13-Oxo-9E,11E-octadecadienoic acid
- Product Name
- 13-Oxo-9E,11E-octadecadienoic acid
- CAS No.
- 29623-29-8
- Chemical Name
- 13-Oxo-9E,11E-octadecadienoic acid
- Synonyms
- 13-Oxo-9E;11E-octadecadienoic acid;13-Oxo-9E,11E-octadecadienoic acid;(9E,11E)-13-Oxo-9,11-octadecadienoic acid;13-Oxo-trans-9,trans-11-octadecadienoic acid;13-Oxo-9E,11E-octadecadienoic acid USP/EP/BP;9,11-Octadecadienoic acid, 13-oxo-, (9E,11E)-;13Oxo9E,11Eoctadecadienoic acid,13 Oxo 9E,11E octadecadienoic acid
- CBNumber
- CB83051427
- Molecular Formula
- C18H30O3
- Formula Weight
- 294.43
- MOL File
- 29623-29-8.mol
13-Oxo-9E,11E-octadecadienoic acid Property
- Boiling point:
- 425.5±18.0 °C(Predicted)
- Density
- 0.966±0.06 g/cm3(Predicted)
- pka
- 4.78±0.10(Predicted)
- form
- Solid
- color
- White to off-white
13-Oxo-9E,11E-octadecadienoic acid Chemical Properties,Usage,Production
Uses
13-Oxo-9E,11E-octadecadienoic acid, an isomer of 9-oxo-ODA, is a potent PPARα activator derived from tomato juice. 13-Oxo-9E,11E-octadecadienoic acid decreases plasma and hepatic triglyceride in obese diabetic mice[1].
Definition
ChEBI: 13-oxo-9E,11E-ODE is an oxooctadecadienoic acid that consists of 9E,11E-octadecadienoic acid with the oxo substituent located at position 13. It has a role as a metabolite. It is an oxo fatty acid and a 13-oxo-9,11-octadecadienoic acid.
in vivo
13-Oxo-9E,11E-octadecadienoic acid (feed; 0.02% and 0.05%; for 4 weeks) improves dyslipidemia and lowering TG content in the liver and skeletal muscle of HFD-fed KK-Ay mice[1].
| Animal Model: | Male KK-Ay mice with 4-week-old[1] |
| Dosage: | 0.02% and 0.05% |
| Administration: | Feed; for 4 weeks |
| Result: | Improved dyslipidemia and lowering TG content in the liver and skeletal muscle of HFD-fed KK-Ay mice. |
IC 50
PPARα
References
[1] Kim YI, et al. Potent PPARα activator derived from tomato juice, 13-oxo-9,11-octadecadienoic acid, decreasesplasma and hepatic triglyceride in obese diabetic mice. PLoS One. 2012;7(2):e31317. DOI:10.1371/journal.pone.0031317
13-Oxo-9E,11E-octadecadienoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 13-Oxo-9E,11E-octadecadienoic acid manufacturers
- Product
- 13-Oxo-9E,11E-octadecadienoic acid 29623-29-8
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-04-30
- Product
- 13-Oxo-9E,11E-octadecadienoic acid 29623-29-8
- Price
- US $3.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1kg,5kg,50kg
- Release date
- 2020-01-18