ChemicalBook > CAS DataBase List > 4-Amino-3-iodobenzotrifluoride

4-Amino-3-iodobenzotrifluoride

Product Name
4-Amino-3-iodobenzotrifluoride
CAS No.
163444-17-5
Chemical Name
4-Amino-3-iodobenzotrifluoride
Synonyms
2-IODO-4-(TRIFLUOROMETHYL)ANILINE;4-AMINO-3-IODOBENZOTRIFLUORIDE;3-iodo-4-aminobenzotrifluoride;4-Amino-3-iodobenzotrifluoride,98%;2-Iodo-4-(trifluoromethyl)aniline>2-iodo-4-(trifluoroMethyl)benzenaMine;4-(TRIFLUOROMETHYL)-2-IODOBENZENAMINE;4-amino-3-iodo-trifluoromethylbenzene;BenzenaMine, 2-iodo-4-(trifluoroMethyl)-;2-Iodo-4-(trifluoromethyl)aniline【4-Amino-3-iodobenzotrifluoride】
CBNumber
CB8245975
Molecular Formula
C7H5F3IN
Formula Weight
287.02
MOL File
163444-17-5.mol
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4-Amino-3-iodobenzotrifluoride Property

Melting point:
50 °C
Boiling point:
252.8±40.0 °C(Predicted)
Density 
1.948±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
powder to crystal
pka
0.70±0.10(Predicted)
color 
Light yellow to Brown
InChI
InChI=1S/C7H5F3IN/c8-7(9,10)4-1-2-6(12)5(11)3-4/h1-3H,12H2
InChIKey
UKKWTZPXYIYONW-UHFFFAOYSA-N
SMILES
C1(N)=CC=C(C(F)(F)F)C=C1I
CAS DataBase Reference
163444-17-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-36/37/39-36/37
RIDADR 
UN2811
HazardClass 
IRRITANT
HS Code 
29214200
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
I0794
Product name
2-Iodo-4-(trifluoromethyl)aniline
Purity
>98.0%(GC)
Packaging
5g
Price
$59
Updated
2025/07/31
TCI Chemical
Product number
I0794
Product name
2-Iodo-4-(trifluoromethyl)aniline
Purity
>98.0%(GC)
Packaging
25g
Price
$229
Updated
2025/07/31
TRC
Product number
I724783
Product name
2-Iodo-4-(trifluoromethyl)aniline
Packaging
250mg
Price
$55
Updated
2021/12/16
SynQuest Laboratories
Product number
3830-K-43
Product name
4-Amino-3-iodobenzotrifluoride
Purity
97%
Packaging
500g
Price
$500
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0022814
Product name
4-AMINO-3-IODOBENZOTRIFLUORIDE
Purity
95.00%
Packaging
5G
Price
$795.8
Updated
2021/12/16
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4-Amino-3-iodobenzotrifluoride Chemical Properties,Usage,Production

Chemical Properties

light brown powder

Synthesis

455-14-1

163444-17-5

Step 2: Synthesis of 2-iodo-4-(trifluoromethyl)aniline In a 500 mL three-necked round-bottomed flask, 4-(trifluoromethyl)aniline (22.5 g, 0.14 mol) and methanol (100 mL) were added. The reaction system was cooled to 0 °C, followed by slow dropwise addition of a dichloromethane (100 mL) solution of ICl (25 g, 0.15 mol). After the dropwise addition, the reaction mixture was stirred at room temperature for 1 hour. The reaction process was monitored by thin layer chromatography (TLC) (unfolding agent: ethyl acetate/petroleum ether = 1:10, Rf = 0.5). Post-treatment: The reaction mixture was concentrated under reduced pressure to remove the solvent. The residue was redissolved in dichloromethane, subsequently washed with water and dried over anhydrous sodium sulfate. Finally, the dried organic phase was concentrated under reduced pressure to give 37.8 g (97% yield) of the target product 2-iodo-4-(trifluoromethyl)aniline. Product characterization: 1H NMR (300 MHz, CDCl3) δ: 7.86 (d, J = 1.2 Hz, 1H), 7.36 (dd, J = 8.4, 1.8 Hz, 1H), 6.73 (d, J = 8.7 Hz, 1H), 4.41 (br, 2H).

References

[1] Heterocycles, 2002, vol. 57, # 3, p. 465 - 476
[2] Patent: US2010/120741, 2010, A1. Location in patent: Page/Page column 91
[3] Patent: WO2011/112731, 2011, A2. Location in patent: Page/Page column 196
[4] Synthesis, 2004, # 11, p. 1869 - 1873
[5] Synlett, 2014, vol. 25, # 3, p. 399 - 402

4-Amino-3-iodobenzotrifluoride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-Amino-3-iodobenzotrifluoride manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
4-Amino-3-iodobenzotrifluoride 163444-17-5
Price
US $0.00-0.00/KG
Min. Order
50mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-08
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Amino-3-iodobenzotrifluoride 163444-17-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
4-Amino-3-iodobenzotrifluoride 163444-17-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

163444-17-5, 4-Amino-3-iodobenzotrifluorideRelated Search:

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  • BenzenaMine, 2-iodo-4-(trifluoroMethyl)-
  • 4-amino-3-iodo-trifluoromethylbenzene
  • 4-(TRIFLUOROMETHYL)-2-IODOBENZENAMINE
  • 4-AMINO-3-IODOBENZOTRIFLUORIDE
  • 2-IODO-4-(TRIFLUOROMETHYL)ANILINE
  • 3-iodo-4-aminobenzotrifluoride
  • 2-iodo-4-(trifluoroMethyl)benzenaMine
  • 4-AMino-3-iodobenzotrifluoride[2-Iodo-4-(trifluoroMethyl)aniline]
  • 2-Iodo-4-(trifluoromethyl)aniline&gt
  • 4-Amino-3-iodobenzotrifluoride,98%
  • 2-Iodo-4-(trifluoromethyl)aniline【4-Amino-3-iodobenzotrifluoride】
  • 163444-17-5
  • C7H5F3IN
  • Fluorine series
  • Aromatic Halides (substituted)
  • API intermediates