ChemicalBook > CAS DataBase List > 2,2'-Dibromodiethyl ether

2,2'-Dibromodiethyl ether

Uses

Product Name: 2,2'-Dibromodiethyl ether
CAS No.: 5414-19-7
Chemical Name: 2,2'-Dibromodiethyl ether
Synonyms: 1-BROMO-2-(2-BROMOETHOXY)ETHANE;BIS(2-BROMOETHYL) ETHER;2-bromoethyl;2-BROMOETHYL ETHER;CAS_5414-19-7;Bis(2-bromoethyL;Br-PEG1-CH2CH2Br;Bromo-PEG1-bromide;2-Bromoethyl Ester;DI(2-BROMOETHYL)ETHER
CBNumber: CB8292636
Molecular Formula: C4H8Br2O
Formula Weight: 231.91
MOL File: 5414-19-7.mol

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2,2'-Dibromodiethyl ether Property

Boiling point:: 92-93 °C12 mm Hg(lit.)
Density: 1.845 g/mL at 25 °C(lit.)
refractive index: 1.513
Flash point:: 185 °F
storage temp.: 2-8°C
solubility: Chloroform (Soluble), Methanol (Slightly)
form: clear liquid
color: Colorless to Light yellow to Light orange
Specific Gravity: 1.845
Water Solubility: Not miscible or difficult to mix with water.
BRN: 1098335
Stability:: This product may also contain 2-chloroethyl ether (CAS 111-44-4) or N,N-dimethylformamide (CAS 68-12-2) MSDS data for these materials should be consulted before use. Combustible. Incompatible with oxidizing agents, acid chlorides, chloroformates, reducing agents, halogens.
CAS DataBase Reference: 5414-19-7(CAS DataBase Reference)
NIST Chemistry Reference: 1-Bromo-2-(2-bromoethoxy)ethane(5414-19-7)
EPA Substance Registry System: Ethane, 1,1'-oxybis[2-bromo- (5414-19-7)

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Safety

Hazard Codes: T,Xi
Risk Statements: 61-37/38-41
Safety Statements: 53-26-36/37/39-45
RIDADR: 2810
WGK Germany: 3
TSCA: Y
HazardClass: 6.1
PackingGroup: III
HS Code: 29091990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 95254
Product name: Bis(2-bromoethyl) ether
Purity: technical, ≥95% (GC)
Packaging: 10ml
Price: $179
Updated: 2025/07/31

Sigma-Aldrich

Product number: 95254
Product name: Bis(2-bromoethyl) ether
Purity: technical, ≥95% (GC)
Packaging: 50mL
Price: $603
Updated: 2025/07/31

Sigma-Aldrich

Product number: 382205
Product name: 2-Bromoethyl ether
Purity: technical grade, 90%
Packaging: 5ml
Price: $93.1
Updated: 2025/07/31

Sigma-Aldrich

Product number: 382205
Product name: 2-Bromoethyl ether
Purity: technical grade, 90%
Packaging: 25ml
Price: $205.1
Updated: 2025/07/31

TCI Chemical

Product number: B3752
Product name: Bis(2-bromoethyl) Ether
Purity: >98.0%(GC)
Packaging: 5g
Price: $32
Updated: 2025/07/31

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2,2'-Dibromodiethyl ether Chemical Properties,Usage,Production

Uses

2,2'-dibromodiethyl ether is an important organic intermediate (building block) to synthetize substituted diethyl ether products.

Description

Bis(2-bromoethyl) ether is an either compound with two terminal bromine atoms. Bis(2-bromoethyl) ether can be used as a building block for variety of pharmaceutical compounds and mateials.

Chemical Properties

colourless liquid

Uses

2-Bromoethyl ether (2,2′-Dibromodiethyl ether) may be used in the preparation of 1,4,7-trioxa-10-19-dithia-13,16-diaza-12,17-dioxo-8,9,14,15,20,21-tribenzoheneicosane.

General Description

2-Bromoethyl ether (2,2′-Dibromodiethyl ether) is a halogen containing ether. 2,2′-Dibromodiethyl ether has been prepared by reacting dioxane with anhydrous, bromine free hydrogen bromide.

Synthesis

111-46-6

5414-19-7

General procedure for the synthesis of 2,2'-dibromodiethyl ether from diethylene glycol: 21.2 g (0.2 mol) of diethylene glycol was added to a dry 1 L three-necked flask, followed by the addition of 500 mL of carbon tetrachloride as a solvent, and a magnetic stirrer was turned on to dissolve the ingredients completely. The reaction system was cooled in an ice-water bath to 0 °C. Under stirring conditions, 60 g (0.22 mol) of phosphorus tribromide was slowly added dropwise using a constant-pressure dropping funnel, with the rate of dropwise acceleration being controlled to avoid intense exotherm. After the dropwise addition, the reaction was continued in an ice-water bath with stirring for 1 hour. Subsequently, the ice-water bath was withdrawn and the reaction mixture was allowed to warm up naturally to room temperature with continuous stirring for 15 h to ensure complete reaction. Upon completion of the reaction, the carbon tetrachloride solvent was removed by concentration under reduced pressure by rotary evaporator. To the residue, 500 mL of ethyl acetate was added for dissolution, followed by four washes with 5% aqueous sodium carbonate to neutralize the residual acid. The organic layer was separated and dried with anhydrous sodium sulfate. Finally, the ethyl acetate was removed by distillation under reduced pressure to give 41.4 g of the target product 2,2'-dibromodiethyl ether as a colorless oil.

IC 50

Alkyl-Chain

References

[1] Journal of Materials Chemistry B, 2014, vol. 2, # 29, p. 4640 - 4652
[2] Journal of Materials Chemistry B, 2015, vol. 3, # 8, p. 1495 - 1506
[3] Journal of Organic Chemistry, 1983, vol. 48, # 20, p. 3412 - 3422
[4] Journal of the American Chemical Society, 1937, vol. 59, p. 213
[5] Justus Liebigs Annalen der Chemie, 1937, vol. 528, p. 150

2,2'-Dibromodiethyl ether Preparation Products And Raw materials

Raw materials

Preparation Products

4-(3-BROMOPHENYL)MORPHOLINE

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View Lastest Price from 2,2'-Dibromodiethyl ether manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2,2"-Dibromodiethyl ether 5414-19-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 2,2"-Dibromodiethyl ether 5414-19-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: 2,2'-Dibromodiethyl ether 5414-19-7
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg,5kg,50kg
Release date: 2020-01-18

5414-19-7, 2,2'-Dibromodiethyl etherRelated Search:

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CAS_5414-19-7

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B,B'-DIBROMODIETHYL ETHER

BIS(2-BROMOETHYL) ETHER

Bis(2-bromomethyl)ether

1,1'-OXYBIS(2-BROMOETHANE)

1-BROMO-2-(2-BROMOETHOXY)ETHANE

2-Bromoethyl Ester

2-Bromoethyl ether~2,2-Dibromodiethyl ether

Bis(2-bromoethyl) ether(stabilized with water)

3-Oxa-1,5-dibromopentane

Bis(2-bromoethyl) Ether &gt

Bis(2-bromomethyl)ether-96%

2-Bromoethyl ether, 90%,

2,2'-Dibromodiethyl ether

Bis(2-bromoethyl) ether, 98%

2,2'-Dibromodiethyl ether

Br-PEG1-CH2CH2Br

5414-19-7

BrCH2CH2OCH2CH2Br

C4H8Br2O

BrCH2CH22O

Building Blocks

Oxygen Compounds

Organic Building Blocks

Ethers

Aliphatics

Halides

Ethers

Organic Building Blocks

Oxygen Compounds