ChemicalBook > CAS DataBase List > 13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one

13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one

Product Name: 13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one
CAS No.: 548-30-1
Chemical Name: 13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one
Synonyms: Oxysanguinarine;Oxosanguinarine;8-Oxosanguinarine;Hydroxysanguinarine;Colistin Sulfate Impurity 3;13-Methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-14(13H)-one;13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one;[1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-14(13H)-one, 13-methyl-;13-Methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridin-14(13H)-one;antimalarial,resistant,Parasite,inhibit,Plasmodium,Oxysanguinarine,falciparum strain,Inhibitor
CBNumber: CB82321839
Molecular Formula: C20H13NO5
Formula Weight: 347.32
MOL File: 548-30-1.mol

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13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one Property

Melting point:: 223-224 °C
Boiling point:: 628.7±55.0 °C(Predicted)
Density: 1.509±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
form: Solid
pka: -1.58±0.20(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0134941
Product name: Oxysanguinarine
Packaging: 1mg
Price: $120
Updated: 2021/12/16

Arctom

Product number: CFN91002
Product name: Oxysanguinarine
Packaging: 10mg
Price: $268
Updated: 2021/12/16

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13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one Chemical Properties,Usage,Production

Description

An a-naphthaphenanthridine alkaloid, this base occurs in the roots of Sanguinaria canadensis. It is separated from the remaining bases by chromatography and purified by crystallization from CHC13 followed by sublimation in a high vacuum. It is optically inactive and may also be prepared by oxidation of sanguinarine nitrate by potassium ferricyanide in alkaline solution. No salts of this alkaloid have been prepared.

Uses

Hydroxysanguinarine can be used to treat coronavirus infection.

Definition

ChEBI: Hydroxysanguinarine is a benzophenanthridine alkaloid.

IC 50

Plasmodium

References

Spiithetal., Ber., 70, 1677 (1936)
Schlemmer, Gempp., Arch. Pharm., 276,506 (1938)

13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

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548-30-1, 13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-oneRelated Search:

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13-Methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine-14(13H)-one

13-Methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-14(13H)-one

Oxosanguinarine

Oxysanguinarine

Hydroxysanguinarine

[1,3]Benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridin-14(13H)-one, 13-methyl-

8-Oxosanguinarine

13-Methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridin-14(13H)-one

antimalarial,resistant,Parasite,inhibit,Plasmodium,Oxysanguinarine,falciparum strain,Inhibitor

Colistin Sulfate Impurity 3

548-30-1