Atractylenolide III

Product Name: Atractylenolide III
CAS No.: 73030-71-4
Chemical Name: Atractylenolide III
Synonyms: ICodonolactone;ATRACTYLENOLIDE;Leucolactone III;Atractylenolide-3;Atracylenolide III;8-HYDROXYASTEROLIDE;ATRACTYLENOLIDE III;Atractylenolide beta;Atractylenolide III, BR;Atractylenolide III USP/EP/BP
CBNumber: CB1678604
Molecular Formula: C15H20O3
Formula Weight: 248.32
MOL File: 73030-71-4.mol

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Atractylenolide III Property

Melting point:: 166-169 °C(Solv: chloroform (67-66-3))
Boiling point:: 424.6±45.0 °C(Predicted)
Density: 1.18±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: methanol: soluble1mg/mL, clear, colorless
pka: 10.73±0.60(Predicted)
form: powder or crystals
color: white to off-white
biological source: Atractylodes macrocephala Koidz.
InChI: InChI=1S/C15H20O3/c1-9-5-4-6-14(3)8-15(17)12(7-11(9)14)10(2)13(16)18-15/h11,17H,1,4-8H2,2-3H3/t11-,14+,15-/m0/s1
InChIKey: FBMORZZOJSDNRQ-GLQYFDAESA-N
SMILES: O1C(=O)C(C)=C2C[C@]3([H])[C@@](C)(C[C@]12O)CCCC3=C

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Safety

WGK Germany: 3
Hazardous Substances Data: 73030-71-4(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A2987
Product name: Atractylenolide III
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $271.6
Updated: 2025/07/31

Sigma-Aldrich

Product number: A2987
Product name: Atractylenolide III
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $1250
Updated: 2025/07/31

TCI Chemical

Product number: A3609
Product name: Atractylenolide III
Packaging: 100MG
Price: $363
Updated: 2025/07/31

Cayman Chemical

Product number: 24911
Product name: Atractylenolide III
Purity: ≥98%
Packaging: 1mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 24911
Product name: Atractylenolide III
Purity: ≥98%
Packaging: 5mg
Price: $220
Updated: 2024/03/01

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Atractylenolide III Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Atractylodes macrocephala Koidz.

Uses

Atractylenolide III enhances energy metabolism by increasing the SIRT-1 and PGC1α expression.

Definition

ChEBI: Atractylenolide III is a naphthofuran. It has a role as a metabolite.

Biological Activity

Atractylenolide III possesses anti-inflammatory and anticancer properties.

in vivo

Atractylenolide III (5 and 10 mg/kg, p.o.) shows gastroprotective effects and reduces 70% ethanol-induced gastric ulcer in rats^[2].
Atractylenolide III (30 mg/kg, oral gavage for 14 days or 28 days) reduces depressive- and anxiogenic-like behaviors in rat depression models in Lipopolysaccharide (LPS) (HY-D1056) and chronic unpredictable mild stress (CUMS) induced rat depression model^[5].

Animal Model:	70% ethanol-induced gastric ulcers in rats^[2]
Dosage:	5 and 10 mg/kg
Administration:	p.o.
Result:	Inhibited gastric ulcer formation and the necrotic erosion of gastric mucosa. Downregulated the MMP-2/9 expression by activating the TIMP-2 and TIMP-1 expressions.

Atractylenolide III Preparation Products And Raw materials

Raw materials

Preparation Products

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Atractylenolide III Suppliers

China 245 Germany 1 Japan 1 United Kingdom 3 United States 19 USA 1 Global 270

Shanghai Moqi Biological Technology Co., LTD

Tel: 021-38218169 13681877033
Email: 2702713455@qq.com
Country: China
ProdList: 9964
Advantage: 58

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Shenzhen Sungening Bio-Tech Co., Ltd

Tel: +86-0755-89668383
Fax: +86-0755-89594066/4038
Email: sales@sungening.com
Country: China
ProdList: 1319
Advantage: 65

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4747
Advantage: 58

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 5653
Advantage: 65

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4999
Advantage: 60

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

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View Lastest Price from Atractylenolide III manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: Atractylenolide III 73030-71-4
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-13

Sichuan Zhuoyu Yantang Technology Co., Ltd.

Product: Atractylenolide III 73030-71-4
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-09-05

Shaanxi Haibo Biotechnology Co., Ltd

Product: Atractylenolide III 73030-71-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 2000ton
Release date: 2023-12-05

73030-71-4, Atractylenolide IIIRelated Search:

Dimethyl sebacate Dimethyl fumarate Dimethyl ether D-(+)-Glucono-1,5-lactone N,N-Dimethylformamide Spironolactone Dimethyl carbonate Dimethyl phthalate ETHANE Dimethyl sulfoxide Atractylenolide-1 2-ATRACTYLENOLIDE ISOAMYL TIGLATE 5-HYDROXY-4-METHYL-2(5H)FURANONE ETHYL TRANS-2-DECENOATE HEXYL TIGLATE BUTYL TIGLATE ATRACTYLENOLIDE Ⅲ

Atractylenolide III (ICodonolactone

ICodonolactone

ATRACTYLENOLIDE III

8-HYDROXYASTEROLIDE

ATRACTYLENOLIDE

Atractylenolide beta

(4aS,8aR,9aS)-9a-Hydroxy-3,8a-dimethyl-5-methylidene-4,4a,6,7,8,9-hexahydrobenzo[f][1]benzoxol-2-one

(4aS)-4a,5,6,7,8,8a,9,9a-Octahydro-9aβ-hydroxy-3,8aβ-dimethyl-5-methylenenaphtho[2,3-b]furan-2(4H)-one

Naphtho[2,3-b]furan-2(4H)-one,4a,5,6,7,8,8a,9,9a-octahydro-9a-hydroxy-3,8a-dimethyl-5-methylene-,(4aS,8aR,9aS)-

Atractylenolide III000000, 98%, from Atractylodes macrocephala Koidz.

Atractylenolide III, BR

Atracylenolide III

Atractylenolide III USP/EP/BP

(4aS,8aR,9aS)-9a-Hydroxy-3,8a-dimethyl-5-methylene-4a,5,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(4H)-one

Atractylenolide-3

Leucolactone III

Atractylenolide III, 10 mM in DMSO

73030-71-4

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

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