ChemicalBook > CAS DataBase List > 2,3-dimethyl-6-nitro-2H-indazole

2,3-dimethyl-6-nitro-2H-indazole

Product Name
2,3-dimethyl-6-nitro-2H-indazole
CAS No.
444731-73-1
Chemical Name
2,3-dimethyl-6-nitro-2H-indazole
Synonyms
Pazopanib Impurity 19;3-Methly-6-nitroindazole;2,3-dimethyl-6-nitrobazole;2,3-Dimethyl-6-nitro-1H-i...;2,3-dimethyl-6-nitro-indazole;3-diMethyl-6-nitro-2H-indazole;2,3-dimethyl-6-nitro-1H-indazole;2,3-DIMETHYL-6-NITRO-2H-INDAZOLE;2H-Indazole, 2,3-diMethyl-6-nitro-;2,3-DIMETHYL-6-NITRO-2H-INDAZOLE ISO 9001：2015 REACH
CBNumber
CB82455022
Molecular Formula
C9H9N3O2
Formula Weight
191.19
MOL File
444731-73-1.mol
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2,3-dimethyl-6-nitro-2H-indazole Property

Melting point:
183-186°C
Boiling point:
377.0±22.0 °C(Predicted)
Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
-0.55±0.30(Predicted)
form 
Solid
color 
Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
159866
Product name
2,3-Dimethyl-6-nitro-2H-indazole
Packaging
500mg
Price
$425
Updated
2021/12/16
TRC
Product number
D471055
Product name
2,3-Dimethyl-6-nitro-2H-indazole
Packaging
500mg
Price
$130
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM1052130
Product name
2,3-DIMETHYL-6-NITRO-2H-INDAZOLE
Purity
95.00%
Packaging
1G
Price
$130.2
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD148529
Product name
2,3-Dimethyl-6-nitro-2H-indazole
Packaging
500mg
Price
$570
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
69723
Product name
2,3-Dimethyl-6-nitro-2H-indazole
Packaging
500mg
Price
$625
Updated
2021/12/16
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2,3-dimethyl-6-nitro-2H-indazole Chemical Properties,Usage,Production

Uses

2,3-Dimethyl-6-nitro-2H-indazole is an impurity in the synthesis of Pazopanib (P210925) hydrochloride, an oral angiogenesis inhibitor targeting VEGFR and PDGFR.

structure and hydrogen bonding

In the mol-ecule of 2,3-dimethyl-6-nitro-2H-indazole, C9H9N3O2, the indazole ring system is almost planar [maximum deviation = 0.019 (3) Å for the C atom bearing the nitro group]. In the crystal structure, inter-molecular C—H...O inter-actions link the mol-ecules into centrosymmetric dimers, forming R 2 2(18) ring motifs. Aromatic π–π contacts between indazole rings [centroid–centroid distances = 3.632 (1) and 3.705 (1)?] may further stabilize the structure[1].

References

[1] Yan Chen, Ping Wei, Zheng Fang. “2,3-Dimethyl-6-nitro-2H-indazole.” Acta crystallographica. Section E, Structure reports online 65 Pt 8 (2009): o1775.

2,3-dimethyl-6-nitro-2H-indazole Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,3-dimethyl-6-nitro-2H-indazole manufacturers

Henan Fengda Chemical Co., Ltd
Product
2,3-DIMETHYL-6-NITRO-2H-INDAZOLE 444731-73-1
Price
US $6.00-0.20/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-28
Guangzhou Sunton Biotechnology Co., Ltd.
Product
2, 3-dimethyl-6-nitroindazole 444731-73-1
Price
US $48.00-40.00/KG
Min. Order
1KG
Purity
99.99%
Supply Ability
20 tons
Release date
2021-06-09
Shaanxi Dideu Medichem Co. Ltd
Product
2,3-dimethyl-6-nitro-2H-indazole 444731-73-1
Price
US $0.00-0.00/KG
Min. Order
5g
Purity
99%+
Supply Ability
100 tons
Release date
2019-12-25

444731-73-1, 2,3-dimethyl-6-nitro-2H-indazole Related Search:

3-Methyl-6-nitroindazole 1,3-DiMethyl-6-aMino-1H-indazole 3-Methyl-6-nitro-2H-indazole Pazopanib Related Compound 3 1,3-Dimethyl-6-nitro-1H-indazole Pazopanib Related Compound 2 2(1H)-Pyrimidinone, 4-chloro- (6CI,9CI) N-(2-chloropyriMidin-4-yl)-N,2,3-triMethyl-2H-indazol-6-aMine Pazopanib 2,3-dimethyl-2H-indazol-6-amine hydrochloride Pazopanib Hydrochloride 2-Ethyl-5-nitrobenzenamine ,98% N-(2-Chloropyrimidin-4-YL)-2,3-dimethyl-2H-indazol-6-amine Pazopanib Impurity 9 Pazopanib Impurity 10 Pazopanib Impurity 2 2-Methyl-5-nitrobenzenesulfonamide 3-AMINO-4-METHYLBENZENESULFONAMIDE

  • 2,3-DIMETHYL-6-NITRO-2H-INDAZOLE
  • 2,3-dimethyl-6-nitro-1H-indazole
  • 2,3-Dimethyl-6-nitro-1H-i...
  • 2H-Indazole, 2,3-diMethyl-6-nitro-
  • 3-Methly-6-nitroindazole
  • 3-diMethyl-6-nitro-2H-indazole
  • Pazopanib Impurity 19
  • 2,3-dimethyl-6-nitro-indazole
  • 2,3-dimethyl-6-nitrobazole
  • 2,3-DIMETHYL-6-NITRO-2H-INDAZOLE ISO 9001：2015 REACH
  • 444731-73-1