Esculin

Description References

Product Name: Esculin
CAS No.: 531-75-9
Chemical Name: Esculin
Synonyms: ESCULIN;Escosyl;BICOLOIN;AESCULIN;POLYDROM;Esculine;Bicolorin;Crataegin;Polychrom;vitaminc2
CBNumber: CB8245061
Molecular Formula: C15H16O9
Formula Weight: 340.28
MOL File: 531-75-9.mol

More

Less

Esculin Property

Melting point:: 203 °C
alpha: -88 º (c=2,dioxane/water1:1)
Boiling point:: 396.1°C (rough estimate)
Density: 0.791 g/mL at 20 °C
vapor pressure: 0Pa at 25℃
refractive index: -79 ° (C=2.4, 50% Dioxane)
Flash point:: 15 °C
storage temp.: 2-8°C
solubility: methanol: 50 mg/mL hot, clear to very faintly turbid, yellow-green fluoresc.
form: Liquid
pka: 7.00±0.20(Predicted)
color: Clear
optical activity: [α]20/D 41±2°, c = 5% in pyridine
Water Solubility: MODERATELY SOLUBLE
Merck: 3698
Stability:: Stable. Incompatible with strong oxidizing agents.
InChIKey: YRABYCJKUBFWQY-FHXAZYNBSA-N
LogP: -1.307 (est)
CAS DataBase Reference: 531-75-9(CAS DataBase Reference)
NIST Chemistry Reference: 7-Hydroxy-2-oxo-2h-chromen-6-yl hexopyranoside(531-75-9)
EPA Substance Registry System: Esculin (531-75-9)

More

Less

Safety

Hazard Codes: F,C,Xi
Risk Statements: 11-20/21/22-34-68/20/21/22-36/37/38
Safety Statements: 26-36/37/39-45-24/25-36/37-16
RIDADR: UN 2924 3/PG 2
WGK Germany: 3
RTECS: DJ3085000
F: 3-10-23
HS Code: 29389090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E8250
Product name: Esculin hydrate
Purity: ≥98%
Packaging: 5g
Price: $58.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: 02350
Product name: Esculin hydrate
Purity: ≥98.0%(HPLC)
Packaging: 10g
Price: $83.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: 02350
Product name: Esculin hydrate
Purity: ≥98.0%(HPLC)
Packaging: 50g
Price: $302
Updated: 2024/03/01

Sigma-Aldrich

Product number: 06212
Product name: Esculin hydrate
Purity: analytical standard
Packaging: 100mg
Price: $75.4
Updated: 2022/05/15

Sigma-Aldrich

Product number: Y0001612
Product name: Esculin
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: y0001612
Price: $153
Updated: 2024/03/01

More

Less

Esculin Chemical Properties,Usage,Production

Description

Aesculin (also Esculin) is a glucoside compound, which occurs naturally in unprocessed seeds, leaves, bark, and flowers of horse chestnut. Aesculin is used for the identification of bacteria, for the treatment of hemorrhoids and venous peripheral diseases. In cosmetics, aesculin was found to be effective in the treatment of aging skin. Owing to its ultraviolet absorbing activity, aesculin is employed in tanning preparations. Aesculin can be also used as a substrate for the detection of ß-gluocosidase activity in polyacrylamide gels.

References

[1] Anna D. Orla-Jensen, About the application of aesculin for the identification of bacteria, APMIS, 1934, vol. 11, 312-322
[2] S. Srijayanta, A. Raman and B. L. Goodwin, A comparative study of the constituents of Aesculus hippocastanum and Aesculus indica, Journal of Medical Food, 1999, vol. 2, 45-50
[3] Ki-Sun Kwon, Jaehoon Lee, Hyung Gyoo Kang and Yung Chil Hah, Detection of ß-Glucosidase Activity in Polyacrylamide Gels with Esculin as Substrate, Appl. Environ. Microbil., 1994, vol. 80, 4584-4586
[4] Dennis J Mckenna, Kenneth Jones, Kerry Hughes and Virginia M Tyler, Botanical Medicines: The Desk Reference for Major Herbal Supplements, Second Edition, 2011

Chemical Properties

White to nearly white

Uses

esculin is used as a skin protectant in ointments and creams. This is a glucoside compound originally obtained from the leaves and bark of the horse chestnut tree.

Uses

esculoside is utilized in formulations for the treatment of cellulite. es culoside is apparently beneficial for impaired microcirculation.

Uses

Esculin hydrate has been used as a component of sporulation-inducing esculin agar. It has also been used for esculin uptake assay.

Definition

ChEBI: A hydroxycoumarin that is the 6-O-beta-D-glucoside of esculetin.

General Description

Esculin hydrate has vasoprotective and venotonic properties.

Flammability and Explosibility

Not classified

Biochem/physiol Actions

Esculin is a coumarin glycoside that demonstrates antioxidant activitites and protection against chemically-induced carcinogenesis. Esculin is utilized in microbiology for the isolation and identification of Enterococcus (group D streptococci).

Esculin Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Esculin Suppliers

Belgium 1 Canada 1 China 341 Europe 3 France 1 Germany 3 India 15 Switzerland 2 United Kingdom 12 United States 46 Global 425

Carbosynth

Tel: --
Fax: --
Email: sales@carbosynth.com
Country: United Kingdom
ProdList: 6005
Advantage: 58

Avonchem/Chromos Express Ltd.

Tel: --
Fax: --
Email: info@avonchem.co.uk
Country: United Kingdom
ProdList: 1189
Advantage: 50

Apollo Scientific Ltd.

Tel: --
Fax: --
Email: sales@apolloscientific.co.uk
Country: United Kingdom
ProdList: 6084
Advantage: 88

Melford Laboratories Ltd.

Tel: --
Fax: --
Email: sales@melford.co.uk
Country: United Kingdom
ProdList: 1516
Advantage: 64

Carbosynth Limited

Tel: --
Fax: --
Email: sales@carbosynth.com
Country: United Kingdom
ProdList: 6581
Advantage: 61

Leancare Ltd.

Tel: --
Fax: --
Email: enquiry@leancare.co.uk
Country: United Kingdom
ProdList: 6446
Advantage: 42

MOLEKULA Ltd.

Tel: --
Fax: --
Email: kevinbanks@molekula.com
Country: United Kingdom
ProdList: 6140
Advantage: 66

CARBONE SCIENTIFIC CO.,LTD

Tel: --
Fax: --
Email: sales@carbonesci.com
Country: United Kingdom
ProdList: 6666
Advantage: 30

Eurolabs Limited

Tel: --
Fax: --
Country: United Kingdom
ProdList: 6309
Advantage: 46

ETA SCIENTIFIC Co.,Ltd

Tel: --
Fax: --
Email: sales@etascientific.com
Country: United Kingdom
ProdList: 6090
Advantage: 34

UK GREEN SCIENTIFIC CO.,LIMITED

Tel: --
Fax: --
Email: sales@gs-chem.com
Country: United Kingdom
ProdList: 6098
Advantage: 47

Sequoia Research Products Ltd.

Tel: --
Fax: --
Email: sales@seqchem.com
Country: United Kingdom
ProdList: 3113
Advantage: 69

More

Less

View Lastest Price from Esculin manufacturers

Hebei Chuanghai Biotechnology Co,.LTD

Product: Esculin 531-75-9
Price: US $9.00/KG
Min. Order: 1KG
Purity: 99.9
Supply Ability: 1 ton
Release date: 2024-08-15

R&D Scientific Inc.

Product: Esculin 531-75-9
Price: US $780.00/Kg
Min. Order: 1Kg
Purity: 98
Supply Ability: 500 Kg
Release date: 2024-06-24

Hebei Kingfiner Technology Development Co.Ltd

Product: ESCULIN 531-75-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500000%
Release date: 2023-11-27

531-75-9, EsculinRelated Search:

Isofraxidin Tetrahydro-4H-pyran-4-one Centchroman Tetrahydrofuran FRAXIN Furazolidone CHLOROPHOSPHONAZO III Esculin aglucon,Esculin aglycon D-(-)-Salicin Icariin Matrine ERIOCITRIN AESCIN IB(SH) Eribulin Erlotinib hydrochloride Eribulin Mesylate ERIODICTYOL-7-GLUCOSIDE 4-Ethoxyphenol

BICOLOIN

ESCULETIN-6-O-GLUCOSIDE

ESCULIN

ESCULETIN-6-GLUCOSIDE

ESCULOSIDE

Esculinsesquimonohydrate

2H-1-Benzopyran-2-one, 6-(beta-D-glucopyranosyloxy)-7-hydroxy-

6,7-DIHYDROXYCOUMARIN-6-O-GLUCOSIDE

6-(beta-d-glucopyranosyloxy)-7-hydroxy-2h-1-benzopyran-2-one

6-(BETA-D-GLUCOPYRANOSYLOXY)-7-HYDROXY-2H-1-BEZOPYRAN-2-ONE

6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one

6,7-Dihydrocoumarin-6-glucoside

6-β-Glucosido-7-hydrox

Aesculin;Bicolorin;6,7-Dihydrocoumarin-6-glucoside;6,7-Dihydroxycoumarin 6-glucoside;Enallachrome;Escosyl;Esculetin-6-β-D-glucopyranoside;Esculin;Esculinic acid;Esculoside;6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one;6-β-Glucosido-7-hydrox

Esculinic acid

ESCULIN, PLANT EXTRACT 10:1

AESCULIN (Esculin Sesquihydrate)

EsculinNLT98%

7-hydroxycoumarin-6-yl beta-d-glucopyranoside

ESCULIN(ESCULETIN-6-GLUCOSIDE)(P)

7-HYDROXY-6-O-GLUCOSYLCOUMARIN

6-(β-D-Glucopyranosyloxy)-7-hydroxycoumarin

ESCULIN extrapure

7-hydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-1-benzopyran-2-one hydrate

AESCULETIN

AESCULETIN-6B-D-GLUCOPYRANOSIDE

AESCULETIN-6-BETA-D-GLUCOPYRANOSIDE

AESCULIN

POLYDROM

POLYCHROME

6-(beta-d-glucopyranosyloxy)-7-hydroxy-2h-1-benzopyran-2-on

Bicolorin

Crataegin

Enallachrome

Escosyl

Esculetin 6-beta-D-glucoside

Esculine

Polychrom

Vitamin C2

vitaminc2

6,7-DIHYDROXYCOUMARIN 6-GLUCOSIDE

Esculin，Esculine

6-(b-D-Glucopyranosyloxy)-7-hydroxycoumarin

Esculetin 6-b-D-glucoside

Esculin hydrate,97%

6-glucoside hydrate

F. bangeana DC.p.e

6-glucoside hydrat

7-hydroxy-6-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyMethyl)tetrahydro-2H-pyran-2-yl)oxy)-2H-chroMen-2-one

Esculin hydrate, 97% 10GR

Aesculin (Esculin)

Schillerstoff

2H-1-Benzopyran-2-one,6-(b-D-glucopyranosyloxy)-7-hydroxy-

2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy)-7-hydroxy-

6,7-dihydroxychromen-2-one 6-β-D-glucoside

6,7-dihydroxycoumarin 6-β-D-glucoside

7-hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy- 6-(hydroxymethyl)-2-tetrahydropyranyl]oxy}-2-chromenone

Esculetin 6-β-D-glucoside