ChemicalBook > CAS DataBase List > 13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2

13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2

Product Name
13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2
CAS No.
363-23-5
Chemical Name
13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2
Synonyms
PGEM;13,14-Dihydro-15-keto-PGE2;CUJMXIQZWPZMNQ-XYYGWQPLSA-N;15-keto-13,14-dihydroprostaglandine2;13,14-dihydro-15-oxo-prostaglandin E2;13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2;13,14-Dihydro-15-ketoprostaglandinE2 solution;9,15-DIOXO-11ALPHA-HYDROXY-PROST-5Z-EN-1-OIC ACID;(5Z)-11α-Hydroxy-9,15-dioxoprosta-5-ene-1-oic acid;(5Z,11α)-11-Hydroxy-9,15-dioxoprost-5-en-1-oic acid
CBNumber
CB8349316
Molecular Formula
C20H32O5
Formula Weight
352.47
MOL File
363-23-5.mol
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13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 Property

Boiling point:
538.1±45.0 °C(Predicted)
Density 
1.086±0.06 g/cm3(Predicted)
storage temp. 
−20°C
pka
4.75±0.10(Predicted)
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Safety

Hazard Codes 
F,Xn,Xi
Risk Statements 
11-20/21/22-36/37/38-67-66-36
Safety Statements 
16-26-36
RIDADR 
UN 1231 3/PG 2
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

H351Suspected of causing cancer

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
14650
Product name
13,14-dihydro-15-keto Prostaglandin E2
Purity
≥95%
Packaging
1mg
Price
$77
Updated
2024/03/01
Cayman Chemical
Product number
14650
Product name
13,14-dihydro-15-keto Prostaglandin E2
Purity
≥95%
Packaging
5mg
Price
$340
Updated
2024/03/01
Cayman Chemical
Product number
14650
Product name
13,14-dihydro-15-keto Prostaglandin E2
Purity
≥95%
Packaging
10mg
Price
$602
Updated
2024/03/01
Cayman Chemical
Product number
10007214
Product name
13,14-dihydro-15-keto Prostaglandin E2 MaxSpec? Standard
Purity
>95%
Packaging
100μg
Price
$118
Updated
2023/06/20
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13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 Chemical Properties,Usage,Production

Description

13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) is a metabolite of PGE2 and the primary PGE2 metabolite in plasma. It is formed from PGE2 via a 15-keto PGE2 intermediate by 15-oxo-PG Δ13 reductase. Unlike PGE2, 13,14-dihydro-15-keto PGE2 does not bind effectively to the PGE2 receptors EP2 and EP4 expressed in CHO cells (Kis = 12 and 57 μM, respectively) or induce adenylate cyclase activity in the same cells (EC50s = >18 and >38 μM, respectively). Levels of 13,14-dihydro-15-keto PGE2 are increased in the plasma of women in the third trimester of pregnancy and in women during and immediately after labor and delivery. Levels of 13,14-dihydro-15-keto PGE2 levels are decreased in tumor tissue compared to adjacent non-cancerous tissue isolated from patients with non-small cell lung cancer (NSCLC).

Uses

13,14-Dihydro-15-ketoPGE2 is a primary metabolite of PGE2 in plasma.

Definition

ChEBI: The 13,14-dihydro derivative of 15-oxo-prostaglandin E2.

13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 Preparation Products And Raw materials

Raw materials

Preparation Products

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13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2 Suppliers

Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9709
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6870
Advantage
58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd
Tel
0571-85361029
Fax
0571-85361029
Email
synstar518@163.com
Country
China
ProdList
1991
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11289
Advantage
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Hubei Kele Fine Chemical Co., Ltd
Tel
027-59101668 19945030958
Fax
027-59101668
Email
2881924765@qq.com
Country
China
ProdList
7974
Advantage
58
amyjetsci
Tel
027-59626688 18771149750
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sales@amyjet.com
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China
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Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
+86-18521732826
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market@aladdin-e.com
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China
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48467
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Wuhan Topule Biopharmaceutical Co., Ltd
Tel
+8618327326525
Email
masar@topule.com
Country
China
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8474
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363-23-5, 13,14-DIHYDRO-15-KETO PROSTAGLANDIN E2Related Search:


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