4-Amino-3-iodobenzotrifluoride
- Product Name
- 4-Amino-3-iodobenzotrifluoride
- CAS No.
- 163444-17-5
- Chemical Name
- 4-Amino-3-iodobenzotrifluoride
- Synonyms
- 2-IODO-4-(TRIFLUOROMETHYL)ANILINE;4-AMINO-3-IODOBENZOTRIFLUORIDE;3-iodo-4-aminobenzotrifluoride;4-Amino-3-iodobenzotrifluoride,98%;2-Iodo-4-(trifluoromethyl)aniline>2-iodo-4-(trifluoroMethyl)benzenaMine;4-(TRIFLUOROMETHYL)-2-IODOBENZENAMINE;4-amino-3-iodo-trifluoromethylbenzene;BenzenaMine, 2-iodo-4-(trifluoroMethyl)-;2-Iodo-4-(trifluoromethyl)aniline【4-Amino-3-iodobenzotrifluoride】
- CBNumber
- CB8245975
- Molecular Formula
- C7H5F3IN
- Formula Weight
- 287.02
- MOL File
- 163444-17-5.mol
4-Amino-3-iodobenzotrifluoride Property
- Melting point:
- 50 °C
- Boiling point:
- 252.8±40.0 °C(Predicted)
- Density
- 1.948±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 0.70±0.10(Predicted)
- color
- Light yellow to Brown
- InChI
- InChI=1S/C7H5F3IN/c8-7(9,10)4-1-2-6(12)5(11)3-4/h1-3H,12H2
- InChIKey
- UKKWTZPXYIYONW-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=C(C(F)(F)F)C=C1I
- CAS DataBase Reference
- 163444-17-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 20/21/22-36/37/38
- Safety Statements
- 26-36/37/39-36/37
- RIDADR
- UN2811
- HazardClass
- IRRITANT
- HS Code
- 29214200
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H301Toxic if swalloed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- I0794
- Product name
- 2-Iodo-4-(trifluoromethyl)aniline
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $59
- Updated
- 2025/07/31
- Product number
- I0794
- Product name
- 2-Iodo-4-(trifluoromethyl)aniline
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $229
- Updated
- 2025/07/31
- Product number
- I724783
- Product name
- 2-Iodo-4-(trifluoromethyl)aniline
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 3830-K-43
- Product name
- 4-Amino-3-iodobenzotrifluoride
- Purity
- 97%
- Packaging
- 500g
- Price
- $500
- Updated
- 2021/12/16
- Product number
- HCH0022814
- Product name
- 4-AMINO-3-IODOBENZOTRIFLUORIDE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $795.8
- Updated
- 2021/12/16
4-Amino-3-iodobenzotrifluoride Chemical Properties,Usage,Production
Chemical Properties
light brown powder
Synthesis
455-14-1
163444-17-5
Step 2: Synthesis of 2-iodo-4-(trifluoromethyl)aniline In a 500 mL three-necked round-bottomed flask, 4-(trifluoromethyl)aniline (22.5 g, 0.14 mol) and methanol (100 mL) were added. The reaction system was cooled to 0 °C, followed by slow dropwise addition of a dichloromethane (100 mL) solution of ICl (25 g, 0.15 mol). After the dropwise addition, the reaction mixture was stirred at room temperature for 1 hour. The reaction process was monitored by thin layer chromatography (TLC) (unfolding agent: ethyl acetate/petroleum ether = 1:10, Rf = 0.5). Post-treatment: The reaction mixture was concentrated under reduced pressure to remove the solvent. The residue was redissolved in dichloromethane, subsequently washed with water and dried over anhydrous sodium sulfate. Finally, the dried organic phase was concentrated under reduced pressure to give 37.8 g (97% yield) of the target product 2-iodo-4-(trifluoromethyl)aniline. Product characterization: 1H NMR (300 MHz, CDCl3) δ: 7.86 (d, J = 1.2 Hz, 1H), 7.36 (dd, J = 8.4, 1.8 Hz, 1H), 6.73 (d, J = 8.7 Hz, 1H), 4.41 (br, 2H).
References
[1] Heterocycles, 2002, vol. 57, # 3, p. 465 - 476
[2] Patent: US2010/120741, 2010, A1. Location in patent: Page/Page column 91
[3] Patent: WO2011/112731, 2011, A2. Location in patent: Page/Page column 196
[4] Synthesis, 2004, # 11, p. 1869 - 1873
[5] Synlett, 2014, vol. 25, # 3, p. 399 - 402
4-Amino-3-iodobenzotrifluoride Preparation Products And Raw materials
Raw materials
Preparation Products
4-Amino-3-iodobenzotrifluoride Suppliers
- Tel
- --
- Fax
- --
- sales@riccichimica.com
- Country
- Italy
- ProdList
- 2146
- Advantage
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View Lastest Price from 4-Amino-3-iodobenzotrifluoride manufacturers
- Product
- 4-Amino-3-iodobenzotrifluoride 163444-17-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 50mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-08
- Product
- 4-Amino-3-iodobenzotrifluoride 163444-17-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 4-Amino-3-iodobenzotrifluoride 163444-17-5
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09