RET Kinase inhibitor 1
- Product Name
- RET Kinase inhibitor 1
- CAS No.
- 1627856-64-7
- Chemical Name
- RET Kinase inhibitor 1
- Synonyms
- CS-2597;GSK3179106;GSK-3179106;RET Kinase inhibitor 1;c-RET inhibitor GS3179106;Benzeneacetamide, 4-(4-ethoxy-1,6-dihydro-6-oxo-3-pyridinyl)-2-fluoro-N-[5-(2,2,2-trifluoro-1,1-dimethylethyl)-3-isoxazolyl]-;syndrome,post-inflammatory,visceral,stress-induced,irritable,RET,Inhibitor,bowel,hypersensitivity,orally,GSK 3179106,inhibit,IBS,GSK3179106,GSK-3179106
- CBNumber
- CB83356171
- Molecular Formula
- C22H21F4N3O4
- Formula Weight
- 467.41
- MOL File
- 1627856-64-7.mol
RET Kinase inhibitor 1 Property
- Boiling point:
- 670.1±55.0 °C(Predicted)
- Density
- 1.37±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO:81.0(Max Conc. mg/mL);173.29(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.53(Max Conc. mM)
Ethanol:15.5(Max Conc. mg/mL);33.16(Max Conc. mM) - form
- A crystalline solid
- pka
- 10.30±0.10(Predicted)
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 24023
- Product name
- RET Kinase Inhibitor 1
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 24023
- Product name
- RET Kinase Inhibitor 1
- Packaging
- 5mg
- Price
- $139
- Updated
- 2024/03/01
- Product number
- 24023
- Product name
- RET Kinase Inhibitor 1
- Packaging
- 10mg
- Price
- $243
- Updated
- 2024/03/01
- Product number
- 24023
- Product name
- RET Kinase Inhibitor 1
- Packaging
- 25mg
- Price
- $533
- Updated
- 2024/03/01
- Product number
- CS-7799
- Product name
- GSK3179106
- Purity
- 99.40%
- Packaging
- 1mg
- Price
- $50
- Updated
- 2021/12/16
RET Kinase inhibitor 1 Chemical Properties,Usage,Production
Description
GSK3179106 is an inhibitor of rearranged during transfection (RET) kinase (IC50 = 0.4 nM). It is selective for RET kinase over VEGF receptor 2 (VEGFR2/KDR; IC50 = 109 nM). GSK3179106 reduces the number of abdominal contractions induced by colorectal distension in acetic acid-sensitized rats when administered at a dose of 10 mg/kg twice per day.
RET Kinase inhibitor 1 Preparation Products And Raw materials
Raw materials
Preparation Products
RET Kinase inhibitor 1 Suppliers
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