ChemicalBook > CAS DataBase List > Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate

Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate

Product Name
Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
CAS No.
105228-46-4
Chemical Name
Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate
Synonyms
6-oxo-2;Benzyl (2S;3-diphenyl-;4-Morpholinecarboxylicacid;(2S,3R)-N-CBZ-6-OXO-2,3- DIPHENYLMORPHOLINE;(2S,3R)-(+)-N-Z-6-oxo-2,3-diphenylMorpholine;(2S,3R)-benzyl 6-oxo-2,3- diphenylmorpholine-4-carboxylate;(5S,6R)-(+)-4-Benzyloxycarbonyl-5,6-diphenyl-2-Morpholinone;(2S,3R)-(+)-N-Benzyloxycarbonyl-6-oxo-2,3-diphenylMorpholine;BENZYL (2S,3R)-(+)-6-OXO-2,3-DIPHENYL-4-MORPHOLINECARBOXYLATE
CBNumber
CB8215941
Molecular Formula
C24H21NO4
Formula Weight
387.43
MOL File
105228-46-4.mol
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Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Property

Melting point:
205-207 °C(lit.)
alpha 
66 º (c=5.5 in methylene chloride)
Boiling point:
583.5±50.0 °C(Predicted)
Density 
1.242±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
-3.33±0.60(Predicted)
Appearance
White to off-white Solid
optical activity
[α]25/D +66°, c = 5.5 in methylene chloride
InChI
InChI=1S/C24H21NO4/c26-21-16-25(24(27)28-17-18-10-4-1-5-11-18)22(19-12-6-2-7-13-19)23(29-21)20-14-8-3-9-15-20/h1-15,22-23H,16-17H2/t22-,23+/m1/s1
InChIKey
HECRUWTZAMPQOS-PKTZIBPZSA-N
SMILES
N1(C(OCC2=CC=CC=C2)=O)CC(=O)O[C@@H](C2=CC=CC=C2)[C@H]1C1=CC=CC=C1
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
HS Code 
29349990
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
331856
Product name
(2S,3R)-(+)-N-Z-6-oxo-2,3-diphenylmorpholine
Purity
99%
Packaging
1g
Price
$101
Updated
2023/06/20
TRC
Product number
B287520
Product name
(2S,3R)-Benzyl6-Oxo-2,3-diphenylmorpholine-4-carboxylate
Packaging
500mg
Price
$155
Updated
2021/12/16
ChemScene
Product number
CS-B0131
Product name
4-Morpholinecarboxylicacid,6-oxo-2,3-diphenyl-,phenylmethylester,(2S,3R)-
Packaging
1g
Price
$78
Updated
2021/12/16
Chem-Impex
Product number
41476
Product name
(2S,3R)-(+)-N-Z-6-oxo-2,3-diphenylmorpholine,≥98.5%(HPLC)
Purity
≥98.5%(HPLC)
Packaging
1G
Price
$88.52
Updated
2021/12/16
AK Scientific
Product number
1194AA
Product name
(2S,3R)-Benzyl6-oxo-2,3-diphenylmorpholine-4-carboxylate
Packaging
250mg
Price
$92
Updated
2021/12/16
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Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Chemical Properties,Usage,Production

Uses

(2S,3R)-(+)-N-Z-6-oxo-2,3-diphenylmorpholine can be used as a starting material for the synthesis of:

  • α-Amino-β-silyloxy-ester, a key intermediate for the preparation of antimalarial drug quinine and its analogs.
  • R, R-Formylglycine dimethylacetal, a key intermediate for the preparation of tuberculostatic compound capreomycin IB.
  • 2R,5R,6S-2-(Methoxycarbonylmethyl)-5,6-diphenylmorpholine hydrochloride, a key intermediate for the preparation of an antibiotic (+)-negamycin.

Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate Suppliers

China 66 Germany 1 India 1 Switzerland 1 United Kingdom 2 United States 15 Global 86
Tianjin Derchemist Science & Technology Co., Ltd.
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001-857-928-2050 or 1-888-588-9418
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View Lastest Price from Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate manufacturers

Career Henan Chemical Co
Product
Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate 105228-46-4
Price
US $6.68/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2020-01-09

105228-46-4, Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylateRelated Search:

Moroxydine Moroxydine hydrochloride Biphenyl Benzyl isocyanate Benzyl benzoate Tridemorph Benzyl nicotinate Benzyl alcohol Benzyl chloride Dimethomorph Benzyl (+)-N-METHYLEPHEDRINE (S)-(-)-N-(2-HYDROXYETHYL)-ALPHA-PHENYLETHYLAMINE Z-SAR-OH 5-Phenyl-2-morpholinone D-(+)-Norephedrine BENZYL (2R,3S)-(-)-6-OXO-2,3-DIPHENYL-4-MORPHOLINECARBOXYLATE N-ISOPROPYL-N-METHYLGLYCINE

  • BENZYL (2S,3R)-(+)-6-OXO-2,3-DIPHENYL-4-MORPHOLINECARBOXYLATE
  • (2S,3R)-benzyl 6-oxo-2,3- diphenylmorpholine-4-carboxylate
  • 4-Morpholinecarboxylic acid, 6-oxo-2,3-diphenyl-, phenylmethyl ester, (2S,3R)-
  • 3-diphenyl-
  • 4-Morpholinecarboxylicacid
  • 6-oxo-2
  • (2S,3R)-(+)-N-Z-6-oxo-2,3-diphenylMorpholine
  • (5S,6R)-(+)-4-Benzyloxycarbonyl-5,6-diphenyl-2-Morpholinone
  • (2S,3R)-(+)-N-Benzyloxycarbonyl-6-oxo-2,3-diphenylMorpholine
  • (5R,6S)-4-(benzyloxycarbonyl)-5,6-diphenyl-2,3,5,6-tetrahydro-4H-1,4-oxazin-2-one
  • (2<I>S</I>,3<I>R</I>)-(+)-<I>N</I>-<WBR>Z-<WBR>6-<WBR>oxo-<WBR>2,3-<WBR>diphenylMorpholine
  • (2S,3R)-N-CBZ-6-OXO-2,3- DIPHENYLMORPHOLINE
  • Benzyl (2S
  • Benzyl (2S,3R)-6-Oxo-2,3-diphenyl-4-morpholinecarbox ylate,99%e.e.
  • (2S,3R)-6-oxo-2,3-diphenyl-4-morpholinecarboxylic acid (phenylmethyl) ester
  • (2<i>S</i>,3<i>R</i>)-(+)-<i>N</i>-Z-6-oxo-2,3-diphenylmorpholine
  • 105228-46-4
  • Chiral Building Blocks
  • Asymmetric Synthesis
  • Morpholines
  • Heterocyclic Building Blocks
  • Chiral Building Blocks
  • Heterocyclic Building Blocks
  • Morpholines