2-HYDROXY-N,N-DIETHYLACETAMIDE Property

Boiling point:

238 °C (lit.)

Density 

1.009 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.457(lit.)

Flash point:

220 °F

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Sparingly), Methanol (Slightly)

form 

Oil

color 

Colourless

Safety

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

2-HYDROXY-N,N-DIETHYLACETAMIDE Chemical Properties,Usage,Production

Uses

N,N-Diethyl-2-hydroxyacetamide is a reactant used in the synthesis of phosphonate prodrugs to increase the oral bioavailability of an antiviral agent 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA).