PD168393

ChemicalBook > CAS DataBase List > PD168393

Product Name: PD168393
CAS No.: 194423-15-9
Chemical Name: PD168393
Synonyms: CS-2316;PD 168393;PD168393 USP/EP/BP;PD-168393;PD 168393;PD168393;PD-168393;PD 168393;4-[(3-BROMOPHENYL)AMINO]-6-ACRYLAMIDOQUINAZOLINE;N-[4-(3-Bromoanilino)quinazolin-6-yl]prop-2-enamide;N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide;N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-propenamide;2-Propenamide, N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-
CBNumber: CB8316129
Molecular Formula: C17H13BrN4O
Formula Weight: 369.22
MOL File: Mol file

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PD168393 Property

Melting point:: 279℃
Boiling point:: 571.1±50.0 °C(Predicted)
Density: 1.558±0.06 g/cm3(Predicted)
storage temp.: room temp
solubility: insoluble in H2O; ≥1 mg/mL in EtOH with gentle warming and ultrasonic; ≥18.45 mg/mL in DMSO
form: powder
pka: 12.19±0.43(Predicted)
color: white to beige

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 513033
Product name: PD 168393 - CAS 194423-15-9 - Calbiochem
Packaging: 1mg
Price: $201
Updated: 2024/03/01

Sigma-Aldrich

Product number: PZ0285
Product name: PD168393
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $115
Updated: 2023/06/20

Sigma-Aldrich

Product number: PZ0285
Product name: PD168393
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $451
Updated: 2023/06/20

Cayman Chemical

Product number: 21059
Product name: PD 168393
Purity: ≥95%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 21059
Product name: PD 168393
Purity: ≥95%
Packaging: 5mg
Price: $100
Updated: 2024/03/01

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PD168393 Chemical Properties,Usage,Production

Uses

PD 168393, is an irreversible epidermal growth factor receptor (EGFR) inhibitor.

Uses

PD168393 has been used in the acute inhibition of ErbB4.

Definition

ChEBI: A member of the class of quinazolines carrying bromoanilino and acrylamido substituents at positions 4 and 6 respectively.

Biochem/physiol Actions

PD168393 is a 6-acrylamido-4-anilinoquinazoline compound. It increases apoptosis in malignant peripheral nerve sheath tumor cells, stimulated by lysosomal dysfunction.

target

EGFR

PD168393 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from PD168393 manufacturers

Career Henan Chemical Co

Product: PD168393 194423-15-9
Price: US $1.00/EA
Min. Order: 100g
Purity: 99%
Supply Ability: G/KG/T
Release date: 2019-12-20

194423-15-9, PD168393Related Search:

PD 166866 PD153035 HCl AG 1478 HYDROCHLORIDE DAPH AG 18 LAVENDUSTIN A METHYL 2,5-DIHYDROXYCINNAMATE H-ARG-ARG-LEU-ILE-GLU-ASP-ASN-GLU-TYR-THR-ALA-ARG-GLY-OH AG 825 TYRPHOSTIN A25 Canertinib Sotrastaurin Tofacitinib citrate PELITINIB Erlotinib hydrochloride TYRPHOSTIN A51 AG 213 PD 158780

4-[(3-BROMOPHENYL)AMINO]-6-ACRYLAMIDOQUINAZOLINE

PD 168393

N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-propenamide

PD168393;PD-168393;PD 168393

CS-2316

N-[4-(3-Bromoanilino)quinazolin-6-yl]prop-2-enamide

PD-168393;PD 168393

2-Propenamide, N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-

N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide

PD168393 USP/EP/BP

194423-15-9

Inhibitors