4-(4-Morpholinobutylthio)phenol
- Product Name
- 4-(4-Morpholinobutylthio)phenol
- CAS No.
- 57055-82-0
- Chemical Name
- 4-(4-Morpholinobutylthio)phenol
- Synonyms
- MoTP;33N14;4-(4-Morpholinobutylthio)phenol;4-(4-morpholin-4-ylbutylsulfanyl)phenol;Phenol, 4-[[4-(4-morpholinyl)butyl]thio]-
- CBNumber
- CB82750473
- Molecular Formula
- C14H21NO2S
- Formula Weight
- 267.39
- MOL File
- 57055-82-0.mol
4-(4-Morpholinobutylthio)phenol Property
- storage temp.
- -20°C
- solubility
- DMSO: ≥80mg/mL
- form
- powder
- color
- white to tan
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- SML0047
- Product name
- MoTP
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $99.75
- Updated
- 2025/07/31
- Product number
- SML0047
- Product name
- MoTP
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $329
- Updated
- 2025/07/31
- Product number
- 15204
- Product name
- MoTP
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 15204
- Product name
- MoTP
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $86
- Updated
- 2024/03/01
- Product number
- 15204
- Product name
- MoTP
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $139
- Updated
- 2024/03/01
4-(4-Morpholinobutylthio)phenol Chemical Properties,Usage,Production
Description
MoTP (57055-82-0) specifically ablates zebrafish larval melanocytes. Melanocytotoxicity is dependent on tyrosinase activity.1,2 MoTP is a useful tool for elucidating melanocyte stem cell regeneration, recruitment and maintenance.3-5
Uses
MoTP is a specific platelet activating factor receptor antagonist and can induce melanocyte ablation. MoTP can be used for the research of cancer.
References
[1] CHAO-TSUNG YANG Stephen L J. Small molecule-induced ablation and subsequent regeneration of larval zebrafish melanocytes.[J]. Development, 2006, 133 18: 3563-3573. DOI:10.1242/dev.02533
[2] CHAO-TSUNG YANG. Mutations in gfpt1 and skiv2l2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish.[J]. PLoS Genetics, 2007, 3 6: e88. DOI:10.1371/journal.pgen.0030088
[3] KEITH A HULTMAN. Defects in ErbB-dependent establishment of adult melanocyte stem cells reveal independent origins for embryonic and regeneration melanocytes.[J]. PLoS Genetics, 2009: e1000544. DOI:10.1371/journal.pgen.1000544
[4] KEITH A. HULTMAN Stephen L J. Differential contribution of direct-developing and stem cell-derived melanocytes to the zebrafish larval pigment pattern[J]. Developmental biology, 2010, 337 2: Pages 425-431. DOI:10.1016/j.ydbio.2009.11.019
[5] KEITH A HULTMAN S L J Alexander W Scott. Small molecule modifier screen for kit-dependent functions in zebrafish embryonic melanocytes.[J]. Zebrafish, 2008, 5 4 1: 279-287. DOI:10.1089/zeb.2008.0542
4-(4-Morpholinobutylthio)phenol Preparation Products And Raw materials
Raw materials
Preparation Products
4-(4-Morpholinobutylthio)phenol Suppliers
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 52923
- Advantage
- 58
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- Fax
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- sales@focusbiomolecules.com
- Country
- United States
- ProdList
- 1284
- Advantage
- 58
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- cayman@caymanchem.com
- Country
- United States
- ProdList
- 6213
- Advantage
- 81
- Tel
- --
- Fax
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- Country
- United States
- ProdList
- 6773
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