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CYCLEANINE

Product Name
CYCLEANINE
CAS No.
518-94-5
Chemical Name
CYCLEANINE
Synonyms
Cycleanin;CYCLEANINE;CYCLEANINE USP/EP/BP;o-Methylnorcycleanine;Methylisochondodendrine;Cycleanine (6ci,7ci,8ci);Dimethylisochondodendrine;o,o-Dimethylisochondodendrin;o,o-Dimethylisochondrodendrine;7,7'-O,O-DiMethylisochondodendrine
CBNumber
CB8241896
Molecular Formula
C38H42N2O6
Formula Weight
622.75
MOL File
518-94-5.mol
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CYCLEANINE Property

Melting point:
272-273 °C
Boiling point:
691.6±55.0 °C(Predicted)
Density 
1.172±0.06 g/cm3(Predicted)
storage temp. 
4°C, away from moisture and light
solubility 
Acetone: soluble; Dichloromethane: soluble; DMSO: soluble; Ethyl Acetate: soluble
form 
A solid
pka
7.56±0.20(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
300133
Product name
Cycleanine
Packaging
20mg
Price
$390
Updated
2021/12/16
TRC
Product number
C990260
Product name
Cycleanine
Packaging
2.5mg
Price
$685
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC159175
Product name
Cycleanine
Packaging
25mg
Price
$350
Updated
2021/12/16
AK Scientific
Product number
8080AH
Product name
Cycleanine
Packaging
5mg
Price
$455
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0002126
Product name
CYCLEANINE
Purity
95.00%
Packaging
5MG
Price
$505.29
Updated
2021/12/16
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CYCLEANINE Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, from the white herbs, geohuai, light leaf geohuai, southern rotundo, Sichuan rotundo, wah's monohuai, tin sheng vine.

Uses

Cycleanine is an alkaloid obtained from the Triclisia subcordata Oliv (Menispermeaceae) which is a medicinal plant used to treat various diseases in West Africa. Displays in-vitro anti-ovarian cancer activity.

Definition

ChEBI: Cycleanine is a member of isoquinolines and a bisbenzylisoquinoline alkaloid.

in vivo

Cycleanine inhibits the KCl-induced contraction of rabbit aortic rings with an IC50 of 0.8 nM[1].

IC 50

L-type calcium channel

CYCLEANINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from CYCLEANINE manufacturers

Career Henan Chemical Co
Product
Cycleanine 518-94-5
Price
US $9.80/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
20 tons
Release date
2020-01-09

518-94-5, CYCLEANINERelated Search:


  • 8,11:20,23-DIETHENO-1H,12H-[1,10]DIOXACYCLOOCTADECINO[2,3,4-IJ:11,12,13-I'J']DIISOQUINOLINE,2,3,12A,13,14,15,24,24A-OCTAHYDRO-5,6,17,18-TETRAMETHOXY-1,13-DIMETHYL-, [12AR-(12AR*,24AR*)]-
  • (1R)-2,2'-Dimethyl-6,6',7,7'-tetramethoxy-7,18:11',18-diseco-8,18:12',18-dicyclotubocuraran
  • 8,11:20,23-Dietheno-1H,12H-(1,10)dioxacyclooctadecino(2,3,4-ij:11,12,13-I'J')diisoquinoline, 2,3,12A,13,14,15,24,24A-octahydro-1,13-dimethyl-5,6,17,18-tetramethoxy-, (12ar-(12ar*,24ar*))-
  • Cycleanine (6ci,7ci,8ci)
  • Dimethylisochondodendrine
  • o,o-Dimethylisochondodendrin
  • CYCLEANINE
  • CYCLEANINE: 8,11:20,23-DIETHENO-1H,12H-[1,10]DIOXACYCLOOCTADECINO[2,3,4-IJ:11,12,13-I'J']DIISOQUINOLINE,2,3,12A,13,14,15,24,24A-OCTAHYDRO-5,6,17,18-TETRAMETHOXY-1,13-DIMETHYL-, [12AR- (12AR*,24AR*)]-,
  • Cycleanin
  • o,o-Dimethylisochondrodendrine
  • o-Methylnorcycleanine
  • 7,7'-O,O-DiMethylisochondodendrine
  • Methylisochondodendrine
  • 8,11:20,23-Dietheno-1H,12H-[1,10]dioxacyclooctadecino[2,3,4-ij:11,12,13-i'j']diisoquinoline, 2,3,12a,13,14,15,24,24a-octahydro-5,6,17,18-tetramethoxy-1,13-dimethyl-, (12aR,24aR)-
  • CYCLEANINE USP/EP/BP
  • (11R,51R)-16,17,56,57-Tetramethoxy-12,52-dimethyl-11,12,13,14,51,52,53,54-octahydro-2,6-dioxa-1(8,1),5(1,8)-diisoquinolina-3,7(1,4)-dibenzenacyclooctaphane
  • 518-94-5