iMidazo[1,2-a]pyriMidine-6-carboxylic acid
- Product Name
- iMidazo[1,2-a]pyriMidine-6-carboxylic acid
- CAS No.
- 944896-64-4
- Chemical Name
- iMidazo[1,2-a]pyriMidine-6-carboxylic acid
- Synonyms
- iMidazo[1,2-a]pyriMidine-6-carboxylic acid
- CBNumber
- CB82659073
- Molecular Formula
- C7H5N3O2
- Formula Weight
- 163.13
- MOL File
- 944896-64-4.mol
iMidazo[1,2-a]pyriMidine-6-carboxylic acid Property
- Density
- 1.58±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- -0.43±0.41(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- I706998
- Product name
- Imidazo[1,2-a]pyrimidine-6-carboxylicacid
- Packaging
- 100mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- CS-0035932
- Product name
- Imidazo[1,2-a]pyrimidine-6-carboxylicacid
- Packaging
- 100mg
- Price
- $182
- Updated
- 2021/12/16
- Product number
- CS-0035932
- Product name
- Imidazo[1,2-a]pyrimidine-6-carboxylicacid
- Packaging
- 250mg
- Price
- $211
- Updated
- 2021/12/16
- Product number
- 2342AQ
- Product name
- IMIDAZO[1,2-A]PYRIMIDINE-6-CARBOXYLICACID
- Packaging
- 250mg
- Price
- $428
- Updated
- 2021/12/16
- Product number
- CS-0035932
- Product name
- Imidazo[1,2-a]pyrimidine-6-carboxylicacid
- Packaging
- 1g
- Price
- $528
- Updated
- 2021/12/16
iMidazo[1,2-a]pyriMidine-6-carboxylic acid Chemical Properties,Usage,Production
Synthesis
1083196-24-0
944896-64-4
Step 4. Add methyl imidazo[1,2-A]pyrimidine-6-carboxylate (92 g, 356.5 mmol) and water (200 mL) to a round bottom flask. An aqueous 6N NaOH solution (2.5 eq.) was added slowly and dropwise with stirring at room temperature. The reaction mixture was continued to be stirred at room temperature for 1 hr and then cooled in an ice water bath, followed by the addition of concentrated hydrochloric acid to adjust the pH to 5-6. The reaction solution was concentrated under reduced pressure to about 150 mL (3/4 of the original volume) and cooled again in an ice water bath. The precipitate precipitated was collected by vacuum filtration, washed with cold water (50 mL) and dried to give imidazo[1,2-A]pyrimidine-6-carboxylic acid as an off-white solid (46 g, 79% yield). The product was characterized by 1H NMR (DMSO-d6, 400 MHz): δ 9.29 (d, J = 2.0Hz, 1H), 8.89 (d, J = 2.0Hz, 1H), 7.94 (s, 1H), 7.70 (s, 1H). Mass spectrum (ESI-): m/z 164.1 [M + H]+, 186.1 [M + Na]+.
References
[1] Patent: WO2013/127266, 2013, A1. Location in patent: Page/Page column 130; 131
[2] Patent: WO2013/127267, 2013, A1. Location in patent: Page/Page column 82; 83
[3] Patent: WO2013/127269, 2013, A1. Location in patent: Page/Page column 144
[4] Patent: WO2013/127268, 2013, A1. Location in patent: Page/Page column 60; 61
[5] Patent: WO2013/130935, 2013, A1. Location in patent: Paragraph 0177
iMidazo[1,2-a]pyriMidine-6-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from iMidazo[1,2-a]pyriMidine-6-carboxylic acid manufacturers
- Product
- iMidazo[1,2-a]pyriMidine-6-carboxylic acid 944896-64-4
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-09