ChemicalBook > CAS DataBase List > (+)-Biotin-PEG8-NHS Ester
(+)-Biotin-PEG8-NHS Ester
- Product Name
- (+)-Biotin-PEG8-NHS Ester
- CAS No.
- 2143968-03-8
- Chemical Name
- (+)-Biotin-PEG8-NHS Ester
- Synonyms
- Biotin-PEG8-SPA;(+)-Biotin-PEG8-NHS Ester;2,5-Dioxopyrrolidin-1-yl 29-oxo-33-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10,13,16,19,22,25-octaoxa-28-azatritriacontanoate;4,7,10,13,16,19,22,25-Octaoxa-28-azatritriacontanoic acid, 33-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-29-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
- CBNumber
- CB83311639
- Molecular Formula
- C33H56N4O14S
- Formula Weight
- 764.88
- MOL File
- 2143968-03-8.mol
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(+)-Biotin-PEG8-NHS Ester Property
- Density
- 1.29±0.1 g/cm3(Predicted)
- pka
- 13.90±0.40(Predicted)
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
purepeg
- Product number
- 246908
- Product name
- (+)-Biotin-PEG8-NHSEster
- Purity
- min.95%
- Packaging
- 50mg
- Price
- $140
- Updated
- 2021/12/16
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(+)-Biotin-PEG8-NHS Ester Chemical Properties,Usage,Production
Uses
Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biological Activity
Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
(+)-Biotin-PEG8-NHS Ester Preparation Products And Raw materials
Raw materials
Preparation Products
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(+)-Biotin-PEG8-NHS Ester Suppliers
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View Lastest Price from (+)-Biotin-PEG8-NHS Ester manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Biotin-PEG8-NHS ester 2143968-03-8
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >98.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-30
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