BRAZILIN
- Product Name
- BRAZILIN
- CAS No.
- 474-07-7
- Chemical Name
- BRAZILIN
- Synonyms
- razilin;BRAZILIN;CI 75280;brasilin;NSC 56652;braziletto;Brazilin-RM;(+)-Brazilin;Brazilin(6CI);superbresiline
- CBNumber
- CB9350126
- Molecular Formula
- C16H14O5
- Formula Weight
- 286.28
- MOL File
- 474-07-7.mol
BRAZILIN Property
- Melting point:
- 156-157℃
- Boiling point:
- 348.65°C (rough estimate)
- Density
- 1.1924 (rough estimate)
- refractive index
- 1.6200 (estimate)
- solubility
- DMSO:43.5(Max Conc. mg/mL);151.95(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);104.79(Max Conc. mM)
Ethanol:30.0(Max Conc. mg/mL);104.79(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);34.93(Max Conc. mM) - form
- A crystalline solid
- color
- Yellow to brown
- EPA Substance Registry System
- Brazilin (474-07-7)
Safety
- Safety Statements
- 24/25
- HS Code
- 29329990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SML2132
- Product name
- Brazilin
- Packaging
- 5MG
- Price
- $166
- Updated
- 2024/03/01
- Product number
- SML2132
- Product name
- Brazilin
- Packaging
- 25MG
- Price
- $246.6
- Updated
- 2024/03/01
- Product number
- 22456
- Product name
- Brazilin
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 22456
- Product name
- Brazilin
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $139
- Updated
- 2024/03/01
- Product number
- 22456
- Product name
- Brazilin
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $230
- Updated
- 2024/03/01
BRAZILIN Chemical Properties,Usage,Production
Description
Brazilin is an isoflavonoid originally isolated from C. sappan that has diverse biological activities, including neuroprotective, anti-inflammatory, antibacterial, and antioxidant properties. Brazilin inhibits Aβ (1-42) fibrillogenesis (IC50 = 1.5 μM) more potently than (-)-epigallocatechin gallate , cucurmin , and resveratrol (Item Nos. 10004235 | 70675). It also prevents remodeling of mature Aβ (1-42) fibrils. Brazilin inhibits the production of cytokines, including PGE2 and TNF-α (IC50s = 12.6 and 87.2 μM). It is effective against Gram-positive and Gram-negative bacteria with MICs ranging from 31.3 to 250 μg/ml. In addition, brazilin inhibits osteoclast differentiation mediated by RANKL and is protective against LPS-induced osteoporosis in mice at a dose of 100 mg/kg.
Uses
Brazilin is a hair dyeing composition that comprises a natural dye and fatty amine.
Uses
Chiefly as a dye. Has also been recommended as indicator in acid-base titrations; acids = yellow, alkalies = carmine-red.
Uses
inhibits platelet aggregation, PLA2, PKC, protein phosphatase, insulin receptor kinase, nitric oxide synthase, antineoplastic
Definition
ChEBI: A organic heterotetracyclic compound that is a red pigment obtained from the wood of Caesalpinia echinata (Brazil-wood) or Caesalpinia sappan (sappan-wood).
Purification Methods
Brazilin crystallises from EtOH as yellow crystals which become orange when exposed to light and air, and is yellow in dilute acid but crimson in dilute alkali. When crystallised from H2O, it has m 247-248o. It forms coloured metal salts and is oxidized in air to Brazilein the quinonoid form. The (±)-form has been resolved, and the (+)-enantiomer has [] 20 +121o (c 1, MeOH). [Craig et al. J Org Chem 30 1573 1965,Morsingh & Robinson Tetrahedron 26 281 1970, Beilstein 17 H 194, 17 II 244, 17 III/IV 2711.]
BRAZILIN Preparation Products And Raw materials
Raw materials
Preparation Products
BRAZILIN Suppliers
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View Lastest Price from BRAZILIN manufacturers
- Product
- BRAZILIN 474-07-7
- Price
- US $1.00-22.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100000KG
- Release date
- 2024-08-02
- Product
- Brazilin 474-07-7
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-12-12
- Product
- BRAZILIN 474-07-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27