m-PEG4-Mal
- Product Name
- m-PEG4-Mal
- CAS No.
- 1263044-81-0
- Chemical Name
- m-PEG4-Mal
- Synonyms
- 4-MAL;m-PEG4-Mal;m-dPEG4-MAL;m-dPEG??-MAL;m-dPEG(R)4-MAL;MeO-PEG(4)-mal;mPEG4-Maleimide;m-PEG4-amido-Mal;m-PEG4-amino-Mal;Mal-amido-PEG4-Ome
- CBNumber
- CB83062573
- Molecular Formula
- C16H26N2O7
- Formula Weight
- 358.39
- MOL File
- 1263044-81-0.mol
m-PEG4-Mal Property
- storage temp.
- -20°C
- form
- solid or viscous liquid
- InChIKey
- DOHTYEHHGXSUJO-UHFFFAOYSA-N
- SMILES
- O=C1C=CC(N1CCC(NCCOCCOCCOCCOC)=O)=O
Safety
- WGK Germany
- WGK 3
- Storage Class
- 11 - Combustible Solids
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- QBD10745
- Product name
- m-dPEG®4-MAL
- Packaging
- 100MG
- Price
- $343
- Updated
- 2026/03/19
- Product number
- QBD10745
- Product name
- m-dPEG®4-MAL
- Packaging
- 1000MG
- Price
- $604
- Updated
- 2023/06/20
- Product number
- P999823
- Product name
- m-PEG4-Mal
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 10745
- Product name
- m-dPEG®₄-MAL
- Packaging
- 100mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- PEG2375
- Product name
- MeO-PEG(4)-mal
- Packaging
- 100mg
- Price
- $432
- Updated
- 2021/12/16
m-PEG4-Mal Chemical Properties,Usage,Production
Description
m-PEG4-Mal is a PEG linker containing a maleimide group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
m-PEG4-amino-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
reaction suitability
reactivity: thiol reactive
reagent type: chemical modification reagent
reagent type: cross-linking reagent
reactivity: sulfhydryl reactive
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
m-PEG4-Mal Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from m-PEG4-Mal manufacturers
- Product
- m-PEG4-amido-Mal 1263044-81-0
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-27