Description References
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D-alpha-Cyclohexylglycine

Description References
Product Name
D-alpha-Cyclohexylglycine
CAS No.
14328-52-0
Chemical Name
D-alpha-Cyclohexylglycine
Synonyms
D-CHG;D-αD-CHG-OH;H-D-CHG-OH;D-Chg-OH·TFA;H-D-CHG-OH TFA;-Hydrazino-αD-Cyclohexyglycine;D-CYCLOHEXYLGLYCINE;H-PHG(HEXAHYDRO)-OH
CBNumber
CB8234915
Molecular Formula
C8H15NO2
Formula Weight
157.21
MOL File
14328-52-0.mol
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D-alpha-Cyclohexylglycine Property

Melting point:
256 °C
alpha 
-34.5 º (c=0.4 5N HCl)
Boiling point:
292.8±23.0 °C(Predicted)
Density 
1.120±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
DMSO
pka
2.44±0.10(Predicted)
form 
Solid
color 
Off-White
Water Solubility 
Soluble
BRN 
3196806
InChIKey
WAMWSIDTKSNDCU-SSDOTTSWSA-N
CAS DataBase Reference
14328-52-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26-24/25
WGK Germany 
3
HS Code 
29224999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
61844
Product name
D-α-Cyclohexylglycine
Purity
≥98.0% (HPLC)
Packaging
5G
Price
$270
Updated
2024/03/01
TCI Chemical
Product number
C2673
Product name
D-2-Cyclohexylglycine
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$106
Updated
2024/03/01
Alfa Aesar
Product number
H63381
Product name
D-(-)-2-Cyclohexylglycine, 95%
Packaging
1g
Price
$34.65
Updated
2024/03/01
Alfa Aesar
Product number
H63381
Product name
D-(-)-2-Cyclohexylglycine, 95%
Packaging
5g
Price
$133.65
Updated
2024/03/01
Alfa Aesar
Product number
H63381
Product name
D-(-)-2-Cyclohexylglycine, 95%
Packaging
25g
Price
$470
Updated
2021/12/16
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D-alpha-Cyclohexylglycine Chemical Properties,Usage,Production

Description

D-alpha-Cyclohexylglycine is a kind of non-proteinogenic amino acid. It is widely presented in various natural products and pharmaceutical intermediates. It can be incorporated into the peptide inhibitors renders resistance from peptidases and proteinases and thereby imparts pharmacological stability to molecules. Some derivatives of Cyclohexylglycine has been recently been developed into inhibitors of the dipeptidyl peptidase-IV enzyme (“DP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes.

References

https://www.qmbio.com/?shopp_category=chg
Edmondson, Scott D., A. Mastracchio, and E. R. Parmee. "CYCLOHEXYLGLYCINE DERIVATIVES AS DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES." (2008).
Mastracchio, Anthony, et al. "Heterocycle-Fused Cyclohexylglycine Derivatives as Novel Dipeptidyl Peptidase-IV Inhibitors. " Cheminform 35.35(2004):203-206.

Chemical Properties

white powder

Uses

D-Cyclohexylglycine (cas# 14328-52-0) is a compound useful in organic synthesis.

reaction suitability

reaction type: solution phase peptide synthesis

D-alpha-Cyclohexylglycine Preparation Products And Raw materials

Raw materials

Preparation Products

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D-alpha-Cyclohexylglycine Suppliers

Carbosynth
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United Kingdom
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CMS Chemicals Limited
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CARBONE SCIENTIFIC CO.,LTD
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ETA SCIENTIFIC Co.,Ltd
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United Kingdom
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UK GREEN SCIENTIFIC CO.,LIMITED
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Eurolabs Limited
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Fluorochem Ltd
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United Kingdom
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Fluorochem Ltd.
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United Kingdom
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View Lastest Price from D-alpha-Cyclohexylglycine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
D-alpha-Cyclohexylglycine 14328-52-0
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
1000kg
Release date
2021-08-31
Honest Joy Holdings Limited
Product
D-Cyclohexylglycine 14328-52-0
Price
US $0.00/KG
Min. Order
1KG
Purity
97.8%
Supply Ability
100 tons
Release date
2022-01-26
Sichuan Jiaying Lai Technology Co.,LTD
Product
D-Chg-OH 14328-52-0
Price
US $1.00/g
Min. Order
1g
Purity
98%
Supply Ability
100KG
Release date
2019-07-23

14328-52-0, D-alpha-CyclohexylglycineRelated Search:


  • D-CHG-OH
  • D-&alpha
  • (R)-2-Cyclohexylglycine
  • D-α-AMinocyclohexaneacetic Acid
  • D-Chg-OH·TFA
  • D-Cyclohexylglycine,99%e.e.
  • (R)-CYCLOHEXYLGLYCINE
  • (R)-AMINO-CYCLOHEXYL-ACETIC ACID
  • (R)-(+)-ALPHA-AMINOCYCLOHEXYLACETIC ACID
  • (R)-ALPHA-AMINOCYCLOHEXYLACETIC ACID
  • D-CYCLOHEXYLGLYCINE
  • D-CHG
  • D-2-CYCLOHEXYL-GLYCINE
  • D-2-CYCLOHEXYLGLYCINE TRIFLUOROACETATE
  • D-ALPHA-CYCLOHEXYLGLYCINE
  • CYCLOHEXYL-D-GLYCINE
  • H-PHG(HEXAHYDRO)-OH
  • H-D-CHG-OH
  • H-D-CHG-OH TFA
  • H-CYCLOHEXYL-D-GLY-OH
  • H-CYCLOHEXYL-D-GLY-OH TFA
  • 2-CYCLOHEXYL-D-GLYCINE
  • H-D-Cyclohexyl-Gly-OH
  • D-Cyclohexyglycine
  • (2S)-amino(cyclohexyl)acetic acid
  • D-CYCLOHEXYLGLYCINE 98%
  • (R)-2-amino-2-cyclohexylaceticacid
  • D-alpha-Cyclohexylglycine,98%
  • D-α-Cyclohexylglycine, 98.0%
  • -Bromocamphor-8-sulfonic Acid Ammonium Salt
  • -(3,4-dihydroxyphenyl)propionic Acid (Mixture of Diasteromers)
  • -Hydrazino-&alpha
  • D-2-Cyclohexylglycine &gt
  • Cyclohexaneacetic acid, α-amino-, (αR)-
  • D-α-Cyclohexylglycine
  • D-alpha-Cyclohexylglycine USP/EP/BP
  • D-α-Aminocyclohexylacetic acid
  • D-alpha-Cyclohexylglycine 14328-52-0
  • (αR)-α-Aminocyclohexaneacetic acid
  • 14328-52-0
  • C8H15NO2C2HF3O2
  • Glycine Derivatives
  • Specialty Synthesis
  • Peptide Synthesis
  • Unnatural Amino Acid Derivatives
  • Amino Acids & Derivatives
  • Chiral Reagents
  • Miscellaneous Reagents
  • Peptide