2,3-dimethyl-6-nitro-2H-indazole
- Product Name
- 2,3-dimethyl-6-nitro-2H-indazole
- CAS No.
- 444731-73-1
- Chemical Name
- 2,3-dimethyl-6-nitro-2H-indazole
- Synonyms
- Pazopanib Impurity 19;3-Methly-6-nitroindazole;2,3-dimethyl-6-nitrobazole;2,3-Dimethyl-6-nitro-1H-i...;2,3-dimethyl-6-nitro-indazole;3-diMethyl-6-nitro-2H-indazole;2,3-dimethyl-6-nitro-1H-indazole;2,3-DIMETHYL-6-NITRO-2H-INDAZOLE;2H-Indazole, 2,3-diMethyl-6-nitro-;2,3-DIMETHYL-6-NITRO-2H-INDAZOLE ISO 9001:2015 REACH
- CBNumber
- CB82455022
- Molecular Formula
- C9H9N3O2
- Formula Weight
- 191.19
- MOL File
- 444731-73-1.mol
2,3-dimethyl-6-nitro-2H-indazole Property
- Melting point:
- 183-186°C
- Boiling point:
- 377.0±22.0 °C(Predicted)
- Density
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- -0.55±0.30(Predicted)
- form
- Solid
- color
- Yellow
N-Bromosuccinimide Price
- Product number
- 159866
- Product name
- 2,3-Dimethyl-6-nitro-2H-indazole
- Packaging
- 500mg
- Price
- $425
- Updated
- 2021/12/16
- Product number
- D471055
- Product name
- 2,3-Dimethyl-6-nitro-2H-indazole
- Packaging
- 500mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- CHM1052130
- Product name
- 2,3-DIMETHYL-6-NITRO-2H-INDAZOLE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $130.2
- Updated
- 2021/12/16
- Product number
- FD148529
- Product name
- 2,3-Dimethyl-6-nitro-2H-indazole
- Packaging
- 500mg
- Price
- $570
- Updated
- 2021/12/16
- Product number
- 69723
- Product name
- 2,3-Dimethyl-6-nitro-2H-indazole
- Packaging
- 500mg
- Price
- $625
- Updated
- 2021/12/16
2,3-dimethyl-6-nitro-2H-indazole Chemical Properties,Usage,Production
Uses
2,3-Dimethyl-6-nitro-2H-indazole is an impurity in the synthesis of Pazopanib (P210925) hydrochloride, an oral angiogenesis inhibitor targeting VEGFR and PDGFR.
structure and hydrogen bonding
In the mol-ecule of 2,3-dimethyl-6-nitro-2H-indazole, C9H9N3O2, the indazole ring system is almost planar [maximum deviation = 0.019 (3) Å for the C atom bearing the nitro group]. In the crystal structure, inter-molecular C—H...O inter-actions link the mol-ecules into centrosymmetric dimers, forming R 2 2(18) ring motifs. Aromatic π–π contacts between indazole rings [centroid–centroid distances = 3.632 (1) and 3.705 (1)?] may further stabilize the structure[1].
References
[1] Yan Chen, Ping Wei, Zheng Fang. “2,3-Dimethyl-6-nitro-2H-indazole.” Acta crystallographica. Section E, Structure reports online 65 Pt 8 (2009): o1775.
2,3-dimethyl-6-nitro-2H-indazole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,3-dimethyl-6-nitro-2H-indazole manufacturers
- Product
- 2,3-DIMETHYL-6-NITRO-2H-INDAZOLE 444731-73-1
- Price
- US $6.00-0.20/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-03-28
- Product
- 2, 3-dimethyl-6-nitroindazole 444731-73-1
- Price
- US $48.00-40.00/KG
- Min. Order
- 1KG
- Purity
- 99.99%
- Supply Ability
- 20 tons
- Release date
- 2021-06-09
- Product
- 2,3-dimethyl-6-nitro-2H-indazole 444731-73-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 5g
- Purity
- 99%+
- Supply Ability
- 100 tons
- Release date
- 2019-12-25