1-Ethenyl-4-methoxy-9H-pyrido[3,4-b]indol-8-ol

Product Name: 1-Ethenyl-4-methoxy-9H-pyrido[3,4-b]indol-8-ol
CAS No.: 100234-59-1
Chemical Name: 1-Ethenyl-4-methoxy-9H-pyrido[3,4-b]indol-8-ol
Synonyms: Picrasidine I;4-Methoxy-1-vinyl-9H-β-carbolin-8-ol;1-Ethenyl-4-methoxy-9H-pyrido[3,4-b]indol-8-ol;9H-Pyrido[3,4-b]indol-8-ol,1-ethenyl-4-methoxy-
CBNumber: CB82310369
Molecular Formula: C14H12N2O2
Formula Weight: 240.26
MOL File: 100234-59-1.mol

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1-Ethenyl-4-methoxy-9H-pyrido[3,4-b]indol-8-ol Property

Boiling point:: 528.2±45.0 °C(Predicted)
Density: 1.352±0.06 g/cm3(Predicted)
pka: 9.38±0.30(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom

Product number: CFN99019
Product name: PicrasidineI
Purity: ≥98%
Packaging: 5mg
Price: $368
Updated: 2021/12/16

Crysdot

Product number: CD32003000
Product name: PicrasidineI
Purity: 95+%
Packaging: 5mg
Price: $930
Updated: 2021/12/16

AccelPharmtech

Product number: P4981
Product name: 1-ethenyl-4-methoxy-9H-Pyrido[3,4-b]indol-8-ol
Purity: 97.00%
Packaging: 1G
Price: $3120
Updated: 2021/12/16

AccelPharmtech

Product number: P4981
Product name: 1-ethenyl-4-methoxy-9H-Pyrido[3,4-b]indol-8-ol
Purity: 97.00%
Packaging: 5G
Price: $5360
Updated: 2021/12/16

AccelPharmtech

Product number: P4981
Product name: 1-ethenyl-4-methoxy-9H-Pyrido[3,4-b]indol-8-ol
Purity: 97.00%
Packaging: 25G
Price: $13300
Updated: 2021/12/16

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1-Ethenyl-4-methoxy-9H-pyrido[3,4-b]indol-8-ol Chemical Properties,Usage,Production

Uses

Picrasidine I is an anti-inflammatory and anti-osteoclastogenic dimeric alkaloid that can be isolated from Picrasma quassioides. Picrasidine I inducs cell cycle arrest, and triggers cell apoptosis by downregulats ERK and Akt pathways. Picrasidine I inhibits the activation of MAPKs, NF-κB and ROS generation, and suppresses the expression of c-Fos and NFATc1[1][2].

References

[1] Ho HY, et al. Picrasidine I Triggers Heme Oxygenase-1-Induced Apoptosis in Nasopharyngeal Carcinoma Cells via ERK and Akt Signaling Pathways. Int J Mol Sci. 2022 May 29;23(11):6103. DOI:10.3390/ijms23116103
[2] Kong L, et al. Picrasidine I from Picrasma Quassioides Suppresses Osteoclastogenesis via Inhibition of RANKL Induced Signaling Pathways and Attenuation of ROS Production. Cell Physiol Biochem. 2017;43(4):1425-1435. DOI:10.1159/000481874

1-Ethenyl-4-methoxy-9H-pyrido[3,4-b]indol-8-ol Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Ethenyl-4-methoxy-9H-pyrido[3,4-b]indol-8-ol Suppliers

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1-Ethenyl-4-methoxy-9H-pyrido[3,4-b]indol-8-ol

Picrasidine I

9H-Pyrido[3,4-b]indol-8-ol,1-ethenyl-4-methoxy-

4-Methoxy-1-vinyl-9H-β-carbolin-8-ol

100234-59-1