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Loxoprofen

Product Name
Loxoprofen
CAS No.
68767-14-6
Chemical Name
Loxoprofen
Synonyms
IOXOPROFEN;2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid;2-[4-(2-OXO-CYCLOPENTYLMETHYL)-PHENYL]-PROPIONIC ACID;A-METHYL-4-[(2-OXOCYCLOPENTYL)METHYL]BENZENEACETIC ACID;KOLOXO;LOXOPROFEN;Loxoprofene;Loxoprofeno;Loxoprofen-d6;Loxoprofen RS
CBNumber
CB8311755
Molecular Formula
C15H18O3
Formula Weight
246.31
MOL File
68767-14-6.mol
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Loxoprofen Property

Melting point:
108.5-111°
Boiling point:
bp0.3 190-195°
Density 
1.182±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
solid
pka
4.39±0.10(Predicted)
color 
White to Off-White
Merck 
14,5589
InChI
InChI=1S/C15H18O3/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16/h5-8,10,13H,2-4,9H2,1H3,(H,17,18)
InChIKey
YMBXTVYHTMGZDW-UHFFFAOYSA-N
SMILES
C(C1CCCC1=O)C1C=CC(C(C)C(=O)O)=CC=1
CAS DataBase Reference
68767-14-6(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
2918.99.3000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L0664
Product name
Loxoprofen
Packaging
5mg
Price
$386
Updated
2024/03/01
TCI Chemical
Product number
L0244
Product name
Loxoprofen
Purity
>97.0%(HPLC)(T)
Packaging
5g
Price
$108
Updated
2024/03/01
TRC
Product number
L472905
Product name
Loxoprofen
Packaging
100mg
Price
$185
Updated
2021/12/16
AK Scientific
Product number
F995
Product name
Loxoprofen
Packaging
5g
Price
$127
Updated
2021/12/16
ChemScene
Product number
CS-2760
Product name
Loxoprofen
Purity
99.76%
Packaging
200mg
Price
$144
Updated
2021/12/16
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Loxoprofen Chemical Properties,Usage,Production

Uses

antiinflammatory, analgesic

Uses

Loxoprofen is a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. Loxoprofen becomes active after metabolism in the body and inhibits the activation of cyclooxygenase.

Definition

ChEBI: A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-[(2-oxocyclopentyl)methyl]phenyl group. A prodrug that is rapidly converted to its active trans-alcohol metabolite following ora administration.

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Loxoprofen Suppliers

Wuhan Boye Technology Development Co., Ltd.
Tel
027-81625225 15377010747
Fax
027-81625225
Email
hui@boyechemicals.com
Country
China
ProdList
480
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8843
Advantage
52
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Synches Co., Ltd.
Tel
021-53292253
Fax
021-53292253
Email
biz@synches.com
Country
China
ProdList
199
Advantage
64
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View Lastest Price from Loxoprofen manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Loxoprofen Acid 68767-14-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%min
Supply Ability
500kg/month
Release date
2021-06-19
Shaanxi Dideu Medichem Co. Ltd
Product
Loxoprofen 68767-14-6
Price
US $1.00-1.00/KG
Min. Order
1g
Purity
99%
Supply Ability
50tons
Release date
2020-04-29
Hebei Yanxi Chemical Co., Ltd.
Product
Loxoprofen 68767-14-6
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20T
Release date
2023-03-10

68767-14-6, LoxoprofenRelated Search:


  • IOXOPROFEN
  • 2-[4-[(2-Oxocyclopentan-1-yl)methyl]phenyl]propionic acid
  • KOLOXO
  • LOXOPROFEN
  • 2-[4-(2-OXO-CYCLOPENTYLMETHYL)-PHENYL]-PROPIONIC ACID
  • A-METHYL-4-[(2-OXOCYCLOPENTYL)METHYL]BENZENEACETIC ACID
  • α-methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid
  • 2-{4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid
  • ALPHA-METHYL-4-[(2-OXOCYCLOPENTYL)METHYL]BENZENEACETIC ACID
  • Benzeneacetic acid, a-methyl-4-[(2-oxocyclopentyl)methyl]- (9CI)
  • Loxoprofen (base and/or unspecified salts)
  • α-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid, Koloxo
  • Loxoprofen (high-melting polymorph)
  • Loxoprofen (low-melting polymorph)
  • 2-[p-(2-Oxocyclopentylmethyl)phenyl]propionic acid
  • 2-[4-[(2-ketocyclopentyl)methyl]phenyl]propionic acid
  • Loxoprofen USP
  • Loxoprofen See L472900
  • Benzeneacetic acid, a-Methyl-4-[(2-oxocyclopentyl)Methyl]-
  • Loxoprofen-d6
  • Loxoprofen RS
  • Loxoprofene
  • Loxoprofeno
  • Benzeneacetic acid, α-methyl-4-[(2-oxocyclopentyl)methyl]-
  • Loxoprofen USP/EP/BP
  • Loxoprofen (10mM in DMSO)
  • Loxoprofen Impurity 67
  • Loxoprofen Impurity 68
  • Loxoprofen D7
  • Loxoprofen-d3Q: What is Loxoprofen-d3 Q: What is the CAS Number of Loxoprofen-d3
  • Loxoprofen API
  • Benzeneacetic acid, α-methyl-4-[(2-oxocyclopentyl)methyl]-
  • 2-(4-((2-(hydroxymethyl)-1,4-dioxaspiro[4.4]nonan-6-yl)methyl)phenyl)propanoic acid
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