4-broMo-7-fluoro-2,3-dihydroinden-1-one

Product Name: 4-broMo-7-fluoro-2,3-dihydroinden-1-one
CAS No.: 1003048-72-3
Chemical Name: 4-broMo-7-fluoro-2,3-dihydroinden-1-one
Synonyms: 4-BroMo-7-fluoro-2,3-dihydro-1H-inden-1-one;4-Bromo-7-fL;4-broMo-7-fluoro-2;4-Bromo-7-fluoro-1-indanone;4-Bromo-7-fluoroindan-1-one;4-bromo-7-fluoraindane-1-one;uoro-2,3-dihydro-1H-inden-1-one;4-broMo-7-fluoro-2,3-dihydroinden-1-one;4-Bromo-7-fluoro-2,3-dihydro-1-indanone;Bromo-7-fluoro-2,3-dihydro-1H-inden-1-one
CBNumber: CB82603344
Molecular Formula: C9H6BrFO
Formula Weight: 229.05
MOL File: 1003048-72-3.mol

More

Less

4-broMo-7-fluoro-2,3-dihydroinden-1-one Property

Boiling point:: 310.7±42.0 °C(Predicted)
Density: 1.691±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: solid
color: White to yellow
InChI: InChI=1S/C9H6BrFO/c10-6-2-3-7(11)9-5(6)1-4-8(9)12/h2-3H,1,4H2
InChIKey: HNXHWYGTXAJDEC-UHFFFAOYSA-N
SMILES: C1(=O)C2=C(C(Br)=CC=C2F)CC1

More

Less

Safety

HS Code: 2914390090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

More

Less

N-Bromosuccinimide Price

TRC

Product number: B688865
Product name: 4-Bromo-7-fluoro-2,3-dihydroinden-1-one
Packaging: 1g
Price: $495
Updated: 2021/12/16

TRC

Product number: B688865
Product name: 4-Bromo-7-fluoro-2,3-dihydroinden-1-one
Packaging: 2.5g
Price: $875
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0365783
Product name: 4-BROMO-7-FLUORO-2,3-DIHYDRO-1H-INDEN-1-ONE
Purity: 95.00%
Packaging: 5MG
Price: $500.38
Updated: 2021/12/16

Apolloscientific

Product number: PC49069
Product name: 4-Bromo-7-fluoroindan-1-one
Packaging: 1g
Price: $187
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2717-B-02
Product name: 4-Bromo-7-fluoroindan-1-one
Packaging: 1g
Price: $221
Updated: 2021/12/16

More

Less

4-broMo-7-fluoro-2,3-dihydroinden-1-one Chemical Properties,Usage,Production

Uses

4-?Bromo-?7-?fluoro-?2,?3-?dihydroinden-?1-?one is a reactant or reagent used in the preparation of indanyloxydihydrobenzofuranylacetic acids which are suitable for treatment of metabolic diseases.

Synthesis

651735-59-0

1003048-72-3

General procedure for the synthesis of 4-bromo-7-fluoroindanone using 7-fluoro-2,3-dihydro-1H-inden-1-one as starting material: 7-fluoro-2,3-dihydro-1H-inden-1-one (5.3 g, 35.3 mmol) was added to a solution of aluminum chloride (11.77 g, 88 mmol) in dichloroethane (100 mL) at room temperature, followed by a slow, dropwise addition of bromine ( 1.91 mL, 37.1 mmol). The reaction mixture was heated at 65 °C with stirring for 16 hours. Upon completion of the reaction, the mixture was cooled to room temperature and carefully poured into a mixture of ice and 1N aqueous hydrochloric acid solution. The mixture was extracted with ether (200 mL x 2) and the organic phases were combined. The organic phase was dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography with an eluent gradient of 0-10% ethyl acetate/hexane to give 4-bromo-7-fluoroindanone (5.2 g, 64% yield). The mass spectrum (DC1/NH3) showed m/z 246 (M + NH4)+.

References

[1] Patent: US2013/158067, 2013, A1. Location in patent: Paragraph 0540
[2] Patent: WO2018/172852, 2018, A1. Location in patent: Page/Page column 102; 103

4-broMo-7-fluoro-2,3-dihydroinden-1-one Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-broMo-7-fluoro-2,3-dihydroinden-1-one Suppliers

Austria 1 China 100 India 2 United Kingdom 1 United States 7 Global 111

Tongchuang Pharma(Suzhou). Co., Ltd.

Tel: 0512-63263366 18912765016
Fax: 0512-6326 3366
Email: tongtf110@sina.com
Country: China
ProdList: 993
Advantage: 62

Bellen Chemistry Co., Ltd.

Tel: 010-60400365-8001 15910885229
Fax: 010-60400361
Email: service@bellenchem.com
Country: China
ProdList: 4514
Advantage: 60

Suzhou Xinghuo Biotechnology Co., Ltd.

Tel: 19945655289
Email: xinghuoshengwu@163.com
Country: China
ProdList: 301
Advantage: 58

Suzhou Liyuan Biomedical Technology Co., Ltd.

Tel: 0557-18949975665 18949975665
Email: 1184800090@qq.com
Country: China
ProdList: 291
Advantage: 58

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Santai Labs, Inc.

Tel: 519-85601385
Fax: +86 519 8560 1389
Email: marketing@santailabs.com
Country: China
ProdList: 891
Advantage: 62

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Sci General Material & Chemical Ltd

Tel: 021-58388037;21-58388037 13472507714
Email: 35177634@qq.com;1589045147@qq.com
Country: China
ProdList: 803
Advantage: 55

Tianjin Derchemist Science & Technology Co., Ltd.

Tel: 22-58627059 13920586291
Fax: 022-58620305
Email: zdcomcon@126.com
Country: China
ProdList: 3829
Advantage: 50

More

Less

View Lastest Price from 4-broMo-7-fluoro-2,3-dihydroinden-1-one manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 4-broMo-7-fluoro-2,3-dihydroinden-1-one 1003048-72-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-16

Career Henan Chemical Co

Product: 4-broMo-7-fluoro-2,3-dihydroinden-1-one 1003048-72-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2019-07-11

1003048-72-3, 4-broMo-7-fluoro-2,3-dihydroinden-1-oneRelated Search:

Bromisoval 1-BroMoheptadecafluorooctane 4-BROMO-7-CHLORO-1-INDANONE 4-Bromo-7-methoxy-indan-1-one 4-Bromo-1-indanone 4-Bromo-5-chloro-2,3-dihydro-1H-inden-1-one 4-BROMO-6-FLUOROINDAN-1-ONE 4-Isopropylphenol

4-broMo-7-fluoro-2,3-dihydroinden-1-one

4-BroMo-7-fluoro-2,3-dihydro-1H-inden-1-one

4-Bromo-2,3-dihydro-7-fluoro-1H-inden-1-one, 4-Bromo-2,3-dihydro-7-fluoro-1-oxo-1H-indene

4-Bromo-7-fluoroindan-1-one

4-Bromo-7-fluoro-1-indanone

4-Bromo-7-fluoro-2,3-dihydro-1-indanone

4-Bromo-7-fL

uoro-2,3-dihydro-1H-inden-1-one

1H-Inden-1-one, 4-bromo-7-fluoro-2,3-dihydro-

4-broMo-7-fluoro-2

4-bromo-7-fluoraindane-1-one

Bromo-7-fluoro-2,3-dihydro-1H-inden-1-one

4-Bromo-7-fluoro-2,3-dihydro-1H-inden-1-one, 97%min

1003048-72-3