2,2'-Dibromodiethyl ether
Uses- Product Name
- 2,2'-Dibromodiethyl ether
- CAS No.
- 5414-19-7
- Chemical Name
- 2,2'-Dibromodiethyl ether
- Synonyms
- 1-BROMO-2-(2-BROMOETHOXY)ETHANE;BIS(2-BROMOETHYL) ETHER;2-bromoethyl;2-BROMOETHYL ETHER;CAS_5414-19-7;Bis(2-bromoethyL;Br-PEG1-CH2CH2Br;Bromo-PEG1-bromide;2-Bromoethyl Ester;DI(2-BROMOETHYL)ETHER
- CBNumber
- CB8292636
- Molecular Formula
- C4H8Br2O
- Formula Weight
- 231.91
- MOL File
- 5414-19-7.mol
2,2'-Dibromodiethyl ether Property
- Boiling point:
- 92-93 °C12 mm Hg(lit.)
- Density
- 1.845 g/mL at 25 °C(lit.)
- refractive index
- 1.513
- Flash point:
- 185 °F
- storage temp.
- 2-8°C
- solubility
- Chloroform (Soluble), Methanol (Slightly)
- form
- clear liquid
- color
- Colorless to Light yellow to Light orange
- Specific Gravity
- 1.845
- Water Solubility
- Not miscible or difficult to mix with water.
- BRN
- 1098335
- Stability:
- This product may also contain 2-chloroethyl ether (CAS 111-44-4) or N,N-dimethylformamide (CAS 68-12-2) MSDS data for these materials should be consulted before use. Combustible. Incompatible with oxidizing agents, acid chlorides, chloroformates, reducing agents, halogens.
- CAS DataBase Reference
- 5414-19-7(CAS DataBase Reference)
- NIST Chemistry Reference
- 1-Bromo-2-(2-bromoethoxy)ethane(5414-19-7)
- EPA Substance Registry System
- Ethane, 1,1'-oxybis[2-bromo- (5414-19-7)
Safety
- Hazard Codes
- T,Xi
- Risk Statements
- 61-37/38-41
- Safety Statements
- 53-26-36/37/39-45
- RIDADR
- 2810
- WGK Germany
- 3
- TSCA
- Y
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29091990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 95254
- Product name
- Bis(2-bromoethyl) ether
- Purity
- technical, ≥95% (GC)
- Packaging
- 10ml
- Price
- $179
- Updated
- 2025/07/31
- Product number
- 95254
- Product name
- Bis(2-bromoethyl) ether
- Purity
- technical, ≥95% (GC)
- Packaging
- 50mL
- Price
- $603
- Updated
- 2025/07/31
- Product number
- 382205
- Product name
- 2-Bromoethyl ether
- Purity
- technical grade, 90%
- Packaging
- 5ml
- Price
- $93.1
- Updated
- 2025/07/31
- Product number
- 382205
- Product name
- 2-Bromoethyl ether
- Purity
- technical grade, 90%
- Packaging
- 25ml
- Price
- $205.1
- Updated
- 2025/07/31
- Product number
- B3752
- Product name
- Bis(2-bromoethyl) Ether
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $32
- Updated
- 2025/07/31
2,2'-Dibromodiethyl ether Chemical Properties,Usage,Production
Uses
2,2'-dibromodiethyl ether is an important organic intermediate (building block) to synthetize substituted diethyl ether products.
Description
Bis(2-bromoethyl) ether is an either compound with two terminal bromine atoms. Bis(2-bromoethyl) ether can be used as a building block for variety of pharmaceutical compounds and mateials.
Chemical Properties
colourless liquid
Uses
2-Bromoethyl ether (2,2′-Dibromodiethyl ether) may be used in the preparation of 1,4,7-trioxa-10-19-dithia-13,16-diaza-12,17-dioxo-8,9,14,15,20,21-tribenzoheneicosane.
General Description
2-Bromoethyl ether (2,2′-Dibromodiethyl ether) is a halogen containing ether. 2,2′-Dibromodiethyl ether has been prepared by reacting dioxane with anhydrous, bromine free hydrogen bromide.
Synthesis
111-46-6
5414-19-7
General procedure for the synthesis of 2,2'-dibromodiethyl ether from diethylene glycol: 21.2 g (0.2 mol) of diethylene glycol was added to a dry 1 L three-necked flask, followed by the addition of 500 mL of carbon tetrachloride as a solvent, and a magnetic stirrer was turned on to dissolve the ingredients completely. The reaction system was cooled in an ice-water bath to 0 °C. Under stirring conditions, 60 g (0.22 mol) of phosphorus tribromide was slowly added dropwise using a constant-pressure dropping funnel, with the rate of dropwise acceleration being controlled to avoid intense exotherm. After the dropwise addition, the reaction was continued in an ice-water bath with stirring for 1 hour. Subsequently, the ice-water bath was withdrawn and the reaction mixture was allowed to warm up naturally to room temperature with continuous stirring for 15 h to ensure complete reaction. Upon completion of the reaction, the carbon tetrachloride solvent was removed by concentration under reduced pressure by rotary evaporator. To the residue, 500 mL of ethyl acetate was added for dissolution, followed by four washes with 5% aqueous sodium carbonate to neutralize the residual acid. The organic layer was separated and dried with anhydrous sodium sulfate. Finally, the ethyl acetate was removed by distillation under reduced pressure to give 41.4 g of the target product 2,2'-dibromodiethyl ether as a colorless oil.
IC 50
Alkyl-Chain
References
[1] Journal of Materials Chemistry B, 2014, vol. 2, # 29, p. 4640 - 4652
[2] Journal of Materials Chemistry B, 2015, vol. 3, # 8, p. 1495 - 1506
[3] Journal of Organic Chemistry, 1983, vol. 48, # 20, p. 3412 - 3422
[4] Journal of the American Chemical Society, 1937, vol. 59, p. 213
[5] Justus Liebigs Annalen der Chemie, 1937, vol. 528, p. 150
2,2'-Dibromodiethyl ether Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,2'-Dibromodiethyl ether manufacturers
- Product
- 2,2"-Dibromodiethyl ether 5414-19-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 2,2"-Dibromodiethyl ether 5414-19-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- 2,2'-Dibromodiethyl ether 5414-19-7
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg,5kg,50kg
- Release date
- 2020-01-18