ChemicalBook > CAS DataBase List > 11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE

Product Name
11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE
CAS No.
641-77-0
Chemical Name
11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE
Synonyms
21-deoxycortisol;C05497;Desoxycortisol;21-DESOXYCORTISOL;Azlocillin Impurity 7;21-Deoxyhydrocortisone;Hydrocortisone EP IMP L;21-Dehydrohydrocortisone;21-Deoxycortisol solution;Hydrocortisone Impurity L
CBNumber
CB8236919
Molecular Formula
C21H30O4
Formula Weight
346.46
MOL File
641-77-0.mol
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11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE Property

Melting point:
225-228 °C
Boiling point:
523.9±50.0 °C(Predicted)
Density 
1.21±0.1 g/cm3(Predicted)
Flash point:
9℃
storage temp. 
-20°C
solubility 
Chloroform (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
12.86±0.70(Predicted)
color 
White to Pale Yellow
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Safety

Hazard Codes 
F,T
Risk Statements 
11-23/24/25-39/23/24/25
Safety Statements 
7-16-36/37-45
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P311Call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P9521
Product name
21-Deoxycortisol
Packaging
25mg
Price
$435
Updated
2024/03/01
Sigma-Aldrich
Product number
D-062
Product name
21-Deoxycortisol solution
Purity
100?μg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
Packaging
1mL
Price
$142
Updated
2024/03/01
Cayman Chemical
Product number
30873
Product name
21-Deoxycortisol
Packaging
1mg
Price
$45
Updated
2024/03/01
Cayman Chemical
Product number
30873
Product name
21-Deoxycortisol
Packaging
5mg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
30873
Product name
21-Deoxycortisol
Packaging
10mg
Price
$220
Updated
2024/03/01
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11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

21-Deoxy Cortisol (Hydrocortisone EP Impurity L) is a metabolite of Fluticasone propionate (F599500).

Uses

A metabolite of Fluticasone propionate (F599500).

Definition

ChEBI: 21-deoxycortisol is a deoxycortisol that is 17xi-pregn-4-ene-3,20-dione substituted by a beta-hydroxy group at position 11 and an alpha-hydroxy group at position 17. It is a marker of virilizing adrenal hyperplasia caused by 21-hydroxylase deficiency. It has a role as a human blood serum metabolite and a mouse metabolite. It is an 11beta-hydroxy steroid, a 17alpha-hydroxy-C21-steroid, a tertiary alpha-hydroxy ketone and a deoxycortisol.

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE Suppliers

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641-77-0, 11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONERelated Search:

6-Dehydrocortisol 11beta,17,21-trihydroxypregn-4-ene-3,20-dione 17-acetate 6 beta-hydroxycortisol 9beta,11beta-epoxy-17,21-dihydroxypregn-4-ene-3,20-dione Hydrocortisone Hydrocortisone acetate Hydrocortisone-17-butyrate Hydrocortisone 21-hemisuccinate 6BETA-HYDROXYCORTISOL Hydrocortisone sodium succinate Flurandrenolide CORTISOL 17-VALERATE Hydrocortisone sodium phosphate 11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE 4-PREGNENE-11BETA,17ALPHA,21-TRIOL-3,20-DIONE 21-CAPRYLATE HYDROCORTISONE CYPIONATE (200 MG) 4-PREGNEN-6-ALPHA, 11-BETA, 17,21-TETROL-3,20-DIONE ACETATE 4-PREGNEN-11-BETA, 17,21-TRIOL-3,20-DIONE 21-GLUCOSIDURONATE

  • 21-deoxycortisol
  • 21 DEOXYCORTISOL 21-DESOXYCORTISOL
  • 21-DESOXYCORTISOL
  • 11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE
  • 11BETA,17ALPHA-DIHYDROXY-PROGESTERONE
  • 4-PREGNENE-11BETA,17ALPHA-DIOL-3,20-DIONE
  • 4-PREGNEN-11BETA,17ALPHA-DIOL-3,20-DIONE
  • 4-PREGNEN-11-BETA, 17-DIOL-3,20-DIONE
  • 11-beta,17-alpha-dihydroxypregn-4-ene-3,20-dione
  • 4-pregnene-11-B-17-A-diol-3-20-dione
  • (8S,9S,10R,13S,14S,17R)-17-acetyl-11,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
  • 11β,17α-Dihydroxy-4-pregnene-3,20-dione, 11β,17α-Dihydroxyprogesterone, 21-Desoxycortisol, 4-Pregnene-11β,17α-diol-3,20-dione
  • 11β,17-Dihydroxypregn-4-ene-3,20-dione
  • C05497
  • (11β)-11,17-Dihydroxypregn-4-ene-3,20-dione
  • 11β,17-Dihydroxypogesterone
  • 21-Dehydrohydrocortisone
  • 21-Deoxyhydrocortisone
  • Pregn-4-ene-11β,17α-diol-3,20-dione
  • 4-Pregnen-11,17a-diol-3,20-dione-d8
  • 11β,17α-Dihydroxy-4-pregnene-3,20-dione
  • 11β,17α-Dihydroxyprogesterone
  • 4-Pregnene-11β,17α-diol-3,20-dione
  • 21-Deoxycortisol solution
  • Hydrocortisone EP Impurity L
  • Hydrocortisone impurity L (EP)
  • Pregn-4-ene-3,20-dione,11,17-dihydroxy-, (11b)-
  • HYDROCORTISONE IMPURITY L (OXENOL)
  • Hydrocortisone Impurity L
  • Hydrocortisone EP IMP L
  • Hydrocortisone Impurity 12（Hydrocortisone EP Impurity L）
  • Desoxycortisol (solution)
  • Desoxycortisol
  • Hydrocortisone EP Impurity L (Oxenol)
  • Hydrocortisone Acetate EP Impurity B
  • Hydrocortisone EP Impurity L (Hydrocortisone Acetate EP Impurity B)
  • Hydrocortisone Acetate EP Impurity B (Hydrocortisone EP Impurity L)
  • (8S,9S,10R,11S,13S,14S,17R)-17-Acetyl-11,17-dihydroxy-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one
  • 11β,17α-Dihydroxypregn-4-ene-3,20-dione
  • Hydrocortisone EP Impurity LQ: What is Hydrocortisone EP Impurity L Q: What is the CAS Number of Hydrocortisone EP Impurity L Q: What is the storage condition of Hydrocortisone EP Impurity L Q: What are the applications of Hydrocortisone EP Impurity L
  • 11beta,17-Dihydroxypregn-4-ene-3,20-dione (Oxenol)
  • Pregn-4-ene-3,20-dione, 11,17-dihydroxy-, (11β)-
  • 4-PREGNEN-11β, 17-DIOL-3, 20-DIONE
  • Azlocillin Impurity 7
  • 21-Deoxycortisol-[13C3] in Methanol
  • 11-Deoxycortisol (2,3,4-13C3,99%)
  • Hydrocortisone EP Impurity L (Hydrocortisone Acetate EP Impurity B, Oxenol)
  • Hydrocortisone Aceate EP Impurity B
  • 641-77-0
  • Steroids
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals