ChemicalBook > CAS DataBase List > 1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)

1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)

Product Name
1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)
CAS No.
200880-42-8
Chemical Name
1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)
Synonyms
18:0 PG;DSPG Sodium Salt;Sodium distearoyl phosphatidylglycerol;L-α-Phosphatidyl-DL-glycerol, distearoyl;1,2-Distearoyl-sn-glycero-3-PG (sodium salt);1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium);1,2-Distearoyl-sn-glycero-3-phosphorylglycerol sodium salt;1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt);1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt);Sodium (2R)-2,3-Bis(stearoyloxy)propyl 2,3-Dihydroxypropyl Phosphate
CBNumber
CB82719898
Molecular Formula
C81H159Na2O16P
Formula Weight
1466.072861
MOL File
200880-42-8.mol
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1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt) Property

storage temp. 
-20°C
solubility 
Chloroform:Methanol:Water = 2:1:0.1 (Very Slightly)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
55845
Product name
1,2-Distearoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium salt
Purity
≥97.0% (TLC)
Packaging
100mg
Price
$226
Updated
2023/01/07
Sigma-Aldrich
Product number
55845
Product name
1,2-Distearoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium salt
Purity
≥97.0% (TLC)
Packaging
1g
Price
$954
Updated
2023/01/07
TCI Chemical
Product number
D5648
Product name
1,2-Dioctadecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) Sodium Salt
Packaging
250MG
Price
$252
Updated
2025/07/31
Cayman Chemical
Product number
15087
Product name
1,2-Distearoyl-sn-glycero-3-PG (sodium salt)
Purity
≥98%
Packaging
100mg
Price
$60
Updated
2022/04/27
Cayman Chemical
Product number
15087
Product name
1,2-Distearoyl-sn-glycero-3-PG (sodium salt)
Purity
≥98%
Packaging
250mg
Price
$135
Updated
2022/04/27
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1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt) Chemical Properties,Usage,Production

Description

DSPG, also known as 1,2-Distearoyl-sn-glycero-3-phosphoglycerol, is a phospholipid molecule with phosphate polar head connected to two non-polar lipid (stearic acid) by a glycerol molecule. In water, the molecule can orient itself into lipid bilayer and can be used for drug encapsulation, such as drug loaded liposomes or nanoparticles.

Uses

1,2-Distearoyl-sn-glycero-3-phospho-rac-(1-glycerol) Sodium Salt is used to prepare polyethyleneglycol-modified liposomal doxorubicin for therapies against drug resistant tumors. It is also used in the PEGylated liposomal drug formulation of the anti-cancer agent oxaliplatin.

in vivo

1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (DSPG) sodium can be used to prepare negatively charged nanoliposomes. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium nanoliposome formulations correct dyslipidaemia and inhibit the progression of atherosclerosis in rabbits fed a high cholesterol diet[1].

1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt) Preparation Products And Raw materials

Raw materials

Preparation Products

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1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt) Suppliers

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200880-42-8, 1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)Related Search:

1,2-Distearoyl-sn-glycero-3-phosphocholine 1,2-DI[CIS-9-OCTADECENOYL]-SN-GLYCERO-3-PHOSPHATE SODIUM SALT 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHATIDIC ACID, SODIUM SALT 1-PALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine 1,2-DI 3,7,11,15-TETRAMETHYLHEXADECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE L-BETA,GAMMA-DIPALMITOYL-ALPHA-PHOSPHATIDIC ACID DISODIUM SALT L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROYL 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine 1-MYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE SODIUM SALT 1,2-dioleoyl-sn-glycero-3-phospho-L-serine (sodiuM salt) 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHO-L-SERINE (MONOSODIUM SALT) 1,2-DiMyristoyl-sn-glycero-3-phospho-rac-(1-glycerol) SodiuM Salt 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHOCHOLINE 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATIDYL-RAC-GLYCEROL, NA SALT 1,2-DI[(CIS)-9-OCTADECENOYL]-SN-GLYCEROL-3-PHOSPHO-[1-RAC-GLYCEROL] SODIUM SALT

  • 1,2-Dioctadecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) sodium salt
  • L-α-Phosphatidyl-DL-glycerol, distearoyl
  • Octadecanoic acid (1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester monosodium salt
  • 1,2-Distearoyl-sn-glycero-3-PG (sodium salt)
  • 1,2-DISTEAROYL-SN-GLYCERO-3-PHOSPHO-(1'-RAC-GLYCEROL) (SODIUM SALT);18:0 PG;DSPG;PG(18:0/18:0)
  • 18:0 PG
  • 1,2-Dioctadecanoyl-sn-glycero-3-phospho-(1′-rac-glycerol) sodium salt, 1,2-Distearoyl-sn-glycero-3-phosphoglycerol, L -α-Phosphatidyl-DL-glycerol, distearoyl, DSPG-Na, Octadecanoic acid (1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-eth
  • 1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)(DSPG)
  • 1,2-Distearoyl-sn-glycero-3-phosphorylglycerol sodium salt
  • DSPG Sodium Salt
  • Sodium (2R)-2,3-Bis(stearoyloxy)propyl 2,3-Dihydroxypropyl Phosphate
  • sodium [(2R)-2,3-bis(1-oxooctadecoxy)propyl] 2,3-dihydroxypropyl phosphate
  • Sodium (R)-2,3-bis(stearoyloxy)propyl (2,3-dihydroxypropyl) phosphate
  • 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium)
  • 1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)
  • Sodium distearoyl phosphatidylglycerol
  • 1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodiuM salt)
  • Octadecanoicacid,1,1′-[(1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl]ester,sodiumsalt(1:1)
  • 200880-42-8