ChemicalBook > CAS DataBase List > PD168393

PD168393

Product Name
PD168393
CAS No.
194423-15-9
Chemical Name
PD168393
Synonyms
CS-2316;PD 168393;PD168393 USP/EP/BP;PD-168393;PD 168393;PD 168393, EGFR inhibitor;PD168393;PD-168393;PD 168393;4-[(3-BROMOPHENYL)AMINO]-6-ACRYLAMIDOQUINAZOLINE;N-[4-(3-Bromoanilino)quinazolin-6-yl]prop-2-enamide;N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide;N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-propenamide
CBNumber
CB8316129
Molecular Formula
C17H13BrN4O
Formula Weight
369.22
MOL File
Mol file
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PD168393 Property

Melting point:
279℃
Boiling point:
571.1±50.0 °C(Predicted)
Density 
1.558±0.06 g/cm3(Predicted)
storage temp. 
room temp
solubility 
insoluble in H2O; ≥1 mg/mL in EtOH with gentle warming and ultrasonic; ≥18.45 mg/mL in DMSO
form 
powder
pka
12.19±0.43(Predicted)
color 
white to beige
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
513033
Product name
PD 168393 - CAS 194423-15-9 - Calbiochem
Packaging
1mg
Price
$201
Updated
2024/03/01
Sigma-Aldrich
Product number
PZ0285
Product name
PD168393
Purity
≥98% (HPLC)
Packaging
5MG
Price
$115
Updated
2023/06/20
Sigma-Aldrich
Product number
PZ0285
Product name
PD168393
Purity
≥98% (HPLC)
Packaging
25MG
Price
$451
Updated
2023/06/20
Cayman Chemical
Product number
21059
Product name
PD 168393
Purity
≥95%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
21059
Product name
PD 168393
Purity
≥95%
Packaging
5mg
Price
$100
Updated
2024/03/01
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PD168393 Chemical Properties,Usage,Production

Uses

PD 168393, is an irreversible epidermal growth factor receptor (EGFR) inhibitor.

Uses

PD168393 has been used in the acute inhibition of ErbB4.

Definition

ChEBI: A member of the class of quinazolines carrying bromoanilino and acrylamido substituents at positions 4 and 6 respectively.

Biochem/physiol Actions

PD168393 is a 6-acrylamido-4-anilinoquinazoline compound. It increases apoptosis in malignant peripheral nerve sheath tumor cells, stimulated by lysosomal dysfunction.

target

EGFR

PD168393 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from PD168393 manufacturers

Career Henan Chemical Co
Product
PD168393 194423-15-9
Price
US $1.00/EA
Min. Order
100g
Purity
99%
Supply Ability
G/KG/T
Release date
2019-12-20

194423-15-9, PD168393Related Search:


  • 4-[(3-BROMOPHENYL)AMINO]-6-ACRYLAMIDOQUINAZOLINE
  • PD 168393
  • N-[4-[(3-Bromophenyl)amino]-6-quinazolinyl]-2-propenamide
  • PD168393;PD-168393;PD 168393
  • CS-2316
  • N-[4-(3-Bromoanilino)quinazolin-6-yl]prop-2-enamide
  • PD-168393;PD 168393
  • 2-Propenamide, N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-
  • N-(4-((3-Bromophenyl)amino)quinazolin-6-yl)acrylamide
  • PD168393 USP/EP/BP
  • PD 168393, EGFR inhibitor
  • 194423-15-9
  • Inhibitors