4-fluoro-2-Methoxy-5-nitroaniline

Product Name: 4-fluoro-2-Methoxy-5-nitroaniline
CAS No.: 1075705-01-9
Chemical Name: 4-fluoro-2-Methoxy-5-nitroaniline
Synonyms: 4-fluoro-2-methoxy;AZD9291 intermediates;uoro-2-methoxy-5-nitroaniL;4-Fluoro-2-mehoxy-5-nitroaniline;4-fluoro-2-Methoxy-5-nitroaniline;4-fluoro-2-methoxy-5-nitrophenylamine;4-Fluoro-2-Methoxy-5-nitrobenzenaMine;4-Fluoro-2-methoxy-5-nitroaniline 95+%;Benzenamine, 4-fluoro-2-methoxy-5-nitro-;4-fluoro-2-Methoxy-5-nitroaniline ISO 9001：2015 REACH
CBNumber: CB82670450
Molecular Formula: C7H7FN2O3
Formula Weight: 186.14
MOL File: 1075705-01-9.mol

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4-fluoro-2-Methoxy-5-nitroaniline Property

Melting point:: 130 °C
Boiling point:: 354.8±37.0 °C(Predicted)
Density: 1.412±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: powder to crystal
pka: 2.31±0.10(Predicted)
color: Light yellow to Brown
InChI: InChI=1S/C7H7FN2O3/c1-13-7-2-4(8)6(10(11)12)3-5(7)9/h2-3H,9H2,1H3
InChIKey: FYSIGSQCZXQTIH-UHFFFAOYSA-N
SMILES: C1(N)=CC([N+]([O-])=O)=C(F)C=C1OC

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Safety

HS Code: 2921420090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: F1246
Product name: 4-Fluoro-2-methoxy-5-nitroaniline
Packaging: 5G
Price: $33
Updated: 2024/03/01

TCI Chemical

Product number: F1246
Product name: 4-Fluoro-2-methoxy-5-nitroaniline
Packaging: 25G
Price: $98
Updated: 2024/03/01

TRC

Product number: F472455
Product name: 4-Fluoro-2-methoxy-5-nitroaniline
Packaging: 10g
Price: $140
Updated: 2021/12/16

TRC

Product number: F472455
Product name: 4-Fluoro-2-methoxy-5-nitroaniline
Packaging: 25g
Price: $275
Updated: 2021/12/16

AK Scientific

Product number: 9516AF
Product name: 4-Fluoro-2-methoxy-5-nitroaniline
Packaging: 100g
Price: $321
Updated: 2021/12/16

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4-fluoro-2-Methoxy-5-nitroaniline Chemical Properties,Usage,Production

Uses

4-Fluoro-2-methoxy-5-nitroaniline is used as a reagent for preparing the anticancer drug Mereletinib.

Synthesis

4-FLUORO-2-METHOXYANILINE(551 mg, 3.90 mmol) is dissolved in dichloromethane (39.0 mL), concentrated sulfuric acid (1.85 mL) is added dropwise with stirring under ice-cooling, and then concentrated nitric acid (267 μL, 5.85 mmol) is added dropwise. After stirring for 3 hours under ice-cooling, saturated aqueous sodium bicarbonate was added until pH 8 was reached. After washing with saturated aqueous sodium bicarbonate solution, washing with saturated brine, the organic layer was dried over sodium sulfate and evaporated under reduced pressure to obtain 675 mg of the 4-fluoro-2-Methoxy-5-nitroaniline (yield 93%).

4-fluoro-2-Methoxy-5-nitroaniline Preparation Products And Raw materials

Raw materials

Preparation Products

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4-fluoro-2-Methoxy-5-nitroaniline Suppliers

Americas 1 China 372 Europe 1 India 11 Japan 1 United Kingdom 1 United States 9 Global 396

AbaChemScene

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View Lastest Price from 4-fluoro-2-Methoxy-5-nitroaniline manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 4-fluoro-2-Methoxy-5-nitroaniline 1075705-01-9
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-12-02

Hebei Weibang Biotechnology Co., Ltd

Product: 4-fluoro-2-Methoxy-5-nitroaniline 1075705-01-9
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-22

Hebei Chuanghai Biotechnology Co,.LTD

Product: 4-Fluoro-2-Methoxy-5-Nitroaniline 1075705-01-9
Price: US $5.00-2.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-08-13

1075705-01-9, 4-fluoro-2-Methoxy-5-nitroanilineRelated Search:

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4-Fluoro-2-methoxy-5-nitroaniline 95+%

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AZD9291 intermediates

uoro-2-methoxy-5-nitroaniL

4-Fluoro-2-mehoxy-5-nitroaniline

4-fluoro-2-Methoxy-5-nitroaniline ISO 9001：2015 REACH

4-fluoro-2-methoxy-5-nitroaniline Molecular Formula: C7H7FN2O3 Molecular Weight: 186.14

4-fluoro-2-methoxy

1075705-01-9

075705-01-9

AZD9291

API

1075705-01-9