2-Methylpyrrolidine Property

Melting point:

-96.37°C (estimate)

Boiling point:

97-99 °C/744 mmHg (lit.)

Density 

0.834 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.437(lit.)

Flash point:

37 °F

storage temp. 

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

pka

10.93±0.10(Predicted)

form 

Liquid

color 

Clear colorless to light yellow

Water Solubility 

soluble

InChI

InChI=1S/C5H11N/c1-5-3-2-4-6-5/h5-6H,2-4H2,1H3

InChIKey

RGHPCLZJAFCTIK-UHFFFAOYSA-N

SMILES

N1CCCC1C

CAS DataBase Reference

765-38-8(CAS DataBase Reference)

NIST Chemistry Reference

2-Methylpyrrolidine(765-38-8)

EPA Substance Registry System

Pyrrolidine, 2-methyl- (765-38-8)

Safety

Hazard Codes 

F,C

Risk Statements 

11-34-22

Safety Statements 

16-26-36/37/39-45

RIDADR 

UN 2924 3/PG 2

WGK Germany 

3

TSCA 

Yes

HazardClass 

3

PackingGroup 

II

HS Code 

29339900

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

2-Methylpyrrolidine Chemical Properties,Usage,Production

Chemical Properties

clear colorless to light yellow liquid

Uses

2-Methylpyrrolidine can be used to produce?2-(2-methylpyrrolidinyl)benzaldehyde?at the temperature of?152°C. It is commonly used as organic reagent.

Definition

ChEBI: 2-methylpyrrolidine is a member of the class of pyrrolidines that is pyrrolidine which is substituted by a methyl group at position 2. It has a role as a plant metabolite.

Application

2-Methylpyrrolidine is an inhibitor of cyclooxygenase-2 (COX-2) and a key component in the preparation of other organic intermediates. 2-Methylpyrrolidine may be used as a guest molecule for the synthesis of nonasil-[4¹5^8], a clatharate compound.

General Description

2-Methylpyrrolidine is a substituted pyrrolidine. It is one of the major bioactive compounds found in Teucrium manghuaense. The hydrodenitrogenation of 2-methylpyrrolidine in the presence of sulfided NiMo/γ-Al₂O₃ catalyst has been studied.