KN-92 (hydrochloride)
- Product Name
- KN-92 (hydrochloride)
- CAS No.
- 1431698-47-3
- Chemical Name
- KN-92 (hydrochloride)
- Synonyms
- CS-1448;KN92-HCl;KN-92 (hydrochloride);KN 92 HYDROCHLORIDE; KN92 HYDROCHLORIDE;N-(2-(((3-(4-Chlorophenyl)allyl)(methyl)amino)methyl)phenyl)-4-methoxybenzenesulfonamide hydrochloride;Inhibitor,derivative,experimental,inactive,KN-92,KN92 hydrochloride,KN92,inhibit,analog,KN 92 hydrochloride,control,KN 92
- CBNumber
- CB82591540
- Molecular Formula
- C24H26Cl2N2O3S
- Formula Weight
- 493.44584
- MOL File
- 1431698-47-3.mol
KN-92 (hydrochloride) Property
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- ≥24.65 mg/mL in DMSO; insoluble in H2O; ≥11.73 mg/mL in EtOH with gentle warming and ultrasonic
- form
- solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 9000890
- Product name
- KN-92 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $107
- Updated
- 2024/03/01
- Product number
- 9000890
- Product name
- KN-92 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $471
- Updated
- 2024/03/01
- Product number
- 9000890
- Product name
- KN-92 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $836
- Updated
- 2024/03/01
- Product number
- orb181267
- Product name
- KN-92-hydrochloride
- Purity
- >98%
- Packaging
- 100mg
- Price
- $986
- Updated
- 2021/12/16
- Product number
- orb181267
- Product name
- KN-92-hydrochloride
- Purity
- >98%
- Packaging
- 250mg
- Price
- $1802
- Updated
- 2021/12/16
KN-92 (hydrochloride) Chemical Properties,Usage,Production
Biological Activity
kn-92 is an inactive analog of kn-93. kn-93 is the cam kinase ii inhibitor. [1]hearts were treated with the cam kinase inhibitor kn-93 or the inactive analog kn-92 (0.5 μm) for 10 min before clofilium exposure. early afterdepolarizations (eads) were largely inhibited by kn-93 contrasted to kn-92. there were little differences in parameters favoring eads such as monophasic action potential duration or heart rate in kn-92- or kn-93- treated hearts. cam kinase activity in situ increased 37% in hearts with eads compared to hearts without eads. this increase in cam kinase activity was prevented by pretreatment with kn-93. [1]in vitro, kn-93 potently suppressed rabbit myocardial cam kinase activity (calculated ki ≤ 2.58 μm), but the inactive analog kn-92 did not (ki > 100 μm). the actions of kn-93 and kn-92 on ica and other repolarizing k+currents did not illustrate preferential ead suppression by kn-93. [1]
References
1. kn-93, an inhibitor of multifunctional ca++/calmodulin-dependent protein kinase, decreases early afterdepolarizations in rabbit heart. j pharmacol exp ther. 1998 dec;287(3):996-1006.
KN-92 (hydrochloride) Preparation Products And Raw materials
Raw materials
Preparation Products
KN-92 (hydrochloride) Suppliers
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