ChemicalBook > CAS DataBase List > Loxoprofen

Loxoprofen

Product Name
Loxoprofen
CAS No.
68767-14-6
Chemical Name
Loxoprofen
Synonyms
IOXOPROFEN;2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid;2-[4-(2-OXO-CYCLOPENTYLMETHYL)-PHENYL]-PROPIONIC ACID;A-METHYL-4-[(2-OXOCYCLOPENTYL)METHYL]BENZENEACETIC ACID;KOLOXO;LOXOPROFEN;Loxoprofene;Loxoprofeno;Loxoprofen-d6;Loxoprofen RS
CBNumber
CB8311755
Molecular Formula
C15H18O3
Formula Weight
246.31
MOL File
68767-14-6.mol
More
Less

Loxoprofen Property

Melting point:
108.5-111°
Boiling point:
bp0.3 190-195°
Density 
1.182±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
solid
pka
4.39±0.10(Predicted)
color 
White to Off-White
Merck 
14,5589
InChI
InChI=1S/C15H18O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13H,2-4,9H2,1H3,(H,17,18)
InChIKey
YMBXTVYHTMGZDW-UHFFFAOYSA-N
SMILES
C(C1CCCC1=O)C1C=CC(C(C)C(=O)O)=CC=1
CAS DataBase Reference
68767-14-6(CAS DataBase Reference)
More
Less

Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
2918.99.3000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L0664
Product name
Loxoprofen
Packaging
5mg
Price
$386
Updated
2024/03/01
TCI Chemical
Product number
L0244
Product name
Loxoprofen
Purity
>97.0%(HPLC)(T)
Packaging
5g
Price
$108
Updated
2024/03/01
TRC
Product number
L472905
Product name
Loxoprofen
Packaging
100mg
Price
$185
Updated
2021/12/16
AK Scientific
Product number
F995
Product name
Loxoprofen
Packaging
5g
Price
$127
Updated
2021/12/16
ChemScene
Product number
CS-2760
Product name
Loxoprofen
Purity
99.76%
Packaging
200mg
Price
$144
Updated
2021/12/16
More
Less

Loxoprofen Chemical Properties,Usage,Production

Uses

antiinflammatory, analgesic

Uses

Loxoprofen is a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Loxoprofen becomes active after metabolism in the body and inhibits the activation of cyclooxygenase.

Definition

ChEBI: A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-[(2-oxocyclopentyl)methyl]phenyl group. A prodrug that is rapidly converted to its active trans-alcohol metabolite following ora administration.

Loxoprofen Preparation Products And Raw materials

Raw materials

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid ethyl ester ETHYL PHENYLPROPIOLATE Cyclopentanecarboxylic acid

Preparation Products

More
Less

Loxoprofen Suppliers

Americas 1 China 287 Europe 4 Germany 2 India 12 Japan 1 Switzerland 2 United Kingdom 5 United States 34 Global 348
Wuhan Boye Technology Development Co., Ltd.
Tel
027-81625225 15377010747
Fax
027-81625225
Email
hui@boyechemicals.com
Country
China
ProdList
480
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8843
Advantage
52
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Synches Co., Ltd.
Tel
021-53292253
Fax
021-53292253
Email
biz@synches.com
Country
China
ProdList
199
Advantage
64
TaiZhou ZhiCheng Chemicals & Technology Co., LTD.
Tel
0523-82837785 13914525028
Fax
0523-87913272
Email
info@jszchg.com
Country
China
ProdList
249
Advantage
60
Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2872
Advantage
58
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5653
Advantage
65
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Shanghai T&W Pharmaceutical Co., Ltd.
Tel
+86 21 61551611
Fax
+86 21 50676805
Country
China
ProdList
9891
Advantage
58
Nanjing Norris-Pharm Technology Co., Ltd
Tel
13901585132
Fax
+86-25-52131256
Email
799750417@qq.com
Country
China
ProdList
8878
Advantage
55
SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD.
Tel
021-34666753 13311639313
Fax
+86-21-34979012
Email
info@shyrchem.com
Country
China
ProdList
571
Advantage
55
Haoyuan Chemexpress Co., Ltd.
Tel
021-58950125
Fax
(86) 21-58955996
Email
info@chemexpress.com
Country
China
ProdList
7552
Advantage
61
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9545
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4428
Advantage
55
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3239
Advantage
55
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Shanghai DiBai Chemicals Co., Ltd.
Tel
021-54359730 400-008-9730
Fax
021-54353864
Email
info@chemxyz.com
Country
China
ProdList
3991
Advantage
60
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9346
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5875
Advantage
58
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
16166
Advantage
55
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9906
Advantage
50
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
11481
Advantage
59
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9793
Advantage
50
Shanghai Yongye Biotechnology Co., Ltd.
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8144
Advantage
55
AdooQ Bioscience CHINA
Tel
025-58849295 18951903616;
Fax
025-68650336
Email
info@adooq.cn
Country
China
ProdList
2990
Advantage
60
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9756
Advantage
58
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9484
Advantage
50
Guangzhou Ciming Biological Technology Co., Ltd.
Tel
020-38082199,29065168,38082986,29878298,29866629,4000192398
Fax
+86 (20)38082986
Country
China
ProdList
830
Advantage
60
Hangzhou Milestone Pharmtech Co., Ltd.
Tel
0571-82896630 18969958410
Email
sales_hz@milestonepharmtech.com
Country
China
ProdList
4852
Advantage
55
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-66023220 0086-15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
7850
Advantage
55
Sinfachem Limited.
Tel
025-84683399 13952017251
Email
sinfachem@foxmail.com
Country
China
ProdList
268
Advantage
58
Guangzhou Qianguang Trade Co., Ltd.
Tel
020-39071117 18030085485
Fax
020-39071119
Email
2797782741@qq.com
Country
China
ProdList
291
Advantage
55
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10453
Advantage
58
Artis Biotech Co. Ltd.
Tel
0575-18780151478 18582380095
Fax
0575-89298961
Email
sales@artisbio.com
Country
China
ProdList
2964
Advantage
58
Guangzhou QiYun Biotechnology Co., Ltd.
Tel
020-61288194 61288195
Fax
020-61288700
Email
505721671@qq.com
Country
China
ProdList
3866
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27313
Advantage
60
Radiant Pharma & Tech. Co., Ltd
Tel
T:15050866711
Fax
QQ:2677337387
Email
wanglin.chen@radiant-pharma.com
Country
China
ProdList
466
Advantage
60
Changzhou Baokang Pharmaceutical & Chemical Co.,Ltd.
Tel
0519-0519-88494757 15961115886
Fax
+86-519-83756102
Email
sales@baokangchem.com
Country
China
ProdList
97
Advantage
60
Raw material medicin reagent co.,Ltd
Tel
Email
sales@njromanme.com
Country
China
ProdList
4529
Advantage
58
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8011
Advantage
62
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 4009686088
Email
3193328036@qq.com
Country
China
ProdList
29785
Advantage
68
Shenzhen Simeiquan Biotechnology Co. Ltd
Tel
18126413629 0755-23311925 2355327053
Fax
0755-23311925
Email
abel@ycgmp.com
Country
China
ProdList
5113
Advantage
58
More
Less

View Lastest Price from Loxoprofen manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Loxoprofen Acid 68767-14-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%min
Supply Ability
500kg/month
Release date
2021-06-19
Shaanxi Dideu Medichem Co. Ltd
Product
Loxoprofen 68767-14-6
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-04-29
Hebei Yanxi Chemical Co., Ltd.
Product
Loxoprofen 68767-14-6
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20T
Release date
2023-03-10

68767-14-6, LoxoprofenRelated Search:

Chlorodimethylphenylsilane Kresoxim-methyl Methyl salicylate Methylcyclopentane Methanol Methylparaben Tribenuron methyl Tri(o-tolyl)phosphine Propionic acid Methyl acrylate PHENYL VALERATE 2,2-Bis(hydroxymethyl)propionic acid Basic Violet 1 Cyclopentane Silicone oil (high temperature) Loxoprofen Related Compound 5 Loxoprofen Related Compound 13 2-[(4-Acetylphenyl)methyl]cyclopentan-1-one

  • IOXOPROFEN
  • 2-[4-[(2-Oxocyclopentan-1-yl)methyl]phenyl]propionic acid
  • KOLOXO
  • LOXOPROFEN
  • 2-[4-(2-OXO-CYCLOPENTYLMETHYL)-PHENYL]-PROPIONIC ACID
  • A-METHYL-4-[(2-OXOCYCLOPENTYL)METHYL]BENZENEACETIC ACID
  • α-methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid
  • 2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid
  • ALPHA-METHYL-4-[(2-OXOCYCLOPENTYL)METHYL]BENZENEACETIC ACID
  • Benzeneacetic acid, a-methyl-4-[(2-oxocyclopentyl)methyl]- (9CI)
  • Loxoprofen (base and/or unspecified salts)
  • α-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid, Koloxo
  • Loxoprofen (high-melting polymorph)
  • Loxoprofen (low-melting polymorph)
  • 2-[p-(2-Oxocyclopentylmethyl)phenyl]propionic acid
  • 2-[4-[(2-ketocyclopentyl)methyl]phenyl]propionic acid
  • Loxoprofen USP
  • Loxoprofen See L472900
  • Benzeneacetic acid, a-Methyl-4-[(2-oxocyclopentyl)Methyl]-
  • Loxoprofen-d6
  • Loxoprofen RS
  • Loxoprofene
  • Loxoprofeno
  • Benzeneacetic acid, α-methyl-4-[(2-oxocyclopentyl)methyl]-
  • Loxoprofen USP/EP/BP
  • Loxoprofen (10mM in DMSO)
  • Loxoprofen Impurity 67
  • Loxoprofen Impurity 68
  • Loxoprofen D7
  • Loxoprofen-d3Q: What is Loxoprofen-d3 Q: What is the CAS Number of Loxoprofen-d3
  • Loxoprofen API
  • Benzeneacetic acid, α-methyl-4-[(2-oxocyclopentyl)methyl]-
  • 2-(4-((2-(hydroxymethyl)-1,4-dioxaspiro[4.4]nonan-6-yl)methyl)phenyl)propanoic acid
  • 68767-14-6
  • LOXONIN
  • Active Pharmaceutical Ingredients