ChemicalBook > CAS DataBase List > 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one

Product Name
2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
CAS No.
277299-70-4
Chemical Name
2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
Synonyms
2-(3,4-dimethylphenyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one;EltroMbopag II;ELTROMBOPAG INT;Eltrombopag Impurity 35;Eltrombopag Intermediate 1;Eltrombopag olamine Intermediate 4;1-(3,4-Dimethylphenyl)-3-methyl-5-pyrazolone;1-(3,4-diMethylphenyl)-3-Methyl-1H-pyrazol-5-ol;2-(3,4-dimethylphenyl)-5-methyl-1H-pyrazol-3-one;2-Oxo-2,4,5,6,7,7a-Hexahydrothieno [3,2-c] Pyridine
CBNumber
CB82490074
Molecular Formula
C12H14N2O
Formula Weight
202.25
MOL File
277299-70-4.mol
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2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one Property

Melting point:
121.0 to 125.0 °C
Boiling point:
338.5±52.0 °C(Predicted)
Density 
1.121
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
0.79±0.40(Predicted)
color 
Pale Beige to Light Beige
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Safety

HS Code 
2933.19.9000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
D5064
Product name
1-(3,4-Dimethylphenyl)-3-methyl-5-pyrazolone
Purity
>97.0%(GC)(T)
Packaging
1g
Price
$44
Updated
2024/03/01
TCI Chemical
Product number
D5064
Product name
1-(3,4-Dimethylphenyl)-3-methyl-5-pyrazolone
Purity
>97.0%(GC)(T)
Packaging
5g
Price
$222
Updated
2024/03/01
TRC
Product number
D476930
Product name
2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
Packaging
10g
Price
$580
Updated
2021/12/16
AK Scientific
Product number
J96725
Product name
2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
Packaging
1g
Price
$34
Updated
2021/12/16
Chem-Impex
Product number
43262
Product name
1-(3,4-Dimethylphenyl)-3-methyl-5-pyrazolone,≥97%(GC)
Purity
≥97%(GC)
Packaging
1G
Price
$35.88
Updated
2021/12/16
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2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one Chemical Properties,Usage,Production

Uses

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one, is an impurity of Eltrombopag (E508000), which is agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia.

2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one Suppliers

Americas 1 China 185 Europe 1 India 27 Japan 1 United States 8 Global 223
Aladdin Scientific
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View Lastest Price from 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one manufacturers

Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one 277299-70-4
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20tons
Release date
2024-03-29
Hangzhou ICH Biofarm Co., Ltd
Product
2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one 277299-70-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500KG
Release date
2023-07-06
Henan Aochuang Chemical Co.,Ltd.
Product
2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one 277299-70-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-30

277299-70-4, 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-oneRelated Search:

Eltrombopag

  • 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
  • Eltrombopag Impurity 35
  • 2-(3,4-Dimethylphenyl)-5-methyl-1H-pyrazol-3(2H)-one
  • 2-(3,4-dimethylphenyl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one
  • Eltrombopag Intermediate 1
  • EltroMbopag II
  • 2-Oxo-2,4,5,6,7,7a-Hexahydrothieno [3,2-c] Pyridine
  • 1-(3,4-diMethylphenyl)-3-Methyl-1H-pyrazol-5-ol
  • 1H-pyrazol-3(2H)-one,2-(3,4-Dimethylphenyl)-5-methyl-
  • 2-(3,4-Dimethyl-phenyl)-5-methyl-1,2-dihydro-pyrazol-3-one
  • 1-(3,4-Dimethylphenyl)-3-methyl-5-pyrazolone
  • 2-(3,4-dimethylphenyl)-5-methyl-1H-pyrazol-3-one
  • Eltrombopag olamine Intermediate 4
  • 3H-Pyrazol-3-one, 2-(3,4-dimethylphenyl)-1,2-dihydro-5-methyl-
  • 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one ISO 9001：2015 REACH
  • ELTROMBOPAG INT
  • TIANFU CHEM 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
  • 2-(3,4-Dimethylphenyl)-1,2-dihydro-5-methyl-1H-pyrazol-3-one
  • 2-(3,4-dimethylphenyl)-5-methyl-1,2- dihydroxypyrazol-3-one
  • 2-(3,4-Dimethyl phenpyl)-1,2-dihydro-5-methyl-3H-pyrazol-3-one
  • 277299-70-4
  • 77299-70-4