanol-5;5-INDANOL;5-INDANOL 99%;5-Indanol,99%;Indan-5-ol 98%
CBNumber
CB8210012
Molecular Formula
C9H10O
Formula Weight
134.18
MOL File
1470-94-6.mol
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5-INDANOL Property

Melting point:
51-53 °C (lit.)
Boiling point:
255 °C (lit.)
Density 
0.8540 (rough estimate)
refractive index 
1.5630 (estimate)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
6.3g/l
form 
powder to crystal
pka
10.37±0.20(Predicted)
color 
slightly brown
BRN 
1936314
CAS DataBase Reference
1470-94-6(CAS DataBase Reference)
EPA Substance Registry System
5-Indanol (1470-94-6)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
21-20/21/22
Safety Statements 
36/37-36
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
NK7525000
Hazard Note 
Irritant
HazardClass 
6.1
PackingGroup 
III
HS Code 
29062900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H311Toxic in contact with skin

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
I2215
Product name
5-Indanol
Purity
99%
Packaging
25g
Price
$58
Updated
2024/03/01
TCI Chemical
Product number
H0251
Product name
5-Hydroxyindan
Purity
>99.0%(GC)
Packaging
25g
Price
$87
Updated
2024/03/01
TCI Chemical
Product number
H0251
Product name
5-Hydroxyindan
Purity
>99.0%(GC)
Packaging
100g
Price
$264
Updated
2024/03/01
TRC
Product number
I499850
Product name
5-Indanol
Packaging
25g
Price
$250
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0027209
Product name
5-INDANOL
Purity
95.00%
Packaging
25G
Price
$1083.16
Updated
2021/12/16
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5-INDANOL Chemical Properties,Usage,Production

Uses

5-Indanol is a 5-hydroxyindole analog with weak inhibitory activity against human melanoma tyrosinase. 5-Indanol is also used as a reagent in the preparation of Sodium Indanylcarbinicillin; a compound which has been shown to reduce blood pressure in mammals and also has been used as a β-lactam antibiotic.

Description

5-Indanol, mp 54–55 ℃, bp 255 ℃, is produced from indan [496-11-7] by a sulfonation–alkali-fusion process. A synthesis for 1,1,3,3-tetraalkylindanols was developed by Bayer, which involves the reaction of isoolefins with secondary alkenylphenols (or compounds generating them under the reaction conditions) at 100–250 ℃ and in the presence of acidic catalysts. An example is the reaction of isobutene with bisphenol A in the presence of acid-activated clays which yields 1,1,3,3-tetramethyl-5-indanol [53718-26-6], mp 115 ℃, bp (2.66 kPa) 156 ℃, in a yield of 80% of the theoretical, and 4-tert-butylphenol as a coproduct.

Chemical Properties

light brown to grey-brown crystalline powder or

Uses

5-Indanol is a 5-hydroxyindole analog with weak inhibitory activity against human melanoma tyrosinase. 5-Indanol is also used as a reagent in the preparation of Sodium Indanylcarbinicillin (S635000); a compound which has been shown to reduce blood pressure in mammals and also has been used as a b-lactam antibiotic.

Definition

ChEBI: A member of the class of phenols that is indan which has been hydroxylated at position 5.

Purification Methods

Crystallise 5-hydroxyindane from pet ether (m 56o) or pentane (m 59-60o). It has UV with max at 283.5nm (cyclohexane). The 3,5-dinitrobenzoyl derivative has m 156o. [Beilstein 6 III 2428, 6 IV 3829.]

5-INDANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 5-INDANOL manufacturers

Henan Fengda Chemical Co., Ltd
Product
5-INDANOL 1470-94-6
Price
US $50.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-22
Career Henan Chemical Co
Product
5-Indanol 1470-94-6
Price
US $9.80/KG
Min. Order
1g
Purity
>98%
Supply Ability
20 tons
Release date
2020-02-10

1470-94-6, 5-INDANOLRelated Search:


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  • Indanol-5
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  • 5-INDANOL
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  • 5-HYDROXYINDAN
  • 1H-Inden-5-ol, 2,3-dihydro-
  • Indan-5-ol 98%
  • 2,3-Dihydro-1H-inden-5-ol
  • 5-HYDROXYINDANE
  • 5-INDANOLE 99+%
  • 5-INDANOL 99%
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