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(+)-Biotin-PEG8-NHS Ester

Product Name
(+)-Biotin-PEG8-NHS Ester
CAS No.
2143968-03-8
Chemical Name
(+)-Biotin-PEG8-NHS Ester
Synonyms
Biotin-PEG8-SPA;(+)-Biotin-PEG8-NHS Ester;2,5-Dioxopyrrolidin-1-yl 29-oxo-33-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10,13,16,19,22,25-octaoxa-28-azatritriacontanoate;4,7,10,13,16,19,22,25-Octaoxa-28-azatritriacontanoic acid, 33-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-29-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber
CB83311639
Molecular Formula
C33H56N4O14S
Formula Weight
764.88
MOL File
2143968-03-8.mol
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(+)-Biotin-PEG8-NHS Ester Property

Density 
1.29±0.1 g/cm3(Predicted)
pka
13.90±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

purepeg
Product number
246908
Product name
(+)-Biotin-PEG8-NHSEster
Purity
min.95%
Packaging
50mg
Price
$140
Updated
2021/12/16
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(+)-Biotin-PEG8-NHS Ester Chemical Properties,Usage,Production

Biological Activity

Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

(+)-Biotin-PEG8-NHS Ester Preparation Products And Raw materials

Raw materials

Preparation Products

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(+)-Biotin-PEG8-NHS Ester Suppliers

T&W GROUP
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021-61551611 13296011611
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+86 21-50676805
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contact@trustwe.com
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China
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9895
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Borenpharm Co., Ltd
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027-65563561
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86-27-59218822
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sales@borenpharm.com
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China
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1245
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Changzhou Hopschain Chemical Co.,Ltd.
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0519-85528066 13775048983
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0519-85528066
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sales@hopschem.com
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China
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Jinan elephant international trading co., LTD
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Fax
-
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13006575422@163.com
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China
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6355
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Zhengzhou Acme Chemical Co., Ltd.
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0371-0371-55629727 13323845623
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037155629727
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2885676761@qq.com
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China
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10009
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Hangzhou HanLai Biochemical Technology Co., Ltd.
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571-86101219 18768477782
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sales09@leobiochem.com
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China
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Xi'an Confluore Biological Technology Co., Ltd.
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+86-156-80926068 +86-15680926068
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1924344760@qq.com
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China
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4824
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TargetMol Chemicals Inc.
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+1-781-999-5354 +1-00000000000
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marketing@targetmol.com
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United States
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32165
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Wuhan Borenpharm Co., Ltd
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027-65563561 18717150066
Fax
027-59218822
Email
3207347307@qq.com
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CHINA
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1238
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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
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029-86217788 13892832556
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China
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1993
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View Lastest Price from (+)-Biotin-PEG8-NHS Ester manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Biotin-PEG8-NHS ester 2143968-03-8
Price
US $0.00/mg
Min. Order
500mg
Purity
>98.00%
Supply Ability
500mg
Release date
2024-03-30

2143968-03-8, (+)-Biotin-PEG8-NHS EsterRelated Search:


  • (+)-Biotin-PEG8-NHS Ester
  • Biotin-PEG8-SPA
  • 4,7,10,13,16,19,22,25-Octaoxa-28-azatritriacontanoic acid, 33-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-29-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
  • 2,5-Dioxopyrrolidin-1-yl 29-oxo-33-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10,13,16,19,22,25-octaoxa-28-azatritriacontanoate
  • 2143968-03-8
  • SiChem
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