ChemicalBook > CAS DataBase List > Loxoprofen

Loxoprofen

Product Name
Loxoprofen
CAS No.
68767-14-6
Chemical Name
Loxoprofen
Synonyms
IOXOPROFEN;2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid;2-[4-(2-OXO-CYCLOPENTYLMETHYL)-PHENYL]-PROPIONIC ACID;A-METHYL-4-[(2-OXOCYCLOPENTYL)METHYL]BENZENEACETIC ACID;KOLOXO;LOXOPROFEN;Loxoprofene;Loxoprofeno;Loxoprofen-d6;Loxoprofen RS
CBNumber
CB8311755
Molecular Formula
C15H18O3
Formula Weight
246.31
MOL File
68767-14-6.mol
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Loxoprofen Property

Melting point:
108.5-111°
Boiling point:
bp0.3 190-195°
Density 
1.182±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
solid
pka
4.39±0.10(Predicted)
color 
White to Off-White
Merck 
14,5589
InChI
InChI=1S/C15H18O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13H,2-4,9H2,1H3,(H,17,18)
InChIKey
YMBXTVYHTMGZDW-UHFFFAOYSA-N
SMILES
C(C1CCCC1=O)C1C=CC(C(C)C(=O)O)=CC=1
CAS DataBase Reference
68767-14-6(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
2918.99.3000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L0664
Product name
Loxoprofen
Packaging
5mg
Price
$386
Updated
2024/03/01
TCI Chemical
Product number
L0244
Product name
Loxoprofen
Purity
>97.0%(HPLC)(T)
Packaging
5g
Price
$108
Updated
2024/03/01
TRC
Product number
L472905
Product name
Loxoprofen
Packaging
100mg
Price
$185
Updated
2021/12/16
AK Scientific
Product number
F995
Product name
Loxoprofen
Packaging
5g
Price
$127
Updated
2021/12/16
ChemScene
Product number
CS-2760
Product name
Loxoprofen
Purity
99.76%
Packaging
200mg
Price
$144
Updated
2021/12/16
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Loxoprofen Chemical Properties,Usage,Production

Uses

antiinflammatory, analgesic

Uses

Loxoprofen is a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Loxoprofen becomes active after metabolism in the body and inhibits the activation of cyclooxygenase.

Definition

ChEBI: A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-[(2-oxocyclopentyl)methyl]phenyl group. A prodrug that is rapidly converted to its active trans-alcohol metabolite following ora administration.

Loxoprofen Preparation Products And Raw materials

Raw materials

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester ETHYL PHENYLPROPIOLATE Cyclopentanecarboxylic acid

Preparation Products

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Loxoprofen Suppliers

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View Lastest Price from Loxoprofen manufacturers

Hebei Dangtong Import and export Co LTD
Product
Loxoprofen 68767-14-6
Price
US $100.00-95.00/kg
Min. Order
1kg
Purity
99.99%
Supply Ability
100Tons
Release date
2023-03-17
Henan Fengda Chemical Co., Ltd
Product
Loxoprofen 68767-14-6
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-16
Shaanxi Dideu Medichem Co. Ltd
Product
Loxoprofen 68767-14-6
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-04-29

68767-14-6, LoxoprofenRelated Search:

Chlorodimethylphenylsilane Kresoxim-methyl Methyl salicylate Methylcyclopentane Methanol Methylparaben Tribenuron methyl Tri(o-tolyl)phosphine Propionic acid Methyl acrylate PHENYL VALERATE 2,2-Bis(hydroxymethyl)propionic acid Basic Violet 1 Cyclopentane Silicone oil (high temperature) Loxoprofen Related Compound 5 Loxoprofen Related Compound 13 2-[(4-Acetylphenyl)methyl]cyclopentan-1-one

  • IOXOPROFEN
  • 2-[4-[(2-Oxocyclopentan-1-yl)methyl]phenyl]propionic acid
  • KOLOXO
  • LOXOPROFEN
  • 2-[4-(2-OXO-CYCLOPENTYLMETHYL)-PHENYL]-PROPIONIC ACID
  • A-METHYL-4-[(2-OXOCYCLOPENTYL)METHYL]BENZENEACETIC ACID
  • α-methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid
  • 2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid
  • ALPHA-METHYL-4-[(2-OXOCYCLOPENTYL)METHYL]BENZENEACETIC ACID
  • Benzeneacetic acid, a-methyl-4-[(2-oxocyclopentyl)methyl]- (9CI)
  • Loxoprofen (base and/or unspecified salts)
  • α-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid, Koloxo
  • Loxoprofen (high-melting polymorph)
  • Loxoprofen (low-melting polymorph)
  • 2-[p-(2-Oxocyclopentylmethyl)phenyl]propionic acid
  • 2-[4-[(2-ketocyclopentyl)methyl]phenyl]propionic acid
  • Loxoprofen USP
  • Loxoprofen See L472900
  • Benzeneacetic acid, a-Methyl-4-[(2-oxocyclopentyl)Methyl]-
  • Loxoprofen-d6
  • Loxoprofen RS
  • Loxoprofene
  • Loxoprofeno
  • Benzeneacetic acid, α-methyl-4-[(2-oxocyclopentyl)methyl]-
  • Loxoprofen USP/EP/BP
  • Loxoprofen (10mM in DMSO)
  • Loxoprofen Impurity 67
  • Loxoprofen Impurity 68
  • Loxoprofen D7
  • Loxoprofen-d3Q: What is Loxoprofen-d3 Q: What is the CAS Number of Loxoprofen-d3
  • Loxoprofen API
  • Benzeneacetic acid, α-methyl-4-[(2-oxocyclopentyl)methyl]-
  • 2-(4-((2-(hydroxymethyl)-1,4-dioxaspiro[4.4]nonan-6-yl)methyl)phenyl)propanoic acid
  • 68767-14-6
  • LOXONIN
  • Active Pharmaceutical Ingredients