BLU9931

Product Name: BLU9931
CAS No.: 1538604-68-0
Chemical Name: BLU9931
Synonyms: BLU;BLU9931;LM-3610;CS-1699;BLU-9931;BLU 9931;LM-3610; BLU9931;BLU 9931;BLU-9931;BLU-9931;BLU 9931;BLU9931;BLU9931, 98%, a potent, selective, and irreversible FGFR4 inhibitor
CBNumber: CB82741679
Molecular Formula: C26H22Cl2N4O3
Formula Weight: 509.38
MOL File: 1538604-68-0.mol

More

Less

BLU9931 Property

Density: 1.361±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: ≥50.9 mg/mL in DMSO; insoluble in H2O; ≥2.53 mg/mL in EtOH with gentle warming and ultrasonic
form: Powder
pka: 13.15±0.70(Predicted)
color: Off-white to light yellow

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 18405
Product name: BLU9931
Purity: ≥98%
Packaging: 1mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 18405
Product name: BLU9931
Purity: ≥98%
Packaging: 5mg
Price: $216
Updated: 2024/03/01

Cayman Chemical

Product number: 18405
Product name: BLU9931
Purity: ≥98%
Packaging: 10mg
Price: $380
Updated: 2024/03/01

Cayman Chemical

Product number: 18405
Product name: BLU9931
Purity: ≥98%
Packaging: 25mg
Price: $711
Updated: 2024/03/01

AK Scientific

Product number: 4064DW
Product name: N-[2-[[6-(2,6-Dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino]-3-methylphenyl]prop-2-enamide
Packaging: 10mg
Price: $185
Updated: 2021/12/16

More

Less

BLU9931 Chemical Properties,Usage,Production

Definition

BLU9931 is a potent, highly selective, and irreversible fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC50 of 3 nM and a Kd of 6 nM. BLU9931 has significant antitumor activity. BLU9931 makes a covalent bond with Cys552 within the ATP-binding pocket of FGFR4, which is not present in FGFR1-3. BLU9931 inhibited gastric cancer cell growth in a transplanted mouse model[1].

References

[1] Norihiko Sasaki. “FGFR4 Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer.” Cancers (2020).

BLU9931 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

BLU9931 Suppliers

China 123 India 1 United States 11 Global 135

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

ApexBio Technology

Tel: --
Fax: --
Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

Active Biopharma Corp

Tel: --
Fax: --
Email: support@activebiopharma.com
Country: United States
ProdList: 82
Advantage: 0

More

Less

View Lastest Price from BLU9931 manufacturers

Career Henan Chemical Co

Product: BLU 9931 1538604-68-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000KGS
Release date: 2019-12-31

1538604-68-0, BLU9931Related Search:

Pralsetinib 1 NM-PP1 ZLN005 Esomeprazole magnesium Tariquidar Palbociclib IXABEPILONE PF-04929113 4-(6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl)-2-((1r,4r)-4-hydroxycyclohexylamino)benzamide L-4-THIAZOLYLALANINE Ilomastat AZD-1208 Crenolanib Doxorubicin hydrochloride AZD6738 2-(2-Chlorophenyl)-4-(3-(diMethylaMino)phenyl)-5-Methyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione Enasidenib RVX-208

BLU 9931

BLU9931

BLU-9931

LM-3610

LM-3610; BLU9931

2-Propenamide,N-[2-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-quinazolinyl]amino]-3-methylphenyl]-

BLU 9931;BLU-9931

BLU9931, 98%, a potent, selective, and irreversible FGFR4 inhibitor

N-(2-((6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl)amino)-3-methylphenyl)acrylamide

N-[2-[[6-(2,6-Dichloro-3,5-dimethoxyphenyl)-2-quinazolinyl]amino]-3-methylphenyl]-2-propenamide

BLU

CS-1699

BLU-9931;BLU 9931;BLU9931

1538604-68-0

C26H22Cl2N4O3

Inhibitors