ChemicalBook > CAS DataBase List > Esculin
Esculin
Description References- Product Name
- Esculin
- CAS No.
- 531-75-9
- Chemical Name
- Esculin
- Synonyms
- ESCULIN;Escosyl;BICOLOIN;AESCULIN;POLYDROM;Esculine;Bicolorin;Crataegin;Polychrom;vitaminc2
- CBNumber
- CB8245061
- Molecular Formula
- C15H16O9
- Formula Weight
- 340.28
- MOL File
- 531-75-9.mol
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Esculin Property
- Melting point:
- 203 °C
- alpha
- -88 º (c=2,dioxane/water1:1)
- Boiling point:
- 396.1°C (rough estimate)
- Density
- 0.791 g/mL at 20 °C
- vapor pressure
- 0Pa at 25℃
- refractive index
- -79 ° (C=2.4, 50% Dioxane)
- Flash point:
- 15 °C
- storage temp.
- 2-8°C
- solubility
- methanol: 50 mg/mL hot, clear to very faintly turbid, yellow-green fluoresc.
- pka
- 7.00±0.20(Predicted)
- form
- Liquid
- color
- Clear
- optical activity
- [α]20/D 41±2°, c = 5% in pyridine
- Water Solubility
- MODERATELY SOLUBLE
- Merck
- 3698
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- InChIKey
- YRABYCJKUBFWQY-FHXAZYNBSA-N
- LogP
- -1.307 (est)
- CAS DataBase Reference
- 531-75-9(CAS DataBase Reference)
- NIST Chemistry Reference
- 7-Hydroxy-2-oxo-2h-chromen-6-yl hexopyranoside(531-75-9)
- EPA Substance Registry System
- Esculin (531-75-9)
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Safety
- Hazard Codes
- F,C,Xi
- Risk Statements
- 11-20/21/22-34-68/20/21/22-36/37/38
- Safety Statements
- 26-36/37/39-45-24/25-36/37-16
- RIDADR
- UN 2924 3/PG 2
- WGK Germany
- 3
- RTECS
- DJ3085000
- F
- 3-10-23
- HS Code
- 29389090
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- E8250
- Product name
- Esculin hydrate
- Purity
- ≥98%
- Packaging
- 5g
- Price
- $62
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- Y0001612
- Product name
- Esculin
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- 2 ea
- Price
- $156
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 02350
- Product name
- Esculin hydrate
- Purity
- ≥98.0%(HPLC)
- Packaging
- 10g
- Price
- $88.8
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 02350
- Product name
- Esculin hydrate
- Purity
- ≥98.0%(HPLC)
- Packaging
- 50g
- Price
- $320
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 06212
- Product name
- Esculin hydrate
- Purity
- analytical standard
- Packaging
- 100mg
- Price
- $75.4
- Updated
- 2022/05/15
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Esculin Chemical Properties,Usage,Production
Description
Aesculin (also Esculin) is a glucoside compound, which occurs naturally in unprocessed seeds, leaves, bark, and flowers of horse chestnut. Aesculin is used for the identification of bacteria, for the treatment of hemorrhoids and venous peripheral diseases. In cosmetics, aesculin was found to be effective in the treatment of aging skin. Owing to its ultraviolet absorbing activity, aesculin is employed in tanning preparations. Aesculin can be also used as a substrate for the detection of ß-gluocosidase activity in polyacrylamide gels.
References
[1] Anna D. Orla-Jensen, About the application of aesculin for the identification of bacteria, APMIS, 1934, vol. 11, 312-322
[2] S. Srijayanta, A. Raman and B. L. Goodwin, A comparative study of the constituents of Aesculus hippocastanum and Aesculus indica, Journal of Medical Food, 1999, vol. 2, 45-50
[3] Ki-Sun Kwon, Jaehoon Lee, Hyung Gyoo Kang and Yung Chil Hah, Detection of ß-Glucosidase Activity in Polyacrylamide Gels with Esculin as Substrate, Appl. Environ. Microbil., 1994, vol. 80, 4584-4586
[4] Dennis J Mckenna, Kenneth Jones, Kerry Hughes and Virginia M Tyler, Botanical Medicines: The Desk Reference for Major Herbal Supplements, Second Edition, 2011
Chemical Properties
White to nearly white
Uses
esculin is used as a skin protectant in ointments and creams. This is a glucoside compound originally obtained from the leaves and bark of the horse chestnut tree.
Uses
esculoside is utilized in formulations for the treatment of cellulite. es culoside is apparently beneficial for impaired microcirculation.
Uses
Esculin hydrate has been used as a component of sporulation-inducing esculin agar. It has also been used for esculin uptake assay.
Definition
ChEBI: A hydroxycoumarin that is the 6-O-beta-D-glucoside of esculetin.
General Description
Esculin hydrate has vasoprotective and venotonic properties.
Flammability and Explosibility
Not classified
Biochem/physiol Actions
Esculin is a coumarin glycoside that demonstrates antioxidant activitites and protection against chemically-induced carcinogenesis. Esculin is utilized in microbiology for the isolation and identification of Enterococcus (group D streptococci).
Esculin Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Esculin manufacturers
Jinan Ruitong Biotech Co., Ltd.
- Product
- Esculin 531-75-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1
- Release date
- 2025-08-21
Hebei Zhuanglai Chemical Trading Co Ltd
- Product
- Esculin 531-75-9
- Price
- US $55.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2024-11-26
BINBO BIOLOGICAL CO.,LTD
- Product
- Esculin 531-75-9
- Price
- US $5.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000 kg
- Release date
- 2024-12-17
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