11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE Property

Melting point:

225-228 °C

Boiling point:

523.9±50.0 °C(Predicted)

Density 

1.21±0.1 g/cm3(Predicted)

Flash point:

9℃

storage temp. 

-20°C

solubility 

Chloroform (Slightly), Methanol (Slightly, Heated)

form 

Solid

pka

12.86±0.70(Predicted)

color 

White to Pale Yellow

Safety

Hazard Codes 

F,T

Risk Statements 

11-23/24/25-39/23/24/25

Safety Statements 

7-16-36/37-45

RIDADR 

UN1230 - class 3 - PG 2 - Methanol, solution

WGK Germany 

3

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H370Causes damage to organs

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P311Call a POISON CENTER or doctor/physician.

11BETA,17ALPHA-DIHYDROXY-4-PREGNENE-3,20-DIONE Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

21-Deoxy Cortisol (Hydrocortisone EP Impurity L) is a metabolite of Fluticasone propionate (F599500).

Uses

A metabolite of Fluticasone propionate (F599500).

Definition

ChEBI: 21-deoxycortisol is a deoxycortisol that is 17xi-pregn-4-ene-3,20-dione substituted by a beta-hydroxy group at position 11 and an alpha-hydroxy group at position 17. It is a marker of virilizing adrenal hyperplasia caused by 21-hydroxylase deficiency. It has a role as a human blood serum metabolite and a mouse metabolite. It is an 11beta-hydroxy steroid, a 17alpha-hydroxy-C21-steroid, a tertiary alpha-hydroxy ketone and a deoxycortisol.