ChemicalBook > CAS DataBase List > Isobutyramide
Isobutyramide
- Product Name
- Isobutyramide
- CAS No.
- 563-83-7
- Chemical Name
- Isobutyramide
- Synonyms
- IBA;Propanamide, 2-methyl-;2-methylpropanamide isobutyramide;2-Methyl-propanamide;VX 366;Butyl aMide;Isobuytramide;ISOBUTYRAMIDE;isobutyric amide;Isobutyramide>
- CBNumber
- CB8344674
- Molecular Formula
- C4H9NO
- Formula Weight
- 87.12
- MOL File
- 563-83-7.mol
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Isobutyramide Property
- Melting point:
- 127-131 °C (lit.)
- Boiling point:
- 216-220 °C (lit.)
- Density
- 1.013 g/mL at 25 °C (lit.)
- refractive index
- 1.4345 (estimate)
- Flash point:
- 216-220°C
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform (Sparingly), DMSO (Slightly)
- form
- Solid
- pka
- 16.60±0.50(Predicted)
- color
- White to Off-White
- Water Solubility
- Soluble in water.
- LogP
- 0.003 (est)
- CAS DataBase Reference
- 563-83-7(CAS DataBase Reference)
- NIST Chemistry Reference
- Propanamide, 2-methyl-(563-83-7)
- EPA Substance Registry System
- Propanamide, 2-methyl- (563-83-7)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 144436
- Product name
- Isobutyramide
- Purity
- 99%
- Packaging
- 25g
- Price
- $71.4
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 144436
- Product name
- Isobutyramide
- Purity
- 99%
- Packaging
- 100g
- Price
- $186
- Updated
- 2024/03/01
TCI Chemical
- Product number
- I0102
- Product name
- Isobutyramide
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $55
- Updated
- 2024/03/01
TCI Chemical
- Product number
- I0102
- Product name
- Isobutyramide
- Purity
- >98.0%(GC)
- Packaging
- 500g
- Price
- $635
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- B21641
- Product name
- Isobutyramide, 99%
- Packaging
- 25g
- Price
- $58.65
- Updated
- 2024/03/01
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Isobutyramide Chemical Properties,Usage,Production
Chemical Properties
white needle-like crystalline powder
Uses
Isobutyramide could be a useful compound for technical applications as a component in environmentally-friendly automobile welding anti-spatter liquid.
Uses
Isobutyramide plays an important role in chemical grafting of human serum albumin during the synthesis of sequentially assembled protein capsules. It is used in pharmaceutical manufacturing and in cellular differentiation. It finds application in the transcription of human gamma-globin gene and murine embryonic epsilon(y)-globin gene. Further, it is in the treatment of beta-thalassemia and sickle cell disease.
Definition
ChEBI: Isobutyramide is a carboximidic acid.
Application
Isobutyramide was used for chemical grafting of human serum albumin during the synthesis of sequentialy assembled protein capsules.
Isobutyramide plays an important role in chemical grafting of human serum albumin during the synthesis of sequentially assembled protein capsules. It is used in pharmaceutical manufacturing and in cellular differentiation. It finds application in the transcription of human gamma-globin gene and murine embryonic epsilon(y)-globin gene. Further, it is in the treatment of beta-thalassemia and sickle cell disease.
Synthesis Reference(s)
Journal of the American Chemical Society, 69, p. 2058, 1947 DOI: 10.1021/ja01200a070
Biochem/physiol Actions
Isobutyramide activates transcription of human gamma-globin gene and murine embryonic epsilon(y)-globin gene. It is useful in the treatment of β-thalassemia and sickle cell disease.
Purification Methods
Crystallise the amide from acetone, *benzene, CHCl3, EtOAc or water, then dry it under vacuum over P2O5 or 99% at H2SO4, or at 70o/3hours in a desiccator. Sublime it under vacuum. [Kent & McAlvain Org Synth Coll Vol III 491 1955, Beilstein 2 H 293, 2 I 129, 2 II 262, 2 III 654, 2 IV 852.]
Isobutyramide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Isobutyramide manufacturers
Hebei Zhuanglai Chemical Trading Co.,Ltd
- Product
- Isobutyramide 563-83-7
- Price
- US $180.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-06-03
Hebei Weibang Biotechnology Co., Ltd
- Product
- Isobutyramide 563-83-7
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-13
Hebei Mojin Biotechnology Co., Ltd
- Product
- Isobutyramide 563-83-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50000KG/month
- Release date
- 2023-08-24
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