ChemicalBook > CAS DataBase List > (+)-Biotin-PEG8-NHS Ester

(+)-Biotin-PEG8-NHS Ester

Product Name
(+)-Biotin-PEG8-NHS Ester
CAS No.
2143968-03-8
Chemical Name
(+)-Biotin-PEG8-NHS Ester
Synonyms
Biotin-PEG8-SPA;(+)-Biotin-PEG8-NHS Ester;2,5-Dioxopyrrolidin-1-yl 29-oxo-33-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10,13,16,19,22,25-octaoxa-28-azatritriacontanoate;4,7,10,13,16,19,22,25-Octaoxa-28-azatritriacontanoic acid, 33-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-29-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber
CB83311639
Molecular Formula
C33H56N4O14S
Formula Weight
764.88
MOL File
2143968-03-8.mol
More
Less

(+)-Biotin-PEG8-NHS Ester Property

Density 
1.29±0.1 g/cm3(Predicted)
pka
13.90±0.40(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

purepeg
Product number
246908
Product name
(+)-Biotin-PEG8-NHSEster
Purity
min.95%
Packaging
50mg
Price
$140
Updated
2021/12/16
More
Less

(+)-Biotin-PEG8-NHS Ester Chemical Properties,Usage,Production

Biological Activity

Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

(+)-Biotin-PEG8-NHS Ester Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(+)-Biotin-PEG8-NHS Ester Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Apollo Scientific Ltd
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United States
ProdList
3254
Advantage
58
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
PurePEG,LLC
Tel
--
Fax
--
Email
info@purepeg.com
Country
United States
ProdList
697
Advantage
58
More
Less

View Lastest Price from (+)-Biotin-PEG8-NHS Ester manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Biotin-PEG8-NHS ester 2143968-03-8
Price
US $0.00/mg
Min. Order
500mg
Purity
>98.00%
Supply Ability
500mg
Release date
2024-03-30

2143968-03-8, (+)-Biotin-PEG8-NHS EsterRelated Search:


  • (+)-Biotin-PEG8-NHS Ester
  • Biotin-PEG8-SPA
  • 4,7,10,13,16,19,22,25-Octaoxa-28-azatritriacontanoic acid, 33-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-29-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
  • 2,5-Dioxopyrrolidin-1-yl 29-oxo-33-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10,13,16,19,22,25-octaoxa-28-azatritriacontanoate
  • 2143968-03-8
  • SiChem
  • peg
  • Biotin