ChemicalBook > CAS DataBase List > 5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium
5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium
- Product Name
- 5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium
- CAS No.
- 54260-72-9
- Chemical Name
- 5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium
- Synonyms
- 13-Methylberberine;13-Methylberberinium Chlorid;13-Methylberberine (chloride);13-methylberberine/13-Methylberberine chloride;2,3-(Methylenedioxy)-9,10-dimethoxy-13-methyl-5H,6H-dibenzo[a,g]quinolizin-7-ium;9,10-Dimethoxy-13-methyl-5,6-dihydrobenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium;5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium;9,10-Dimethoxy-13-methyl-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium chloride;inhibit,Inhibitor,13 Methylberberine chloride,13Methylberberine chloride,Interleukin Related,13-Methylberberinium
- CBNumber
- CB82266822
- Molecular Formula
- C21H20ClNO4
- Formula Weight
- 385.8408
- MOL File
- 54260-72-9.mol
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5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium Property
- Melting point:
- 198-200 °C
- storage temp.
- Store at -20°C
- solubility
- Water: 1 mg/ml
- form
- A crystalline solid
- color
- Light yellow to yellow
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 21154
- Product name
- 13-Methylberberine (chloride)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $54
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21154
- Product name
- 13-Methylberberine (chloride)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $231
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 21154
- Product name
- 13-Methylberberine (chloride)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $410
- Updated
- 2024/03/01
AK Scientific
- Product number
- 0436CB
- Product name
- 5,6-Dihydro-9,10-dimethoxy-13-methylbenzo(g)-1,3-benzodioxolo(5,6-a)quinoliziniumchloride
- Packaging
- 5mg
- Price
- $355
- Updated
- 2021/12/16
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5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium Chemical Properties,Usage,Production
Description
13-Methylberberine (13-MB) (chloride) is a 13-methyl-substituted derivative of berberine . Berberine is a widely distributed berberidaceaen alkaloid found in plant tissues that has antibacterial, anti-inflammatory, antitumor, anti-obesity, and hypercholesterolemic activity. 13-MB has improved antibacterial activity against S. aureus (MIC = 125 μg/ml) and improved antitumor activity with a mean GI50 value of 11.7 μM, as compared to berberine. 13-MB also induces down-regulation of adipocyte differentiation transcription factors, reduces de novo lipid synthesis, and accumulates in murine 3T3-L1 adipocytes at higher levels than berberine, suggesting improved anti-obesity activity.
Uses
13-Methylberberinium Chloride can be used to treat and prevent immunoinflammatory dermal disorders. It can also be used in synthesis to result in derivatives that can be used to treat nerve diseases and anti-infective agents.
5,6-Dihydro-2,3-(methylenedioxy)-9,10-dimethoxy-13-methyldibenzo[a,g]quinolizinium Preparation Products And Raw materials
Raw materials
Preparation Products
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