ChemicalBook > CAS DataBase List > Veraphenol

Veraphenol

Product Name
Veraphenol
CAS No.
56317-21-6
Chemical Name
Veraphenol
Synonyms
Moracin M;Veraphenol;Sancinsol M;Moracin M, 10 mM in DMSO;6,3',5'-Trihydroxy-2-phenylbenzofuran;2-(3,5-Dihydroxyphenyl)benzofuran-6-ol;2-(3,5-Dihydroxyphenyl)-6-hydroxybenzofuran;5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol;1,3-Benzenediol, 5-(6-hydroxy-2-benzofuranyl)-;5-(6-hydroxy-1-benzofuran-2-yl)benzene-1,3-diol
CBNumber
CB82268725
Molecular Formula
C14H10O4
Formula Weight
242.23
MOL File
56317-21-6.mol
More
Less

Veraphenol Property

Melting point:
271-273℃
Boiling point:
369.3±22.0 °C(Predicted)
Density 
1.451±0.06 g/cm3(Predicted)
storage temp. 
4°C, protect from light
solubility 
DMSO: 16.67 mg/mL (68.82 mM)
form 
Powder
pka
9.05±0.40(Predicted)
color 
Off-white to light yellow
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

TRC
Product number
M482900
Product name
MoracinM
Packaging
100mg
Price
$1260
Updated
2021/12/16
ChemScene
Product number
CS-0090595
Product name
MoracinM
Purity
98.50%
Packaging
100mg
Price
$980
Updated
2021/12/16
ChemScene
Product number
CS-0090595
Product name
MoracinM
Purity
98.50%
Packaging
10mg
Price
$160
Updated
2021/12/16
ChemScene
Product number
CS-0090595
Product name
MoracinM
Purity
98.50%
Packaging
50mg
Price
$580
Updated
2021/12/16
Crysdot
Product number
CD32000974
Product name
MoracinM
Purity
95+%
Packaging
5mg
Price
$730
Updated
2021/12/16
More
Less

Veraphenol Chemical Properties,Usage,Production

Uses

Moracin M is a tyrosinase inhibitory polyphenols from roots of Morus Alba. It also showed hypoglycemic effect by reducing glucose levels and lipid peroxidation and increasing insulin levels in rats with streptozotocin-induced diabetes mellitus.

Definition

ChEBI: Moracin M is a member of benzofurans.

Synthesis Reference(s)

Tetrahedron Letters, 28, p. 2645, 1987 DOI: 10.1016/S0040-4039(00)96171-9

in vivo

Moracin M (20, 60 mg/kg, Oral gavage) reduces inflammatory response in LPS (HY-D1056) -induced acute lung injury (ALI) mouse models, decreases the total number of infiltrated cells in bronchoalveolar lavage (BAL) fluid, and significantly reduces the number of neutrophils, macrophages and dendritic cells[2].
Moracin M (20, 60 mg/kg, Oral gavage) alleviates pathological changes in lung tissue in ALI mouse models, including reduces alveolar wall thickness, increases alveolar space, and reduces inflammatory cell infiltration in lung tissue[2].
Moracin M (20, 60 mg/kg, Oral gavage) significantly inhibits NF-κB activation in the lungs in a mouse model of ALI[2].

Animal Model:LPS-induced acute lung injury (ALI) mouse models[2]
Dosage:LPS (HY-D1056) 2 mg/kg; LPS 2 mg/kg+ Moracin M 20 mg/kg, 60 mg/kg; LPS 2 mg/kg+ Dexamethasone (HY-14648) 30 mg/kg. (n=13)
Administration:Oral gavage
Result:Reduced the inflammatory response in ALI mouse models and reduced the total number of cells infiltrated in bronchoalveolar lavage (BAL) fluid. The number of neutrophils, macrophages and dendritic cells was significantly decreased.
Reduced the thickness of alveolar wall, increasing alveolar space, and reduced the infiltration of inflammatory cells in lung tissue.

target

PDE

IC 50

PDE4D2: 2.9 μM (IC50); PDE4B2: 4.5 μM (IC50); PDE5A1: >40 μM (IC50); PDE9A2: >100 μM (IC50)

Veraphenol Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Veraphenol Suppliers

China 84 United States 6 Global 90
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5645
Advantage
65
Sichuan Wei Keqi Biological Technology Co., Ltd.
Tel
028-81700200 18116577057
Fax
028-81705658
Email
3003855609@qq.com
Country
China
ProdList
7778
Advantage
56
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Wuhan ChemFaces Biochemical Co., Ltd.
Tel
18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
Country
China
ProdList
6905
Advantage
55
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Shanghai ChengShao Biological Technology Co., Ltd.
Tel
021-61847300 13341622919
Fax
021-61847300
Email
shcss01@163.com
Country
China
ProdList
4808
Advantage
58
Shanghai Rechem science Co., Ltd.
Tel
021-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2991
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9125
Advantage
58
Shanghai SuperLan Chemcial Technique Centre
Tel
0-2022843681 15618226720
Fax
+86-21-51601218
Email
chaolaichem@foxmail.com
Country
China
ProdList
10410
Advantage
58

56317-21-6, VeraphenolRelated Search:

M2 H-AP53 Primer (2 &micro 2-Amino-4-chloro-6-methylpyrimidine beta-Sitosterol beta-Eudesmol alpha-Terpineol 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one MOSLOFLAVONE alpha-Cyperone (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one Artemether hydroxygenkwanin Hydroxyecdysone

  • 2-(3,5-Dihydroxyphenyl)benzofuran-6-ol
  • Moracin M
  • Veraphenol
  • 2-(3,5-Dihydroxyphenyl)-6-hydroxybenzofuran
  • 6,3',5'-Trihydroxy-2-phenylbenzofuran
  • 5-(6-hydroxy-1-benzofuran-2-yl)benzene-1,3-diol
  • 1,3-Benzenediol, 5-(6-hydroxy-2-benzofuranyl)-
  • 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol
  • Sancinsol M
  • Moracin M, 10 mM in DMSO
  • 56317-21-6