ChemicalBook > CAS DataBase List > 2,4-Difluorobenzyl bromide

2,4-Difluorobenzyl bromide

Product Name: 2,4-Difluorobenzyl bromide
CAS No.: 23915-07-3
Chemical Name: 2,4-Difluorobenzyl bromide
Synonyms: 1-(bromomethyl)-2,4-difluorobenzene;TIMTEC-BB SBB006567;2,4-Difluorobenzyl b;4-Difluorobenzyl broMide;2,4-DIFLUOROBENZYL BROMID;2,4-DIFLUOROBENZYL BROMIDE;2,4-Difluoro Bromine Benzyl;à-bromo-2,4-difluorotoluene;α-bromo-2,4-difluorotoluene;a-Bromo-2,4-difluorotoluene
CBNumber: CB8220095
Molecular Formula: C7H5BrF2
Formula Weight: 207.02
MOL File: 23915-07-3.mol

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2,4-Difluorobenzyl bromide Property

Melting point:: 18 °C
Boiling point:: 28 °C
Density: 1.613 g/mL at 25 °C(lit.)
refractive index: n20/D 1.525(lit.)
Flash point:: 104 °F
storage temp.: Inert atmosphere,2-8°C
form: Liquid
Specific Gravity: 1.63
color: Clear yellow
Sensitive: Lachrymatory
BRN: 4177539
CAS DataBase Reference: 23915-07-3(CAS DataBase Reference)

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Safety

Hazard Codes: C,F
Risk Statements: 10-34-42/43-36
Safety Statements: 23-26-36/37/39-45-25-16
RIDADR: UN 2920 8/PG 2
WGK Germany: 3
Hazard Note: Corrosive/Lachrymatory
HazardClass: 8
PackingGroup: III
HS Code: 29039990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 264415
Product name: 2,4-Difluorobenzyl bromide
Purity: 98%
Packaging: 5g
Price: $46.5
Updated: 2023/01/07

Sigma-Aldrich

Product number: 264415
Product name: 2,4-Difluorobenzyl bromide
Purity: 98%
Packaging: 25g
Price: $125
Updated: 2023/01/07

TCI Chemical

Product number: B1710
Product name: 2,4-Difluorobenzyl Bromide
Purity: >98.0%(GC)
Packaging: 5g
Price: $56
Updated: 2025/07/31

TCI Chemical

Product number: B1710
Product name: 2,4-Difluorobenzyl Bromide
Purity: >98.0%(GC)
Packaging: 25g
Price: $222
Updated: 2025/07/31

TRC

Product number: D447555
Product name: 2,4-Difluorobenzyl bromide
Packaging: 10g
Price: $165
Updated: 2021/12/16

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2,4-Difluorobenzyl bromide Chemical Properties,Usage,Production

Chemical Properties

CLEAR YELLOW LIQUID

Uses

2,4-Difluorobenzyl bromide has been used in the preparation of:

novel 1,2,4-triazolium derivatives
1,5-biaryl pyrrole EP₁ receptor antagonists

Synthesis

56456-47-4

23915-07-3

The general procedure for the synthesis of 2,4-difluorobenzyl bromide from 2,4-difluorobenzyl alcohol was as follows: to a solution of diethyl ether (10 mL) of 2,4-difluorobenzyl alcohol (450 mg, 3.12 mmol) was slowly added phosphorus tribromide (0.2 mL, 2.18 mmol) at 0 °C. The reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction (monitored by thin layer chromatography), the reaction was quenched with ice water (20 mL) and extracted with ethyl acetate (2 x 20 mL). The organic layers were combined, washed sequentially with water (40 mL) and saturated saline (40 mL), dried over anhydrous sodium sulfate, and concentrated under reduced pressure to give the crude product. Purification by silica gel column chromatography with 5% ethyl acetate/hexane as eluent gave 2,4-difluorobenzyl bromide (420 mg, 2.02 mmol, 65% yield) as a colorless liquid.1H NMR (200 MHz, CDCl3): δ 7.43-7.31 (m, 1H), 6.92-6.77 (m, 2H), 4.48 (s, 2H).

References

[1] Patent: US2012/329788, 2012, A1. Location in patent: Page/Page column 26

2,4-Difluorobenzyl bromide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,4-Difluorobenzyl bromide manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 2,4-Difluorobenzyl bromide 23915-07-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-06-06

Henan Fengda Chemical Co., Ltd

Product: 2,4-Difluorobenzyl bromide 23915-07-3
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-25

Career Henan Chemical Co

Product: 2,4-Difluorobenzyl bromide 23915-07-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-06-25

23915-07-3, 2,4-Difluorobenzyl bromideRelated Search:

Benzyltriethylammonium chloride Decabromodiphenyl Ethane Dibenzyl disulfide Ethyl bromodifluoroacetate Rocuronium bromide 1,2-Difluorobenzene Allyl bromide Sodium bromate Bromofluoromethane Benzyl bromide Ethidium bromide Dibenzylideneacetone alpha-Chloro-o-fluorotoluene BENDROFLUMETHIAZIDE Benzyl chloride 4-CHLORO-2-TRICHLOROMETHYL-QUINOLINE Methyl bromide 2,3-Difluorobenzyl bromide 98%,2,3-DIFLUOROBENZYL BROMIDE

4-Difluorobenzyl broMide

alpha-BroMo-2,4-difluorotoluene, 98% 5GR

ALPHA-BROMO-2,4-DIFLUOROTOLUENE

Toluene, α-broMo-2,4-difluoro- (8CI)

1-(Bromomethyl)-2,4-difluorobenzene, alpha-Bromo-2,4-difluorotoluene

2,4-Difluorobenzyl broMide 98%, 4-Difluorobenzyl broMide 98%

2,4-DIFLUOROBENZYL BROMIDE

2,4-Difluoro Bromine Benzyl

TIMTEC-BB SBB006567

1-(bromomethyl)-2,4-difluorobenzene

2,4-DIFLUOROBENZYL BROMID

Benzene, 1-(bromomethyl)-2,4-difluoro-

à-bromo-2,4-difluorotoluene

α-bromo-2,4-difluorotoluene

a-Bromo-2,4-difluorotoluene

2,4-Difluorobenzylbromide,98%

alpha-Bromo-2,4-difluorotoluene,98%

2,4-Difluorobenzyl bromide,α-Bromo-2,4-difluorotoluene

2,4-Difluorobenzyl b

2,4-Difluorobenzyl Bromide &gt

2,4-Difluorobenzyl bromide ISO 9001：2015 REACH

23915-07-3

BENZYL HALIDE

Aryl

Building Blocks

Halogenated Hydrocarbons

Organic Building Blocks

Aromatic Halides (substituted)

Benzene series

Miscellaneous

Fluorinated benzene series

Fluoro-contained benzyl bromide series

Fluorine series