BRAZILIN

Product Name: BRAZILIN
CAS No.: 474-07-7
Chemical Name: BRAZILIN
Synonyms: razilin;BRAZILIN;CI 75280;brasilin;NSC 56652;braziletto;Brazilin-RM;(+)-Brazilin;Brazilin(6CI);superbresiline
CBNumber: CB9350126
Molecular Formula: C16H14O5
Formula Weight: 286.28
MOL File: 474-07-7.mol

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BRAZILIN Property

Melting point:: 156-157℃
Boiling point:: 348.65°C (rough estimate)
Density: 1.1924 (rough estimate)
refractive index: 1.6200 (estimate)
solubility: DMSO:43.5(Max Conc. mg/mL);151.95(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);104.79(Max Conc. mM)
Ethanol:30.0(Max Conc. mg/mL);104.79(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);34.93(Max Conc. mM)
form: A crystalline solid
color: Yellow to brown
EPA Substance Registry System: Brazilin (474-07-7)

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Safety

Safety Statements: 24/25
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2132
Product name: Brazilin
Packaging: 5MG
Price: $166
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML2132
Product name: Brazilin
Packaging: 25MG
Price: $246.6
Updated: 2024/03/01

Cayman Chemical

Product number: 22456
Product name: Brazilin
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 22456
Product name: Brazilin
Purity: ≥98%
Packaging: 5mg
Price: $139
Updated: 2024/03/01

Cayman Chemical

Product number: 22456
Product name: Brazilin
Purity: ≥98%
Packaging: 10mg
Price: $230
Updated: 2024/03/01

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BRAZILIN Chemical Properties,Usage,Production

Description

Brazilin is an isoflavonoid originally isolated from C. sappan that has diverse biological activities, including neuroprotective, anti-inflammatory, antibacterial, and antioxidant properties. Brazilin inhibits Aβ (1-42) fibrillogenesis (IC₅₀ = 1.5 μM) more potently than (-)-epigallocatechin gallate , cucurmin , and resveratrol (Item Nos. 10004235 | 70675). It also prevents remodeling of mature Aβ (1-42) fibrils. Brazilin inhibits the production of cytokines, including PGE₂ and TNF-α (IC₅₀s = 12.6 and 87.2 μM). It is effective against Gram-positive and Gram-negative bacteria with MICs ranging from 31.3 to 250 μg/ml. In addition, brazilin inhibits osteoclast differentiation mediated by RANKL and is protective against LPS-induced osteoporosis in mice at a dose of 100 mg/kg.

Uses

Brazilin is a hair dyeing composition that comprises a natural dye and fatty amine.

Uses

Chiefly as a dye. Has also been recommended as indicator in acid-base titrations; acids = yellow, alkalies = carmine-red.

Uses

inhibits platelet aggregation, PLA2, PKC, protein phosphatase, insulin receptor kinase, nitric oxide synthase, antineoplastic

Definition

ChEBI: A organic heterotetracyclic compound that is a red pigment obtained from the wood of Caesalpinia echinata (Brazil-wood) or Caesalpinia sappan (sappan-wood).

Purification Methods

Brazilin crystallises from EtOH as yellow crystals which become orange when exposed to light and air, and is yellow in dilute acid but crimson in dilute alkali. When crystallised from H2O, it has m 247-248o. It forms coloured metal salts and is oxidized in air to Brazilein the quinonoid form. The (±)-form has been resolved, and the (+)-enantiomer has [] 20 +121o (c 1, MeOH). [Craig et al. J Org Chem 30 1573 1965,Morsingh & Robinson Tetrahedron 26 281 1970, Beilstein 17 H 194, 17 II 244, 17 III/IV 2711.]

BRAZILIN Preparation Products And Raw materials

Raw materials

Preparation Products

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BRAZILIN Suppliers

China 161 Germany 1 India 2 United Kingdom 4 United States 18 Global 186

Chengdu Herbpurify Co.Ltd.

Tel: 18302802153 18981717076
Fax: 086-28-85377358
Email: 2355253619@qq.com
Country: China
ProdList: 1104
Advantage: 58

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 19179
Advantage: 64

Shenzhen Sungening Bio-Tech Co., Ltd

Tel: +86-0755-89668383
Fax: +86-0755-89594066/4038
Email: sales@sungening.com
Country: China
ProdList: 1319
Advantage: 65

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4727
Advantage: 58

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 5653
Advantage: 65

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4940
Advantage: 60

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Chengdu Climax Biotech Co., Ltd.

Tel: 028-83311324 1278112614
Fax: 028-83311324
Email: climaxbiotech@gmail.com
Country: China
ProdList: 925
Advantage: 58

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View Lastest Price from BRAZILIN manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: BRAZILIN 474-07-7
Price: US $1.00-22.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100000KG
Release date: 2024-08-02

Shanghai Standard Technology Co., Ltd.

Product: Brazilin 474-07-7
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-12-12

Zhuozhou Wenxi import and Export Co., Ltd

Product: BRAZILIN 474-07-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

474-07-7, BRAZILINRelated Search:

Praeruptorin A Oridonin Praeruptorin B tuberostemonine Bilobalide Mangostin Curcumol BAVACHIN GARDENIN B 4',5-DIHYDROXY-7-METHOXYFLAVONE Peimine HEMATOXYLIN Hematoxylin BRAZILIN (+)-BRAZILIN--N/H PHOSPHOTUNGSTIC ACID HEMATOXYLIN LABOTEST-BB LT00441275 (+)-BRAZILIN

2-d)pyran-3,6a,9,10(6h)-tetrol,7,11b-dihydro-benz(b)indeno(

6a,9,10(6h)-tetrol,7,11b-dihydro-2-d]pyran-(6as-cis)-benz[b]indeno[

7,11b-dihydrobenz(b)indeno(1,2-d)pyran-3,6a,9,10(6h)-tetrol

brasilin

braziletto

hypernicextract

limawoodextract

pernambucoextract

BRAZILIN (C.I. 75280)

CI 75280

BRAZILIN

superbresiline

Benz[b]indeno[1,2-d]pyran-3,6a,9,10(6H)-tetrol,7,11b-dihydro-, (6aS,11bR)-

Brazilin, 98%, from Caesalpinia sappanL.

Brazilin(6CI)

enz[b]indeno[1,2-d]pyran-3,6a,9,10(6H)-tetrol,7,11b-dihydro-,(6aS-cis)-(7CI,8CI)

razilin

(6aS,11bR)-7,11b-Dihydrobenz[b]indeno[1,2-d]pyran-3,6a,9,10(6H)-tetrol

NSC 56652

7,11b-dihydroindeno[2,1-c]chromene-3,6a,9,10(6H)-tetrol

Brazilin >=98% (HPLC)

(+)-Brazilin

(6aS,11bR)-6,6a,7,11b-tetrahydroindeno[2,1-c]chromene-3,6a,9,10-tetraol

(6aS,11bR)-7,11b-Dihydroindeno[2,1-c]chromene-3,6a,9,10(6H)-tetraol

Brazilin-RM

Arginine Impurity 3 Hydrochloride (Arginine EP Impurity C Hydrochloride)(Ornithine Hydrochloride)

474-07-7

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract