ChemicalBook > CAS DataBase List > N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea

N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea

Product Name
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea
CAS No.
1129683-83-5
Chemical Name
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea
Synonyms
Sorafenib Impurity 65;Sorafenib impurities5;Sorafenib impurities166;Sorafenib related coMpound 4;1-(4-chloro-3-(trifluromethyl)phenyl)-3-(4-hydroxyphenyl)urea;N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea;N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea;Urea, N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)-;Sorafenib impurity 17/1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-hydroxyphenyl)urea
CBNumber
CB82707215
Molecular Formula
C14H10ClF3N2O2
Formula Weight
330.69
MOL File
1129683-83-5.mol
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N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea Property

Boiling point:
350.1±42.0 °C(Predicted)
Density 
1.547±0.06 g/cm3(Predicted)
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
10.16±0.26(Predicted)
color 
White to Light Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
C596195
Product name
1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea
Packaging
100mg
Price
$950
Updated
2021/12/16
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N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea Chemical Properties,Usage,Production

Uses

1-(4-Chloro-3-trifluoromethylphenyl)-3-(4-hydroxyphenyl)urea is an impurity of Sorafenib (S676850), a kinase inhibitor targeting both RAF kinase and receptor tyrosine kinases that promote angiogensis.

N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea Preparation Products And Raw materials

Raw materials

Preparation Products

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N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea Suppliers

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1129683-83-5, N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)ureaRelated Search:

Sorafenib Impurity 6 Sorafenib IMpurity C 4-(4-Aminophenoxy)-N-methylpicolinamide Sorafenib related coMpound 1 Sorafenib Related Compound 13 Sorafenib related coMpound 5 Sorafenib Impurity 1 Sorafenib Related Compound 21 Sorafenib related compound 10 Sorafenib related coMpound 8 Sorafenib related compound 11 N-Methyl-4-chloropyridine-2-carboxamide Sorafenib Related Compound 22 Sorafenib related coMpound 6 1-(4-chloro-3-(trifluoromethyl)phenyl)urea ETHYL 4-CHLORO-3-TRIFLUOROMETHYLCARBANILATE 4-Chloro-alpha,alpha,alpha-trifluoro-m-toluidine Sorafenib related coMpound 7

  • Sorafenib related coMpound 4
  • 1-(4-chloro-3-(trifluromethyl)phenyl)-3-(4-hydroxyphenyl)urea
  • Sorafenib impurity 17/1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-hydroxyphenyl)urea
  • N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea
  • Sorafenib Impurity 65
  • Sorafenib impurities166
  • Sorafenib impurities5
  • Urea, N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)-
  • N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-(4-hydroxyphenyl)urea
  • 1129683-83-5